Just a quick post here to share an amazing, published fact with those who may still have doubts about the virtually unlimited disease states deliverable through vaccinations and other injectable, pharmaceutical drugs… you know, the ones on TV commercials that warn of side effects like death, cancers, heart attack, high cholesterol, prion-type disease, etc? But today, we are simply going to look at a rather popular vaccine insert for a vaccine targeted for infants and children under 7 years old only. That vaccine is called Tripedia®, Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed (DTaP), (Sanofi Pasteur Inc.). We find the following statement on page 3 of the actual insert, located at the bottom of the page, last paragraph:
TRIPEDIA: Package Insert and Label Information (Page 3 of 4)
“…Adverse events reported during post-approval use of Tripedia vaccine include idiopathic thrombocytopenic purpura, SIDS, anaphylactic reaction, cellulitis, autism, convulsion/grand mal convulsion, encephalopathy, hypotonia, neuropathy, somnolence and apnea. Events were included in this list because of the seriousness or frequency of reporting. Because these events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequencies or to establish a causal relationship to components of Tripedia vaccine.”
I need not say any more here, for the proof is definitely in the pudding. This cannot be denied in any sane capacity. And it has sparked me even further into mentally preparing to make another vaccine documentary.
It occurs to me that any doctor that has recommended or delivered this particular vaccine while also assuring parents of the safety and non-relation to autism when it is printed right in the insert should be sued immediately for malpractice and fraud to have his license taken away, for whether it was pure ignorance or a manufactured lie, neither of these are good excuses. An ignorant, compartmentalized doctor is the most dangerous, licensed killer on earth. In fact, according to statistics tallied by the Journal of the American Medical Association (JAMA) and many other journal and governmental sources in consideration of death by iatrogenic (doctor/medicine-related) causes, doctors are the third leading cause of death in the United States! Reported at many sources, this is from US News.com:
Medical Errors Are Third Leading Cause of Death in the U.S.
“10 percent of U.S. deaths are due to preventable medical mistakes.”
“…MEDICAL ERRORS ARE THE third leading cause of death in the U.S., after heart disease and cancer, causing at least 250,000 deaths every year, according to an analysis out Tuesday indicating that patient safety efforts fall far short…”
“…Throughout the world, medical error leading to patient death is an under-recognized epidemic,” Makary and his co-author, Dr. Michael Daniel, also of Johns Hopkins, write in Tuesday’s British Medical Journal. They define medical errors as lapses in judgment, skill or coordination of care; mistaken diagnoses; system failures that lead to patient deaths or the failure to rescue dying patients; and preventable complications of care.
Their report comes nearly two decades after “To Err is Human,” a report by the Institute of Medicine, asserted that medical mistakes are rampant in health care. The IOM, a quasi-public think tank made up of leading scientists, drew on existing data to estimate that 44,000 to 98,000 people die in U.S. hospitals each year. Even then, some researchers claimed the estimates were low and based on outdated information.
The new estimate is drawn from more-recent studies indicating the number may be much higher. For instance, a report published in the journal Health Affairs in 2011 calculated that just over 1 percent of hospital patients die each year because of medical errors. When applied to the more than 35 million people hospitalized each year, Makary and Daniel say, this would “translate into 400,201 deaths per year, more than four times the original IOM report estimate.”
The Hopkins team used evidence from four studies that analyzed medical death rate data from 2000 to 2008, including one by the U.S. Department of Health and Human Services’ Office of the Inspector General and the Agency for Healthcare Research and Quality. Using these data, they were able to calculate a mean death rate for medical errors in U.S. hospitals. Applying this rate to the 35 million admissions in 2013, they calculated that 251,454 deaths resulted from medical mistakes…”
As a final note, let us not confuse this with the pointless debate on whether vaccines work or not. That is not the issue in any way here. The only issue is that the extra ingredients in vaccines and other injectable drugs, specifically metals and animal or human proteins and cancer viruses too small to filter out of the final product, are what is causing these seemingly unrelated diseases. And these “slow” diseases can happen days, months, years, or decades after one receives a vaccine. Please look beyond the mainstream debate and into the completely arbitrary and usually unnecessary ingredients list. These extraneous ingredients are listed above (in the insert) as “COMPONENTS” of the vaccine.
Please share this with any and all you can. This cannot go unspoken.
The time has come that, at least for now and the near future, I am retiring this blog. It will not be actively contributed to anymore by myself. Now, please allow me to explain why.
I feel that I have reached the end of this particular journey. And though my future path remains unclear as of this moment, I have faith that this past journey and the heartbreak it has caused me was not only necessary, but that it will also lead myself and perhaps others to a better place. I am in these strange days at a conscious fork in the road, under what some may call technologically (artfully) the final days of whatever life as we have pretended to know and accept it is.
The following is literally a walkthrough of my time on this earth as an activist turned writer, filmmaker, and radio guest and host. Some of the links provided below have likely not been seen by most of my readers, a personal history lost in the shit-pile of Youtube feces and tabloid nonsense. This is my history (his story) as publicly recored, for better and for worse, and as it remains in that digital ether like the story of a child growing up and out of his own societal, political, and religious delusions.
My future, my path, depends on you. I will either be able to print my life’s work, my new books, or I will not. I will either use those reference books as my tool or I will not. And as for myself, I will either fade away into the obscurity we were birthed into or I will overcome it. Honestly, this option to fade away (or burning out) sounds like a much easier path right about now. And so I am posting here what may very well be my last post on this blog. I am posting here my life story as an activist, writer, filmmaker, radio show host, and guerrilla journalist, all of which I have funded out of my own already empty pockets.
And so Iam asking you the reader, watcher, and listener just what my work has been worth to you?
There are currently 1861 subscribers to this blog. It receives an average of between 500-700 readers per day that click on one of 241 published posts representing uncountable hours of research. A total of 1,422,654 views have occurred over this blogs 7 year history, all of them without charge and certainly without profit and gain for the benefit of their author (figures as of Aug-01-2016). And so I am asking, for the second and last time, that my readers support this tome of research and work by donating to my cause. All donations will be applied solely towards the private printing of my books. If every subscriber donated just $10 today I would reach my goal instantly.
But I have nothing left to offer and certainly nothing to sell, except what I have already given away for free and what I will continue to offer freely in the future. The book is already posted for free download here: StrawmanStory.info, with Volume II soon to follow and be added to the first.
Please donate (click) here:
Or my P. O. Box is at:
Clint Richardson 1192 East Draper Parkway #124 Draper, Ut 84020
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If you would like a paperback copy of the book, please follow the instructions at the StrawmanStory.info home page, as this would be a purely private, non-commercial exchange.
Here, let me attempt to answer the question as to why you should make a donation.
I can only walk you through my story here, and can only offer my charitable life’s work and research below as the answer to that question. And so below is my personal walkthrough of just that.
I have poured my heart and soul into ten years of dedicated, full-time research, media, and activism, as is evidenced by this extensive blog. I have given the fruit of my labors freely without exception or expectation. I have suffered ridicule and fallacious personal attacks on my character by cowardly persons unknown, unseen, and unmet, and by those who hide behind false names and flattering avatars and titles for reasons I cannot fathom; a paid and usefully unpaid idiocy. I lost one email account and am apparently losing current emails into the nothingness of the cloud. I have had strikingly unreasonable rebukes, a strange absence of searchable content on search engines like Google, and just all around opposition (controlled and otherwise) for telling the untainted Truth that very few want or are capable of hearing. Though few seem to be seeking healthy debate or discussion, many are willing to throw stones and cause stumbling blocks from afar. I suppose this has become the American way, wearing our ignorance like a badge of courage. Hell, no government (mind control) is needed when we are each others own stumbling blocks and worst enemies.
Much of what I had uncovered years ago is now being recognized, propagandized, and institutionalized through an obfuscating normalization process. For instead of being outrightly hushed, it is being brought into public light slowly, as entertainment, so as to protect the pharmaceutical and medical industries that are ultimately responsible for spreading all modern disease through various forms of inoculation, including vaccination.
For instance:
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“Scientists might finally understand how prions spread infectious brain disease“
“After decades of research, scientists think they finally know what turns prions – healthy proteins inside our brains – into the infectious,virus-like pathogens that cause ‘mad cow’ disease, and have also been linked to Alzheimer’s and Parkinson’s…“
In Truth, this information has been known for decades, intentionally buried by drug companies under actuarial profit projections and insurance matrixes without responsible or even cautious recall. The careless results of such insured and government-approved and licensed irresponsibility (malpractice insurance) certainly could have been avoided if it were not for the religious worship of vaccination and other medical nightmares, which purposefully deliver cross-species infection and the RNA-based DNA reprogramming that leads to cancers and so many other diseases through such unnatural inoculations. Even this article is chalk full of misleading statements, never putting the blame upon the pharmaceutical companies that have hand delivered most modern diseases directly into our veins through the monetarily induced and brainwashed, licensed nurses and doctors that prescribe them, posing as if wasps stinging their prey to deliver their own burden of poisons and parasites.
Pulitzer Prize winner Richard Rhodes warned us in the 1980’s with his book “Deadly Feasts” about this modern, government and medically-induced plague, along with Patrick Jordan and myself (2011-12) intimately exposing it in this new century with 1,000’s of hours of primary research and radio shows on the subject. The amount of suffering that could have been and still can be averted is not qualifiable in blogosphere soundbites. This open secret is kept merely to protect the deliverers of these infectious prions and their profitable “big pharma” corporations, even as most modern “dementia” type dis-ease has in fact been shown to be some form of prion dis-ease as an otherwise impossible cross-species infection. They actually call this “prion misfolding,” which is just another word for “evolution” (the unfolding of man and beast). But who would listen to a lowly old blogger and an obscure couple of unpublished authors that voluntarily sacrificed their entire livelihoods to literally save the population from its own ignorant trust in flatteringly titled, legal “doctors” and the regulatory agencies of government that “educate” and license them in their practice of spreading disease through professional prescription?
Evolution, or as polio vaccine inventor Jonas Salk called it, The Unfolding Of Man, is not merely some random act of Nature. It is a purposeful infection (by a penetrating needle sting) that causes healthy cells to be mis-folded into whatever RNA structure is infecting and reprogramming its functionality and form. This evolution is often called cancerous growth. For instance, the scrapie prion of sheep causes mad-cow disease in cattle, as the genetic programming of the sheep prion attempts to reprogram the specifically and proprietarily naturally programmed cow prion, evolving it and thus causing the symptoms of doctor and drug-induced evolution. This process is called prion misfolding, and foreign prions (all prions of all other species) are called “infectious” for this reason, as they attach to healthy, proprietary (host) prions and literally evolve (unfold) them into copies of their foreignly programed selves.
I do not use this word evolution lightly. This is not a sophomoric religious or scientific debate. This is the real deal. The evil elements in this world have found a way to literally evolve us through these deadly and pretended-to-be incurable, infectious prions. This is the weaponization of the very design of life itself, the purposeful altering of prion proteins that are designed to, by their own source of nature and in a foundational way, protect us from so many special diseases, including most forms of cancer. But these diseases can only happen in man and beast when purposeful cross-species contamination takes place, and only man can contemplate and manufacture such evil in the name of unnatural, unspiritual “science” and “medicine.”
EVOLUTION –noun – [Latin evolutio.] The act of unfolding or unrolling. 1.A series of things unrolled or unfolded; as the evolution of ages… 4. In military tactics, the doubling of ranks or files, wheeling, countermarching or other motion by which the disposition of troops is changed, in order to attack or defend with more advantage, or to occupy a different post.
EVOLVE –verb transitive – evolv’. [Latin evolvo; e and volvo, to roll; Eng. to wallow.] 1.To unfold; to open and expand. The animal soul sooner evolves itself to its full orb and extent than the human soul. 2. To throw out; to emit. – verb intransitive – To open itself; to disclose itself.
–Webster’s 1828 Dictionary of the English Language
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Jonas Salk, inventor of the injectable, inactivated live-virus polio vaccine that spread so much infectious disease (including polio) around the world due to the un-filterable protein (infectious prion) and DNA strands of Simean Monkey Virus #40 (SV-40) and other infectious cancer viruses mixed with other biological-unfolding agents, later released a selection of very telling books based on his research into this purposeful evolution of life, some of those titles being “Man Unfolding” and “Infectious Molecules and Human Disease.“
The actual history of his ilk’s work is still underreported and ignored as fools line up in droves to accept their devil-in-a-white-coat’s inoculative tribute from nurses that know not the first thing about these pharmaceutical weapons they are paid to deliver under licensure by those syndicalist, organized crime dealers of purchased degrees and diplomas.
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“Official data shows that large scale vaccination has failed to obtain any significant improvement of the diseases against which they were supposed to provide protection.”
–Dr. Albert B. Sabin, inventer of oral or “sugar cube” polio vaccine
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“…nearly all polio outbreaks since 1961 were caused by the oral polio vaccine.”
–Jonas Salk, inventor of the first polio vaccine,
testimony before a Senate subcommittee
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“Many here voice a silent view that the Salk and Sabin Polio Vaccines, being made from monkey kidney tissue, has been directly responsible for the major increase in leukaemia in this country.”
–Dr. F. Klenner, MD
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“90% of polio cases were eliminated from statistics by health authorities’ redefinition of the disease when the vaccine was introduced, while in reality the Salk vaccine was continuing to cause paralytic polio in several countries at a time when there were no epidemics being caused by the wild virus.“
–Dr. Viera Scheibner, Ph.D.
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“Not only did the cases of polio increase substantially after mandatory vaccinations (a 50% increase from 1957 to 1958, and an 80% increase from 1958 to 1959), but the statistics were manipulated by the Public Health Service to give the opposite impression.”
–1962 U.S. Congressional hearings, excerpt of the testimony of Dr. Bernard Greenberg, Head of the Dept. of Biostatistics for the University of North Carolina School of Public Health
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“We now know that chronic fatigue syndrome (myalgic encephalomyelitis in England) is not a new disease, but simply an ‘aborted form’ of the more serious paralytic polio…“
That the sustained use of polio vaccines for over 40 years has resulted in:
“at least 72 viral strains that can cause polio-like diseases…”
Vaccinations caused:
“…the CHANGING of polio rather than the elimination of it.”
–Dr. William C. Douglas, M.D., Editor of the medical newsletter “Second Opinion”
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“[Conservatively] About 54 percent of children lamed as a result of poliomyelitis had received three doses of oral polio vaccine before the onset of paralysis.”
–Poliomyelitis trends in Pondicherry, South India, 1989-91, from the Journal of Epidemiology and Community Health [London], vol. 51, no. 4, August 1997, pages 443-48
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“Vaccines caused substantial increases in polio after years of steady declines, and they are the sole cause of new polio cases in the U.S. today.”
–Alan Phillips, independent investigator and writer on vaccine risks and alternatives, from a report published in the April 1996 edition of “Wildfire Magazine”
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I recently spoke of this medically induced evolutionary processing of the human race in an interview…
The vaccine for any dis-ease offers no positive healing factor, instead merely presenting an evolution or devolution of that dis-ease’s regiment of symptoms. As Patrick Jordan points out, to cure is to preserve, not to heal. We cure dead animals for later consumption by applying salt or other chemicals. We cure hay as well with salts, preventing its natural petrification but never allowing it to grow as if it were not already attacked and killed at its roots, left to a slow, decomposing death. But this is not healing, for the zombie dead that we are being turned into simply cannot be healed, only preserved (cured).
And though no vaccine manufacturer has ever made any claim or proven to “cure” any disease through vaccination, one must consider that zombies must also be cured so that their dying, petrifying bodies do not fall apart by the man-made diseases that caused their inconvenient disposition. We are certainly being cured in this villainous sense by these pharmaceutical corporations, for to alter the very DNA structure of man and beast, the symptoms of such man-made evolutionary changes must be managed. The body must be made to persevere through its forced alteration into that which is incompatible with Nature. It must be supplemented with poisons and chemical polymers and compounds that are otherwise unusable to the properly folded (un-evolved) man. We are as pieces of patented, copyrighted art being kept by museum curators, our altered and evolved genes continuously re-registered as government property, even as we mutate exponentially into our unwitting, transhumanist future.
For Charles Darwin, we find the term “descent” used in place of evolution in his first offering of “The Descent of Man” (1871), just one year before his “Origin of Species” attempted to fulfill the anti-theist’s wet dream.
It is ironic that this very tool of genetic and unique, non-nucleatoid protein manipulation that is the foreign (infectious) prion actually proves that evolution is quite naturally impossible in the way that Darwin theorized, and that only the adversarial (evil) and artful designs of the sciences of man may forcibly alter the very fundamental designs of Nature (God). The protective element of our natural, inheritable, healthy prion structure is the best and most sound evidence against Darwin’s origin of species argument. We simply cannot tolerate the cells of other species in our bodies, for their very RNA script and programming is diametrically opposed to our own. Hell, we can barley survive our own blood-types being crossed in normal reproduction without man’s interference though pharmacopeia to deaden our immune system that registers a forming baby of a foreign human blood-type as a foreign infection to be destroyed as a systematic dis-ease. Thus, to even suggest this foolish evolutionary theory as sound when considering this modern prion plague is outlandishly ridiculous, for infectious prions to humans are merely the healthy, normally occurring prions of other species. To each species lies its own origins. And to claim knowledge of those origins is only the false imaginations of idolatrous, want-to-be gods.
One of the most spiritual aspects and teachings of the Bible is simply that man can never know the origins of that which is his or any other source of True Existence. This humbling, self-evident knowledge is what drives insane men on such foolish errands in the flattering title of “science.” But the only Truth is that we will never know. We are not supposed to know. We are only supposed to live as we were intended to and by the very protective Design Nature allows. To question the integrity of that design and to seek improvement upon it is the greatest folly of man, who’s modern consciousness seeks only advancement and growth without reason or end. Our lot in life is to protect, not to alter our own Nature.
DESCENT – noun – 1. The act of descending; the act of passing from a higher to a lower place, by any form of motion, as by walking, riding, rolling, sliding, sinking or falling. 2.Inclination downward; obliquity; slope; declivity; as the descent of a hill, or a roof. 3.Progress downward; as the descent from higher to lower orders of beings. 4.Fall from a higher to a lower state or station. 5. A landing from ships; invasion of troops from the sea; as, to make a descent on Cuba. 6.A passing from an ancestor to an heir; transmission by succession or inheritance, as the descent of an estate or a title from the father to the son.Descent is lineal, when it proceeds directly from the father to the son, and from the son to the grandson; collateral, when it proceeds from a man to his brother, nephew or other collateral representative. 7.A proceeding from an original or progenitor. The Jews boast of their descent from Abraham. Hence, 8. Birth; extraction; lineage; as a noble descent. 9. A generation; a single degree in the scale of genealogy; distance from the common ancestor. No man is a thousand descents from Adam. 10. Offspring; issue; descendants. The care of our descent perplexes most. 11.A rank in the scale of subordination. 12.Lowest place. 13. In music, a passing from a note or sound to one more grave or less acute.
–Webster’s 1828 Dictionary of the English Language
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At some point, man becomes unman. At some point, man becomes a proprietary creation of man. At some point, man is no longer a creation of God (the Source of Nature) but an invention of a corporation (artificial person) under the authority of the government that corporation (person) is registered in. That time is upon us. We must choose our master, man’s designer A.I. machine or God’s Nature.
But this “unfolding” is not merely biological, for the mind and moral compass of man’s development must also be evolved to meet the changing nature of these so-called “sciences,” of transhumanism and other unnatural developments as the evolution or unfolding of man continues as an unabated “science.” One does not teach men born to be slaves the language of their masters, lest the carefully divided classes become equals and sit at the same tables. Of course, “education” is the best method towards unfolding (evolving) the impressionable young minds of all men so that they may come to culturally accept such scientific madness as a normality, and even as if it were the natural evolution of man. And are we not seeing just that, as new generations are being systematically confounded and reprogrammed to accept this artificially induced evolutionary process of augmented reality? For the the concept of a New World Order is merely the combining of all that stands in opposition into togetherness, a fusion of the real and unreal, life and non-life, spirit and flesh.
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The Unfolding of Man. Research Note. Educational Policy Research Center – 67-47-
Author: Naranjo, Claudio
“Material gathered from education, religion, medicine and related fields comprises this practical approach to dealing with human development. The unity underlying the multiplicity of ways of growth (150 educational methods or systems) is a recurrent theme. This unity transcends the seemingly diverse intentions of education, psychiatry, and religion. The author contends that close scrutiny may uncover enough of a meeting ground to warrant the ambition of a unified science and ART OF HUMAN CHANGE. Indeed, a consistent view of man’s development will fuse the three currently separated disciplines. The author suggests a phenomenological approach to practical ways of personal growth which provides an experiential meeting ground for diverse techniques, exercises and procedures that would contribute to the UNFOLDING OF MAN. His approach is intended to elucidate two things: (1) THE UNITIY OF SECULAR AND RELIGIOUS VIEWS CONCERNING THE PROCESS OF THE UNFOLDING OF MAN;and (2) the unity of various methods of achieving human growth from the standpoint of experiences these methods elicit, rather than from their external descriptions. (TL)”
Notice here folks: that’s a government website; an “educational” website. That’s the goal of the modern Common Core principle. Government controlled education… no wonder people are patriotic towards their own military occupier and destroyer, for it controls their intake of knowledge and thus hides its own intent. The pawns actually believe they are kings.
This is a multi-front attack. The A.I. is on. All systems go.
Of course the official “education” system will dispense with True religious and moral teaching towards the improved and evolved teaching of man’s scientific control of perceived “chaos” through this artificial, neo-humanistic order birthed from it. Man’s very soul must be misfolded with worthless fruit, the unnatural and seedless (groundless) information from that tree of the good and evil conceptualizations and inventions (fictions) of man.
One last note on this subject:
As I am not credentialed or respected by this official, consensus-based, syndicalist organized criminal element, and proudly so, I will put my thesis here. It is one that can change the world, and thus probably won’t go much further than this page. It is simply that prions prove Darwin’s theory of “natural” evolution to be completely false. In fact, it is this forced, unnatural evolution (unfolding) of man through prion misfolding that shows some form of “design,” be it “intelligent” or otherwise. This is not the point. The point is that cross-species transmission of these smallest of proteinaceous agents is infectious, causing great dis-ease to the host body. In other words, the symptoms are a sign that under no circumstances can two species be compatible, let along derived from each other. If man came from ape, then man’s body should be receptive to its source protein structure and biological programming. But it is not. In all cases of xenotransplantation (animal to human body part replacement) the immune system treats that special part as a foreign infection, and so the immune system must be nullified through pharmacopeia (witchcraft, potions, and poisoning) for the body to accept any foreign transplant. They simply are not compatible in a “natural” way. Thus “natural” evolution, at least as the “origin of species,” is bunk. Cancer is a symptom of evolution, for cancer is a direct response of the body to foreign (non-human) DNA programing, sometimes referred to as cancer “viruses.”
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Viruses that can lead to cancer
Viruses are very small organisms; most can’t even be seen with an ordinary microscope. They are made up of a small number of genes in the form of DNA or RNA surrounded by A PROTEIN COATING.A virus must enter a living cell and “hijack” the cell’s machinery in order to reproduce and make more viruses. Some viruses do this by inserting their own DNA (or RNA) into that of the host cell. When the DNA or RNA affects the host cell’s genes, it can push the cell toward becoming cancer.
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You’ll notice that most “cancer viruses” are from monkeys and other animals, which must be manually (purposefully) injected into the human body to cause infection, or transplanted in some other way. Other viruses that cause cancer, such as HPV, are also foreign agents, in this case a “wart” passed from human to human. The supposed HIV virus is another example, extremely similar to feline immunodeficiency virus (i.e. the supposed cause of feline AIDS), which can only cause disease when injected into the body, either through transmission or other cross-species contact. Whether it is actually a sexually transmitted disease is not clear or proven, and I have never known an unvaccinated (or non-intervenious drug-user) or other “blood product” user via inoculation of foreign or human blood pharmaceuticals to have the symptoms of AIDS or cancer.
This trend in cancer rates was documented in its early stages just after the turn of the 20th century:
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“Cancer was practically unknown until compulsory vaccination with COWPOX vaccine began to be introduced. I have had to deal with two hundred cases of cancer, and I never saw a case of cancer in an unvaccinated person.“
–Dr. W.B. Clarke, a prominent physician in Indiana, from Eustace Mullins ‘Murder by Injection,’ pg 132, quoting The National Council for Medical Research, Virginia
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And so I reiterate Dr. Clarke’s respected opinion here when I say that evolution was practically unknown until vaccination became commonplace, and that most modern diseases are in fact the symptoms of cross-species infection through vaccination. Whether vaccination “works” or does not is irrelevant at this point. For it is how they are grown and the delivery of unfiltered proteins and DNA that is the subject at hand. This has nothing to do with the theory of “vaccination” and everything to do with cross-species contamination. There is no left or right, right or wrong. There is only the fact that most of us have been infected with the DNA and prion proteins of many, many different species that vaccine cell substrates are grown on! To this fact, every vaccine insert warns us! This is wholly against every aspect of the Natural Law, the scriptural Law, and the law of reason. To this fact there is no debate.
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“Eaten blood is digested into its components so it ceases to be blood, and the body re-uses the components for different things. Transfused blood is not digested but functions as blood with all its vital properties for life.”
—Jonathan Sarfati, Ph.D., excerpt from an article entitled: “New England Journal of Medicine promotes anti-theism”
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“For the life of the flesh is in the blood…”
—Leviticus 17: 11, 14, KJB
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“VARIVAX [Varicella Virus Vaccine Live (Oka/Merck)]
VARIVAX… is a preperation of the Oka/Merck strain of live, attenuated varicella virus. The virus was initially obtained from a child with natural baricella, then introduced into human embryonic lung cell cultures, adapted to and propagated in embryonic guinea pig cell cultures and finally propagated in human diploid cell cultures (WI-38). Further passage of the virus for varicella vaccine was performed at Merck Research Laboratories (MRL) in human diploid cell cultures (MRC-5)…
Each 0.5 mL dose of vaccine contains the following… residual components of MRC-5 cells including DNA and PROTEIN.“
—Except taken directly from VARIVAX insert from actual vaccine package
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The FDA is certainly aware of all this, and has been for a long time. It is a protective agent not for us, but for the corporations that government invests in and controls. The reader should ask themselves why vaccines are allowed to be used on the public and on pets when this type of information is readily available. But then, the reader would have to lose such fallacies as patriotism and love of country (love of artificial persons). We’s have to face reality, which is just too painful…
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“Potential Risks of DNA in Vaccines
“Residual DNA in vaccines derived from tumorigenic cells, including those transformed by Ad5, can pose potential risks to the vaccine recipient in two respects: oncogenicity and infectivity. Each of these biological properties must be considered and evaluated for each cell substrate.
“The oncogenic risk of cell substrate DNA has been considered to be due to several mechanisms. First, the residual DNA could have dominant activated oncogenes that could exert their effect following expression in recipient cells. In the case of Ad5-transformed cells, the dominant oncogenes would include the E1A and E1B genes. Second,the incoming DNA could integrate into the host genome in certain genes, such as the p53 gene or the retinoblastoma susceptibility (RB) gene, termed tumor suppressor genes, which are involved in cell cycle control among other cellular processes.Loss of function of tumor suppressor genes has been associated with certain human tumors. Third, integration of residual cell-substrate DNA could result in the activation of cellular regulatory genes by promoter/enhancer insertion, and this could result in the development of a neoplastic phenotype; this mechanism for tumor development was initially described in chickens for leukemia formation by avian leukosis viruses. Another result of integration that has been described is an increased methylation of adjacent DNA sequences as well as sequences on other chromosomes, although the consequences of such changes in methylation patterns to a cell are unknown.
“The second biological activity of DNA that should be considered is its potential infectivity.If a genome of a DNA virus or the provirus of a retrovirus is present in the cell substrate used for vaccine manufacture, then the residual DNA has the potential, upon inoculation into the vaccine recipient, to produce infectious virus from this DNA and thus establish a productive infection.
“The assessment of the risk of DNA — both the oncogenic risk and the infectious risk — needs to be considered both in terms of (1) the amount of residual DNA inoculated; and (2) the concentration of oncogene or infectious genome present in this DNA…
“In considering potential risks associated with the use of these so-called Designer Cell Substrates – i.e., neoplastic cells derived from normal human cells transformed by defined viral or cellular oncogenes or by immortalizing cellular genes (e.g., telomerase) – OVRR/CBER is considering the approach outlined below within the framework of a “defined-risks” assessment… “A defined-risks approach to the regulatory assessment of the use of neoplastic cells as substrates for viral vaccine manufacture”, In EVOLVING Scientific and Regulatory Perspectives on Cell Substrates for Vaccine Development… The use of immortalized,neoplastic human cells as substrates to develop recombinant viral vectors as vaccines also raises theoretical concerns with regard to possible contamination with TSE/BSE(Human/transmissible form of Mad Cow Disease) agents.”
—FDA article from FDA website entitled “‘Designer’ Cells as Substrates for the Manufacture of Viral Vaccines”
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We are being unwittingly evolved!
We marvel and cringe at the effects of “mad cow disease,” which is merely a prion disease caused by vaccinating (stinging) a healthy cow with infectiously programed sheep prions, and yet we treat our own madnesses called as the many names of “dementia” as somehow expected, age-related, and naturally occurring. We suffer this evil like good little patients, paying for “cures” that do not work from the very industry that intentionally knowingly infected us in the first place.
But then, the word patient is one of my favorite words, for we have no clue that we are patients of government from our birth. In fact, a citizenship is nothing more and nothing less than a patient of a government institution.
PATIENT –adjective – pa’shent. [Latin patient.] 1.Having the quality of enduring evils without murmuring or fretfulness;sustaining afflictions of body or mind with fortitude, calmness or christian submission to the divine will; as a patient person, or a person of patient temper. It is followed by of, before the evil endured; as patient of labor or pain; patient of heat or cold. 2.Not easily provoked;calm under the sufferance of injuries or offenses; not revengeful. Be patient towards all men. 1 Thessalonians 5:14. 3.Persevering; constant in pursuit or exertion; calmly diligent. Whatever I have done is due to patient thought. 4. Not hasty; not over eager or impetuous; waiting or expecting with calmness or without discontent. Not patient to expect the turns of fate. – noun – A person or thing that received impressions from external agents; he or that which is passively affected. Malice is a passion so impetuous and precipitate, that it often involves the agent and the patient.1.A person diseased or suffering bodily indisposition. It is used in relation to the physician; as, the physician visits his patient morning and evening. 2. It is sometimes used absolutely for a sick person. It is wonderful to observe how inapprehensive these patients are of their disease. –verb intransitive –To compose one’s self. [Not used.]
–=–
What the hell are you all waiting for so patiently???
Now we must remember, only what is a unique or novel creation of man can be patented as property of man’s person (a franchised legal status of government). And the only cure for the disease of man’s law is to be only the property of God’ Nature (Creation). This isn’t religion, it’s common sense. It the Highest LAW, the Law of Nature! And it is completely tainted by the false doctrines of the corporate church, which is merely an authorized, non-profit agent and artificial person of the state, the very state that wishes to become your involuntary god (creator) and master. When man is no longer man, when his genes and genome are newly created, patented property of government and its syndicalist corporate structure, then we will be born slaves. We will carry our person (status) in our very unnatural, trans-human design, the mark of proprietary beasts. For we will have allowed ourselves to deny our own Nature, our own place within God, and instead to become a creation of man.
—=—
“The products of man’s imagination and undisciplined appetite may have a boomerang effect which in due time may well overpower him.”
—Jonas Salk, from: ‘Man Unfolding’
—=—
It is not difficult to understand at all. It’s real simple… Because we are not “religiously” following the Law of Nature, which is laid out succinctly in the Bible, and because we have thus lost respect for the very Laws (Design) of Nature Itself as we try and alter and improve upon them through unnatural evolution, we are dooming ourselves to a literal hell on earth. We are allowing ourselves to be controlled utterly by devils (attorneys).
DEVILING –noun – A young devil. (Webster’s 1828 Dictionary of the English Language)
DEVILLING – A term used in London of a barrister recently admitted to the bar, who assists a junior barrister in his professional work, without compensation and without appearing in any way in the matter.(Black’s Law 4th Edition)
DEVIL’S HORNS – When managers focus on an undesirable trait.They do not see future and current success potential. (Black’s Law 4th Edition)
DEVIL –noun – Devl. [Latin, to calumniate.] 1. In the Christian theology, an evil spirit or being; a fallen angel, expelled from heaven for rebellion against God; the chief of the apostate angels; the implacable enemy and tempter of the human race. In the New Testament, the word is frequently and erroneously used for demon. 2.A very wicked person, and in ludicrous language, an great evil. In profane language, it is an expletive expressing wonder, vexation, etc. 3.An idol,or false god.Leviticus 17:7. 2 Chronicles 11:15. (Webster’s 1828 Dictionary of the English Language)
DEMON – …Evil spirit or genius, which influences the conduct or directs the fortunes of mankind. (Webster’s 1828 Dictionary of the English Language)
DEMONIAC, DEMONIACAL or DEMONIAN – adjective – 1. Pertaining to demons or evil spirits. 2. Influenced by demons; produced by demons or evil spirits. (Webster’s 1828 Dictionary of the English Language)
DEMONIAC – Phrensy. – noun – A human being possessed by a demon; one whose volition and other mental faculties are overpowered, restrained, or disturbed, in their regular operation, by an evil spirit, or by a created spiritual being of superior power. (Webster’s 1828 Dictionary of the English Language)
CALUMNIATE – verb transitive – [See Calumny] To accuse or charge one falsely, and knowingly, with some crime, offense, or something, disreputable; to slander. – verb intransitive – To charge falsely and knowingly with a crime or offense; to propagate evil reports with a design to injure the reputation of another.(Webster’s 1828 Dictionary of the English Language)
CALUMNY –noun – Slander; false accusation of a crime or offense,knowingly or maliciously made or reported, to the injury of another; false representation of facts reproachful to another, made by design,and with knowledge of its falsehood; sometimes followed by on. Neglected calumny soon expires. (Webster’s 1828 Dictionary of the English Language)
–=–
Which demons possess you?
Would you even know as an evolved, unfolded pseudo-man?
What false gods do you allow to bedevil and calumniate you?
Just who or what are the devil’s advocates?
Trust me when I say that truth is way stranger than any church fiction…
For what you may not have comprehended quite yet is that we are speaking here of biological slander, a rewriting of our Source program, as the propagation of evil designs upon our very genomic structure. We are being bewitched and bedeviled at the cellular level, calumniated to an end that will cause us to be abhorrent to our Natural Source, and instead to one made by the design of these evil geniuses (human devils). We are being made criminals from God and Nature, chimeras that must be bound and chained for our offensive natures. Words will no longer be needed in this charge, for our crimes will be spelled out in our DNA sequence chains.
You see the great mystery is that all the monsters in the Bible, as well as all the saints, are just various forms of man. Man is the only species that acts against its own Nature and best interests. And so even as you cry foul and weep at the loss of this world you still refuse to pick up the one book that would save your very life and soul. For the designs of these devils in suits and ties and white lab coats is to make you into mere animals, which translates to soulless beasts, a purposefully designed lack of anima. The Bible is an instruction manual on how to avoid these devils, especially the ones that lurk in the church and state.
–=–
“Devilling, as the period of pupillage or training to become an advocate is generally known, lasts between eight and nine months, and comprises a mix of skills training courses and time spent working with a devilmaster. The compulsory skills training courses, which are described in more detail in the following pages, are spread across the devilling period and last for about nine weeks in total. For the balance of the period of devilling,devils work closely with their devilmasters.
“All devils have a principal devilmaster who is a practicing member of the junior barof at least seven years standing, and working primarily in civil practice.Devils will also spend part of the time with another devilmaster practicing in the criminal courts, and many devils spend a short period of time with a third devilmaster working in a different aspect of civil work from his or her principal devilmaster…
“The Faculty of Advocates is a body of independent lawyers who have been admitted to practice as Advocates before the Courts of Scotland. Faculty records date as far back as 1532when the College of Justice was established by an Act of the Scottish Parliament,though its origins are believed to predate that event.”
—Copied from from official UK website (advocates.org.uk), explaining the act of ‘Deviling’, and finally excerpted from its main “about” page. It is important to note that though this information on the “deviling” page was specifically removed in late 2015, but that its origin remains. This excerpt is taken from a 111 page publication entitled “The Devil’s Handbook,” 12th Edition, 2014/15, published by the Faculty of Advocates, Advocates Library, Parliament House, Edinburgh EH1 1RF
–=–
This is no joke! This is a government publication and is excerpted from a government website. This is the true nature of the umbrella of the International Bar Association (IBA) and its many national members.
But let us not go too far astray. For I have uncovered so much more of this artful design, and have removed the vail and barrier of popular debate from the equation. Debate is the great mountain of obfuscation, which, by its official rules, requires one to protect lies and stand in defense of what one does not believe in. This is professional debate, a tool used to train priests, politicians, and attorneys, or what I call the modern Pharisees.
I knew the debate on what are popularly named as “chemtrails” was over and pointless, for instance, when I found that the most “prestigious” universities around the world were teaching “Geo-Engineering” of the land, air, and seas and offering professional degrees and diplomatic papers (diplomas) therein. No geo-engineering or chemtrail skeptic can overlook the fact that this monster of organized crime against nature, which by illusion labeled (named/noun) as the sponsored and regulated “education” system of government, is offering degrees and therefore a requirement for legal licensure in geo-engineering the entire planet! The debate, I found, was merely a smokescreen as obvious to the senses as the chemtrails themselves, designed to make the common man believe not even his own eyes.
And so we find that all we have been exposing for so many years, decades in fact, is now the subject of dinner conversation and climate change discussions, as we – the boys who supposedly cried wolf – are now conveniently forgotten instead of just outright ignored.
Here is a perfect example of the respect garnered to these false, flattering titles of mega-corporations, as that which is allotted to this syndicalist “education” monopoly of the state. Under the top 10 rankings of schools and universities is listed each one by rank of prestige, with an imaginary, non-referential “score” placed next to each institution as its numerical ranking according to that pretended, apparitional quality of prestige. Ironically, most folks would actually choose which schools they wish to attend by these so-called rankings in “prestige” having no idea the actual root meaning of that word.
Here’s the top 10 schools ranked by their so-called prestige:
1. Harvard University – 100.0
2. Stanford University – 97.6
3. Massachusetts Institute of Technology (MIT) – 97.2
4. Princeton University – 97.0
5. Columbia University in the City of New York – 96.2
6. University of California, Berkeley – 96.1
7. Yale University – 96.0
8. Williams College – 94.1
9. Dartmouth College – 94.1
10. University of Notre Dame – 93.5
–=–
Oh, the conformists wet dream. But what happens when we consider these undefined terms of art by their true meaning? What happens when we actually define this word prestige?
PRESTIGIATION – noun – [Latin proestigioe, tricks.] The playing of legerdemain tricks; a juggling.
LEGERDEMAIN – noun – [See Light.] Slight of hand;a deceptive performance which depends on dexterity of hand; a trick performed with suchart and adroitness,that the manner or art eludes observation. The word is sometimes used adjectively; as a legerdemain trick.
PRESTIGIATOR – noun – A juggler; a cheat.
PRESTIGIATORY – adjective – Juggling; consisting of impostures.
IMPOSTURE – noun – [Latin impostura. See Impose.] Deception practiced under a false or assumed character;fraud or imposition practiced by a false pretender. —Form new legends, And fill the world with follies and impostures.
–Webster’s 1828 Dictionary of the English Language
–=–
What is a university but a clearing house of the victor’s falsified histories and instructions in fictional, artful things? What are they but government approved and censored agencies permitted to teach the acknowledgements of men, the synthesis of all things exposed to the filters of these institutions of that Hegelian Dialectic. Oh, how we have been tricked by the magical spellings and artful images (idols) of historical figures that sought only to defeat True knowledge attainment by the masses of illiterates. The dark light of the legerdemain wordsmith, scientist, and mathematician enlightens not the soul, but instead drives it into an adversarial state to stand against its own True Light and Nature.
To quote again, strangely enough, from my own upcoming “Volume II” of the “Strawman” book series:
“In etymology, the English word prestige stems from the word “trick,” taken from the 16th century French prestige, meaning “deceit, imposture, illusion,” and in the Modern French “illusion, magic, glamour.” From the Latin praestigium we get the meaning of “delusion, illusion” as is used for the adjective “prestigious.” Prestige was a derogatory term until the 19th century, where it was applied to Napoleon within the sense of his having politically a “dazzling influence” in 1815.
To be described as prestigious from the 1540’s was to be one who partook in “practicing illusion or magic” and was “deceptive,” stemming from the Latin praestigious as “full of tricks,” and from praestigiae meaning “juggler’s tricks,” which was likely altered by dissimilation from praestrigiae, and from praestringere meaning “to blind, blindfold, dazzle,” from prae “before” (same as pre-) added before stringere “to tie or bind” (as the verb to strain). Again, this was a derogatory term until the 19th century.
This notion of garnering state papers that show degree of education as a diploma (diplomatic papers) is comparable to the noun cachet, meaning a “seal affixed to a letter or document” from the 16th century, stemming from the Old French dialectal cacher “to press, crowd,” and from the Latin coactare “constrain” (cache). The French term lettre de cachet, meaning “letter under seal of the king,” made the evolutionary linguistic transliteration as a “(letter under) personal stamp (of the king)” to the modern word “prestige.”
A diploma is simply permission from the state to commit a certain degree of crime while acting in the states fictional (legal) persona; to take upon the surname a flattering title that would be unlawful to possess and profess for those not brainwashed by the syndicalist education monopoly.
In fact the etymological meaning of the very word education is shockingly defined from the 1530s as, “childrearing,” equivalent to “the training of animals,” from Middle French education (14c.) and directly from Latin educationem (nominative educatio) “a rearing, training,” the noun of action from past participle stem of educare (educate). The origin of education was as the instruction in social codes and manners; the meaning “systematic schooling and training for work” is from 1610s.
Let’s face it, all beasts of burden, including, as the U.S. Code repeatedly defines us, “man and other animals,” need to be trained for our place in animal husbandry and human trafficking under this human capital management system.
But hey, don’t worry, after reading this work you can always beg to be re-educated and placed back into the prestige of that fictional matrix of civil “life.” Just believe…
As for the intent of this institutionalized corporate structure of public education, it is to pre-strain an individual, meaning to limit knowledge to a particular direction or practice. The verb strain comes from around 1300, meaning to “tie, bind,fasten, gird,” from the present participle stem of Old French estreindre “bind tightly, clasp, squeeze,” from the Latin stringere meaning “draw tight,bind tight, compress, press together,” and also “to stroke, rub, press” with cognates from Lithuanian stregti “congeal, freeze, become stiff;” Greek strangein “twist;” Old High German strician “mends nets;” Old English streccian “to stretch;” and from German stramm and Dutch stram meaning “stiff“). From late 14th century it takes the meaning of “tighten; make taut,” and also to “exert oneself; overexert (a body part),” with the sense of “press through a filter,put (a liquid) through a strainer” also from early 14th century, while the meaning of “to stress beyond measure, carry too far, make a forced interpretation of” is from mid-15th century.
Ultimately, the university accreditation system is merely an authoritarian, for-profit monopoly that stands both as the barrier of true knowledge and as the forced source of officially bestowed permissive ability to participate or practice in most regulated commercial functions of government. The word authority, as it applies to the university school system, literally stems from autorite “book or quotation that settles an argument,” from the Old French auctorité “authority, prestige, right, permission, dignity, gravity; the Scriptures.” The Modern French autorité, from the Latin auctoritatem (nominative auctoritas), has the meaning of “invention, advice, opinion, influence, command,” from auctor “master, leader, author.” Most poignantly, this word authority from the late 14th century has the meaning of “power to enforce obedience,” and as “people in authority” is from the 1610s. Authorities in modern times was recorded as “those in charge, those with police powers” since the mid-19th century.
The song lyrics Teach Your Children Well comes to mind. For to have power over “education” by promoting the word-trickery of prestige over governmental institutions, this monopoly on knowledge can be retained by those keepers of mysteries in high authority. Oz can thus remain hidden behind a curtain of idiocy spelled out as a pretended history (his-story) in those prestigious text books.
The monopoly of education is dystopia.
Utopia cannot stand or thrive on ignorance.”
–=–
It is an amazing feeling to realize that the “professors” of “professions” are really just full of their own peers’ manufactured shit, corrupted to their capacity on the fiction of artful concepts and spoiled fruit from the fig-apple tree of worthless knowledge, being passed on to future generations just as it was “educationally” passed on to their animal selves. Imagine the arrogance it takes to accept a “masters” degree in anything taught by those who as well received their own “masters” degree from another manufactured “master” and so on. That a 23 year old “adult” can be awarded a certificate of “mastery” in anything is as ridiculous as the Mormon “Church” corporation sole assigning the flattering title of “elder” to 12 year old kids and doing so not in their christian name, but in their legal surname, totally against the scriptures. This is how flattering titles (names) are used, carrying no substance of the reality they formally represent (in artificial form/character/person/title), just as the clothes do not make the man. Mastery is a lifetime achievement, and one often recognized publicly only after the death of that master. A “Masters” degree, however, is currently on sale for $99,999. It is a name, a title, not a reality. Education, position, and status for sale; a devil’s contract of monetary and performance debt. To the cheater, to one raised to be a cheater and to summarily respect the prestige of university word magic and legerdemain trickery without question, it is par for the course that one should fallaciously flaunt a piece of paper sealed by the state so as to cheat even themselves out of ever Truly mastering anything at all, aside from their assigned and professed degree of crime and aptitude in their chosen, commercially professed fiction. Such professions are like invisible prisons for the mind, with humility nowhere to be found and where cognitive dissonance blossoms.
Likewise, to have a Masters in the English language is about as reasonable as having a prize for the most prestigious dingleberry in ones upper butt crack, professing oneself to a state-sanctioned mastery of what Mark Twain called the most “mongrel” language, a literalist word construction known also as “dog-Latin,” which was grammatically built for the purpose of mass public deception and illiteracy. The names of things we learn at 3 years old never change throughout our commercial livelihoods, for the metaphor and the parable is completely lost on the publicly educated, literalist English speaker, while their legal and “Romantic” origins reak havoc upon society. We learn the empty monetary value of all things by their names (nouns), but never the substance and essence of that which is enslaved by such artificial valuation and empty nomenclature. Strangely, we only know words by their name, not their substance or True meaning and Nature. And this explains the foundation of all our problems.
—=—
“So, we start with the question, now, as to why we cannot ask the question why? And that is because of the absence of knowledge of first cause… At school, for instance, we learn to liken words to objects. But even when we apply the word to the object, we have lost something. We have lost inner-meaning.We call things by the name. We say this is a “carrot.” And we therefore get a good mark on our examination paper. But what is a “carrot?” Neither the student nor the teacher knows, actually. It becomes merely a term to define the fact that we have accepted the language which we are studying, and that in that language, this particular vegetable is a “carrot.” But this does not tell us a thing about the “carrot.” It only divides it from some other vegetable. Why it is divided, how it is divided, what the life means, we do not know. But from the very earliest times, human beings attempted to find ways of learning the true meaning of the things which they classified… They made likenesses of the thing they were trying to discover or decide. And in this way they had a little more dimension than we get from words… Words have to be carefully considered and weighed. They can be the cause of war. They can result in riots. They can bring down the stock exchange in a bad catastrophe. They can do all kinds of things to us that we cannot appreciate or understand. And just as we are not permitted by law to injure other persons physically, we must sometimes realize that we can more profoundly influence and injure them verbally… Now,children today aren’t taught basic language. They are taught the names of things,and believe that (because) they have the name that they know the thing. So that if someone asks them, what is a “carrot,” they are apt to say “a vegetable,” and get the correct mark. But they don’t know what a character is, or a “carrot,” or anything else. They do not understand,but they consider the subject closed by the name. And the same is true in many different levels and developments of life. We give names to things, answer them according to their names, and consider that enough. This is one of the points that was made… in connection with education; the problem of finding out the names of things in terms of meaning. And the way to gain meaning is to recognize the basic vitality of the subject under discussion… In other words you have to be able to feel the facts of a thing, not merely listen to it and buy dictionaries.You have to participate in the experience of something in order to know it. And that was why such an emphasis was placed upon pre-school education. The problem is very certain that the faculties of true understanding have to be developed before schooling comes, or the schooling will be very largely rejected. We will finally end up with the individual memorizing the words and knowing nothing about the substance.So the person has to learn to recognize substance first.And the first substances of life are not learned in school, but in the pre-school period of childhood in which the association with adults or with others of its own age group, these result in certain basic experiences of like and dislike, of exception and acceptance and rejection. These things we gradually learn intuitively, then when education comes, we give meaning to words. Otherwise we give no meaning, and we just keep on using words without giving them any substance, essence, or vitality…“
“Historians, of course, use words to influence the reader. And it is generally admitted today that 90% of history is written by victors at the expense of the vanquished.And we always make a villain out of the loser, regardless of circumstances. So, we have all kinds of problems in history. We take the words; we believe them.But we don’t know whether they are true or not… We decide that the historian is correct if we agree with him. He is incorrect if we disagree with him. When in reality the facts of the matter are seldom actually considered.”
—Manly P. Hall, from his recorded lecture on “Language: the Use, Misuse and Abuse of Words”
—=—
Today’s “historians” seem to have been metamorphosed into bloggers and shock jocks on radio, news outlets, and newspapers, and as actors in Hollywood. Historical “facts” are delivered sometimes even before modern events ever happen. And so it is safe to embrace Mr. Hall’s perception that 90% of history, including that being broadcast and recorded instantly and live on the spot, is likely only the sponsored and paid for opinions of a powerful propagandist regime we call as our government. This model goes well with Huxley’s opinion that 90% of the population is quite hypnotizable in different degrees. No one seems to want to face the Truth that we are a morally, spiritually, and educationally defeated people. For that would mean inevitably that we are as well a militarily conquered people, and that our so-called government is actually the victor of this information war.
Fortunately in my own journey, my early research uncovered this design in totality. And I found that the definition of that word “conquer” actually carries the same meaning as the word “purchase,” and that the word “military” simply means thee entirety of the “Executive” enforcement branch of government. Let us not pretend that their money system, which no one can seem to deny, has certainly conquered us all. For the very industries that this government sanctioned education system grants degrees of crime and licensed (anarchical) diplomacy to are also the private and public stock corporations that government collectively owns through its international investment schemes. For it only seeks the most impressionable, hypnotizable of fools to fill with the most human of false pride those flatteringly titled positions of tenure and public employment. Only he who is most impressed and indebted by the word magic and prestige of their own paid-for educational experience will be accepted into bearing such prestigious flattering titles of professional and nonsensical conduct, bound in every way by their original performance debt of citizenship in agency to that principal government.
And so the reader should pay close attention to my much earlier, foundational research into CAFR’s, which shows government to be the main shareholder of ALL important and influential corporate stock through its non-governmental and pension investment schemes in all corporations around the world, especially in those pharmaceutical companies that have caused so much destruction of life and health in all nations and tribes.
To be clear, the regulator (government) regulates the corporations it owns through stock investment and indirectly votes (as collective shareholder) through proxy vote for the boards of directors, mergers and acquisitions, and other corporate governance issues. The regulator regulates its own corporate empire, a syndicalist domain of pure and utter “legalized” corruption. When government is the main or even partial shareholder of corporations as the design of “fascism” is said to be, and when the highest law of corporations is to protect its shareholders, then its oil companies are not made to clean up their spills and its pharmaceutical companies are allowed to lie to the public and kill in the name of scientific medicine in the name of profit and gain. And this is why primary research is so important, for they do not lie to government, only to us.
Of course, to be published one must cover up the Truth, which is why journals never do what we have done, explaining the entire cover-up publicly for full comprehension. When government owns through stock investment and voting powers the totality of mainstream media that, if it were actually independent, would otherwise criticize and report all aspects of the organized crime of government, then one should immediately recognize this conflict of interest and turn away from such an obvious propaganda outlet.
While Project Mockingbird is well known and even blatantly admitted on the CIA’s own website, we must realize that this sort of clandestine infiltration into the media is no longer necessary. For when government owns the majority holding of stock, it calls the shots by proxy. And those board members for which it collectively votes into each corporate boardroom certainly will not depose the hand that owns and feeds it. For the shareholders also proxy vote and approve salaries, raises, and bonuses for those syndicalist members of its held corporations.
But it is fun to remember when at least we believed the organized crime was on the outside, that it was imported into these media companies instead of being merely homegrown and quite expected and business as usual…
–=–
“You could get a journalist cheaper than a good call girl, for a couple hundred dollars a month.”
–CIA operative, discussing the availability and prices of journalists willing to peddle CIA propaganda and cover stories. Katherine the Great, by Deborah Davis
–=–
“The CIA currently maintains a network of several hundred foreign individuals around the world who provide intelligence for the CIA and at times attempt to influence opinion through the use of covert propaganda. These individuals provide the CIA with direct access to a large number of newspapers and periodicals,scores of press services and news agencies, radio and television stations, commercial book publishers, and other foreign media outlets.“
–Church Select Committee Report on U.S. Intelligence activities, 1975-76
–=–
“There is quite an incredible spread of relationships. You don’t need to manipulateTime magazine, for example, because there are [Central Intelligence] Agency people at the management level.“
–William B. Bader, former CIA intelligence officer, briefing members of the Senate Intelligence Committee, The CIA and the Media, by Carl Bernstein
–=–
“The Agency’s relationship with [The New York] Times was by far its most valuable among newspapers, according to CIA officials. [It was] general Times policy ... to provide assistance to the CIA whenever possible.“
–The CIA and the Media, by Carl Bernstein
–=–
“The history of the CIA’s involvement with the American press continues to be shrouded by an official policy of obfuscation and deception for the following principal reasons:
■ The use of journalists has been among the most productive means of intelligence‑gathering employed by the CIA. Although the Agency has cut back sharply on the use of reporters since 1973 primarily as a result of pressure from the media), some journalist‑operatives are still posted abroad.
■ Further investigation into the matter, CIA officials say, would inevitably reveal a series of embarrassing relationships in the 1950s and 1960s with some of the most powerful organizations and individuals in American journalism.
Among the executives who lent their cooperation to the Agency were Williarn Paley of the Columbia Broadcasting System, Henry Luce of Time Inc., Arthur Hays Sulzberger of the New York Times, Barry Bingham Sr. of the LouisviIle Courier‑Journal, and James Copley of the Copley News Service. Other organizations which cooperated with the CIA include the American Broadcasting Company (ABC), the National Broadcasting Company (NBC), the Associated Press (AP), United Press International UPI), Reuters, Hearst Newspapers, Scripps‑Howard, Newsweek magazine, the Mutual Broadcasting System, the Miami Heraldand the old Saturday Evening Post and New York Herald‑Tribune.
By far the most valuable of these associations, according to CIA officials, have been with the New York Times, CBS and Time Inc.“
“If even one American overseas carrying a press card is a paid informer for the CIA, then all Americans with those credentials are suspect… If the crisis of confidence faced by the news business—along with the government—is to be overcome, journalists must be willing to focus on themselves the same spotlight they so relentlessly train on others! …When it was reported… that newsmen themselves were on the payroll of the CIA, the story caused a brief stir, and then was dropped.”
“Over the past several years, the Bush administration has learned that it can engage the press in an adversarial way, and the public won’t mind. It’s yet another step in MANAGED NEWS…“
–Tom Hollihan, journalism expert at USC’s Annenberg School, from an interview on Christian Science Moniter titled, ‘Bush administration blurs media boundary’
–=–
“Senator William Proxmire has pegged the number of employees of the federal intelligence community at 148,000… though Proxmire’s number is itself a conservative one. The “intelligence community” is officially defined as including only those organizations that are members of the U.S. Intelligence Board (USIB); a dozen other agencies, charged with both foreign and domestic intelligence chores, are not encompassed by the term… The number of intelligence workers employed by the federal government is not 148,000, but some undetermined multiple of that number.”
–Jim Hougan, ‘Spooks’
–=–
“For some time I have been disturbed by the way the CIA has been diverted from its original assignment. It has become an operational and at times a POLICY-MAKING ARM of the government… I never had any thought that when I set up the CIA that it would be injected into PEACETIME cloak and dagger operations.“
–Former President Harry Truman, 22 December 1963, one month to the day after the JFK assassination, op-ed section of the Washington Post, early edition
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Now, how do you think this type of government infiltration of the CIA could happen? The answer is that no infiltration never really needed to happen. All corporations are government-created corporations, registered under the commercial protection of government, and the maxim of law states clearly that protection requires subjection. That goes for all subjects, all public (registered) citizenships (natural persons) and corporations (artificial persons). The government funded, floated corporate bonds, and over the years invested in the majority stock of all media and other corporations. The stockholders thus collectively and in consensus through private, non-governmental associations (NGOs) voted for the boards of directors of all those media corporations and in turn the governmentally hand-picked board of directors votes for their CEOs. And the conglomeration and monopolies formed since were simply government proxy shareholder votes pooled together for supporting mergers and acquisitions, as well as loose regulation and deregulation of such otherwise unlawful trusts.
Of course the CIA is the media. Duh!
This is syndicalism.
The regulator protects itself by protecting that which it has an interest in and which is also subject to its laws, never allowing the Truth to spill over in any comprehensible way for public consumption. And so when we out here independently without papers and pedigrees expose this stuff publicly we are made to appear like crazy nut-balls without perspective by those trained lapdogs, and our lack of syndicalistic “credentials” apparently means that our neutral research should be dismissed outright, despite the fact that all of it is the officially sourced materials of government unstarched for and thus unseen by the average person, as that which is never publicized in any revealing or talked about way. Most just pull out their imaginary copy of the constitution and beat it over our heads, pretending it was created for the common subject. More idiocracy, fro the preamble lets us know exactly who created the constitution and who its legacy is inherited to.
As George Carlin comedically but with all due seriousness and integrity stated:
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“The real looting in this country takes place in the transfer of the wealth from the poor to the rich… and the poor have been systematically looted in this country. The rich have been made richer under this criminal, fascist president and his government.”
—George Carlin
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What George didn’t mention is that “the rich” is merely a colloquialism for the bloodline, the private, feudal landholders, the family business, which is the commercial United States. Of course, the common people are still convinced that being a “white person” in law has anything to do with skin color, and that “Barrack Obama” is actually a black person. Silly rabbits, persons aren’t Real. Persons are words on paper. They have no “color” except the ink they are printed with. A person (legal status) is whatever government says it is.
Syndicalism requires both the compartmentalization and the character assassination of any who refuse their grant of credentialism, which includes the imaginary division of races. Never is the True nature information disputed, only the public’s perception of the messenger. Works every time… Hell, people still believe that David Duke is a member and Grand Dragon of the Ku Klux Klan and the Nazi Party, though almost forty years has passed since that affiliation.
Well then in full disclosure I must therefore admit, I once (and only once) went to a “witchcraft” coffee shop meet-up here in Salt Lake City because I was curious why so many covens existed here around the Mormon corporation, which therefore means I must be witch. But in context, I was interested in the fact that the “profit” (president) of the so-called church was born of Anne Hutchinson, a condemned witch in Salem, Mass, which was posted in a chart at their own genealogy center! Guess they thought no one would look at Mrs. hutchinson history, because now her name is magically vanished from that genealogy chart. Guess that’s what happens when you speak the Truth on local AM radio in the heart of Mormon history!
Of course, the only magic I saw was the miraculous disappearance of any tip for the barrister.
For those interested in the real magic that ails them through the magic wand of the vaccination needle, my initial research and construction of the prion plague can be found here, though most of our more recent research was exposed over the radio:
Patrick Jordon’s continuum of many books, including his latest “The Prion Agenda,” as well as many other sources can be found here: vaccinefraud.com
Examples of Patrick’s and my own many radio shows are linked below, where this evolutionary process through pharma-science “medicine” and the spread of animal and insect prions into the human body is exposed thoroughly. Note that the amount of research put into these shows represents both of our life’s work, and cannot be qualified in any other way.
Oh, and by the way, they are now aerosolizing prions, and my documentary shows why this is perfectly legal. Breath it in, baby…
But by all means, let’s keep ignoring this plague and its promoted delivery system as our friends, family, and eventually our own bodies are degraded and “evolved” (unfolded) in ways unimagined throughout all of modern history, except perhaps in some obscure genres of science fiction. And God forbid that the profits of the medical industry could be harmed by the consequences of such a disclosure. After all, the most profitable gains collected from the spread of disease is only in the treatment of the symptoms that the villainous infector causes, right?
Instead, let us keep doing habitually what the Laws of Nature forbid, polluting and cross-contaminating our bodies with the DNA and infected protein (prions) of every species on the planet through vaccination, including aborted human fetal tissue.
Even more insane, these infectious prions and their antibodies are available for purchase from several biologic companies. For instance, you can buy “GOATANTI HUMAN PEROXIREDOXIN 2 (C-TERMINAL)” here:
This biomedical madness is the thing true terrorism is potentially made of. It’s not even a black market, but quite in the open, where infectious disease and cancerous cells are showcased like whores in the Red Light District. It’s like children (elders) buying unlimited and unregulated candy at the local 7-11. And this anti-human prion plague has been transmitted to every vaccinated man, woman, or child reading this.
While this is just one example of what we have uncovered, sourced in triplicate after years of research collection and cogitation, it may help my readers in empathizing with my own frustration and profound sadness as my life’s research goes unheard and unheeded for lack of my own holding of any soul-eating syndicalist university credentialism. Of course, most of this hell on earth comes directly from that University system, where life itself is being patently (as property) altered (evolved) into some unique (novel) form and catalogued on behalf of government’s investment scheme in the genomic mapping horror film of all life… and subsequently of all that is therefore anti-life.
I explained in full detail, after months of intense research and contemplation, the very DNA of the education system here, how it works and why it would and should be immediately disrespected and dismantled… that is if any rational sense was left over in mankind after our minds have been “unfolded” by these human development and resource (slave) management corporations.
But who among us wishes to discover that our own diploma (legal, diplomatic papers) are only a sign and token of our own agentic conformity, acceptance, allowance, and syndicalism to this completely evil, totally government-funded, conspiratorial education system? Who wants to admit that education is to teach you what to think in a “profession” but not how to think or question its authority, causing one to be licensed and permitted only to profess what government compartmentally allows us to? Who wants to acknowledge that their bought-and-paid-for position of employment and legal status under a legal, flattering title of diplomacy and licensure under the legal state can only be accomplished by loving (believing) or at least pretending to believe and practice in the official story and history that every industry is built around? Who would give up their money, their pensions, their 401k, even when it is patently obvious that all one has was bought purely by filthy lucre?
Who among us that is “successful” because of their “education” and papers is willing to accept that the etymological meaning of the word education is “the training of animals,” the word animal meaning a “soulless” beast of burden or “domesticated pet?” Who wants to admit that their employment is slavery under contract, and that their moral will is decimated by that contract with the devils (attorneys) of those corporations?
Who wants to stand up against the grain to expose the Truth about their very own industry and artificial status (title) within it knowing that their funding and artificial, “professional” respect in that criminal syndicate and paychecks in mammon will be lost? No, it is better that billions suffer and die than to risk that scarlet letter of a true whistleblower.
Ironically, the reason I have nothing, the reason I am “poor” and almost destitute in material things is because I consciously and physically turned away from such false, flattering titles granted by the gods of the state. I turned towards the only Truth, the anti-fiction, slowly moving away from all artifice back into the True Nature of all things. I saw through the names and felt the emptiness of them. My own bought and paid for diploma is worthless for my lack of conformity and tribute to such syndicalism. I allowed myself to feel, to embrace the repulsion I contracted towards my own industry of choice, and to allow the responsibility of my actions to rest upon my own shoulders, not that of the artificial person (corporation) I pretended to be an “moral agent” (employee) of. I quit Hollywood. I quit entertainment. I quit propaganda. I quit making fiction that is adversarial to God and Nature, which in turn bars man’s enlightenment and replaces it with the darkest of false lights.
My particular story is here, a powerful and very personal testimony to the choices we all make and the evils that we pretend don’t exist because of our own participation and syndicalist self-interest in the world of legalism and corporations (artificial personhood). When our jobs truly depend on our being silent to such evils, then we are certainly consenting to and are in legal fact a willing participant of that evil.
Like so many out there still retaining some conscious awareness and still not plagued with pharmaceutical drugs, I used to think that I was somehow different, that something was wrong with me. I wasn’t “normal.” I could not fit into any part of this artificial matrix culture and commercially driven society no matter how much effort I put into the practice. I couldn’t stop asking questions and demanding answers. And so with every educational trade I pretentiously “mastered” I would ultimately cease in its pursuit as a career, recognizing its artful intentions as being purposefully and by design against the best interests of man and Nature. I could not control my sense of righteousness, my strict moral rectitude bounding from within, and thus my words would always get me in trouble as I expressed my True feelings and spiritual Nature in defense of the innocent. Among the Jews of Hollywood, this spiritual strength is a tangible death mark, a black ball, a self-sacrifice. For them, only goyim (voluntary slaves) need apply.
And so this was my journey, continuously uncovering the unnatural and criminal element of all things, both normalized and customary. It led me to join others of like mind, holding up signs and calling bullshit on everything around us, exposing lie after lie without remedy or solution, like a bunch of old men complaining about everything and everyone but themselves, pretending that there was some better time or system we must return to. But no such time actually exists, and all history is a lie. It is in fact this powerful but unprovable belief (faith) in some formerly unseen and better time that causes men in each new generation to never strive to achieve their own mutual perfection, always chasing the historical fallacy of their own tails of their forefathers without comprehension that they were already cut off and attainted at birth.
Below, I have accumulated the history of this last 10 or so years of my journey of discovery, evidential videos and articles of my strange path into the complete absurdity of legal fiction and finance and of the artifice of government. I have done this because, as this very well may be my last post on this blog and because I’m extremely tired and heavy-hearted, broken-hearted, I and am left wondering exactly what all this effort has been worth? Has it changed anything? Has it helped anyone? Have my heavy sacrifices all been in vain? And did I fool myself all this time into believing that I could change the world around me simply by uncovering the lies that surround our collective perception of what that world actually is?
I have raised about a quarter of what I need to raise in order to print in soft-cover book format the conclusion to my life’s work and research. I fearfully anticipated that this would be the case, seeing so many come into this fold only to never find the support of those who praise, criticize, and complain the loudest. And so I am making here one last case, one last cry out for help from anyone who has found value and attained before unknown knowledge from my many works and years of writing, research, and film-making. There are again over 1,800 subscribers on this blog, and the site has had over 1,400,000 views according to its statistics. My movies have been watched by 100’s of thousands, with “Lethal Injection: The Story of Vaccination” for instance having 147,000 views alone, not counting the many mirrored copies and DVDs I encouraged folks to spread freely over Youtube and other outlets, which now cannot be counted.
I am left in awe by the thought of even asking humbly for $1 from each of you in appreciation of the hours, no, years, no, a third of my adult LIFE that it took for me to comprehend and create those documentary films and to research and construct this blog. I marvel at what I could do if I was funded and had a platform unbound by financial constraints, a dream perpetually unrealized by so many like myself, who die the most miserable and unsatisfied men without selling out in conformity to such prestigious powers that pretend to be.
And so I am asking, in this final effort, that anyone reading this please donate what you think my work might be worth. If each reader that subscribes here donated $10 or $20, the price of 2 or 4 of those daily doses of poisonous Starbucks coffees, then I could preserve my book in printed form and hopefully begin a new journey of activism incomparable to this one. And to anyone that seeks a copy of this work once printed, I am still offering it as a gift in exchange for a gift of $30, sort of like a pre-order. It will be printed. The only question is whether or not I must go into personal debt AGAIN just to get my work out there for free!
So please, let me know that all of this was not in vain.
For those unfamiliar with all of my past works, please see all the videos and links below, an incomplete accumulation to be sure but still the strange story of my life and research.
There was a time when I could not have imagined becoming so sensitive in my awareness, that I could actually figure out “the system” and then actually possess the answers to almost every reasonable and even unreasonable question put forward to me. Now that I have reached that point, standing on top of a giant pile of clarified stinky-smelly crap, I realize why so very few arrive here while navigating that shit-storm of false dialectics and popular opinion websites. For to know the Truth one must sacrifice themselves to that ultimate and undeniable Reality, feeling its every pain and pleasure while suffering all the depressions and detachments that naturally must accompany such a transition, for a sacrifice without the purest of Loving intent is merely a loss, a slaughter. One must criticize oneself to no end, realizing and then shedding any fictional notion of legitimacy in ones own employments, status, estate, and memberships. One must despoil any prestige one might profess and pretend. One must Truly take off all the make-up and clothing, all of the false and flattering titles and impressions, the false show and dressings, the pomp and circumstance, so as to finally see oneself in and only as a True Light. It is not as easy as looking in the mirror, for that reflection is always false, 2-dimentional, and without soul, Source, or sense. One must find oneself without such artificial means, no longer seeing without understanding and hearing without listening.
The Truth is not salable. It has no price tag. It cannot be valued in anything but what is the priceless Reality of Nature. Self-evident, Self-Existent Truth is timeless and always defensive, never offensive. It harms only lies and the liars who live by and trust in them. It needs nor requires no debate to Exist. The Truth may only offend fiction, lies, and false beliefs, all of which are offensive to the Truth, and all of which make up a citizenship.
The so-called “truth movement” doesn’t practice actual Truth-telling, for that would be unprofitable. It would require ego-death. It would require admission to our own volunteerism and use, which makes the commercial world go round. Even the principles (maxims) of law legally allow lies to be confirmed and ratified (legal) truths; for black to be white and left to be right, so long as that truth is constituted, contracted, confirmed, ratified, and made “legal,” then believed in (loved) and lived by in the performance debt of membership (citizenship).
Government can lie to the public, but the public cannot lie to government. This was the recent “excuse” offered in support of Hillary Clinton’s lies about her emails to the public.
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“There’s no particular penalty for lying to the public, unless the public get tired of it. But there’s a real penalty for lying to the FBI.”
—Senator Mitch McConnell, speaking on the known fact of Hilary Clinton’s lies to the public about her emails in 2016, speaking honestly to the public on CBS news
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Remember, it is perfectly legal for anyone to lie to the public, including myself, Alex Jones and the rest of the mainstream (pretending to be alternative) media. Fox News even reestablished this fact in court! When your own senator comes out public to reveal that there is no law or sanction (punishment) for government (including a future presidential candidate) to lie to the public, how do you go on supporting and being a subject of that government, of that kingdom and its kings of lies?
Here’s an example of why corporations and agents of government have the right to lie to the public as “free speech” of “artificial persons,” but why “individuals” or “natural persons” (an oxymoron) can never lie to government (owner of the public persons/titles/statuses) we pretend to be.
“Associated Press | LOS ANGELES (AP) — Minutes after former Los Angeles County Sheriff Lee Baca acknowledged failing the public by lying to federal authorities investigating jail beatings, a judge overseeing his corruption case shocked a packed courtroom by rejecting the ex-lawman’s plea agreement as too lenient.”
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But what about the news agencies themselves lying to the public? As long as its not a lie told to government, anything goes…
Watch this:
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But “Infowars” would never lie, right?
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And to understand just what “ethics” is in government, and how the legislature actually has no watchers, but instead judge each other in their organized crime, see my expose here, which includes how much they pay themselves. I guarantee once you finish this article you will have no doubt why no actual ethics exist in government.
The “truth movement” does not preach to its listeners the virtue of being (living) at all times in the Natural Truth (within only Nature and under It’s Highest Laws), for then no one would be glued and listening to a damned artificial construct and machine receiver as if it were Real. No one would attach themselves to this fictional, illusionary, virtual online matrix, and would instead embrace their very own Nature and their place within it without such artifice and useless information. The war would only be to keep such information from being spewed in replacement of spiritually driven knowledge. Just as the Church never teaches the True poetic and parabolic verse of the Bible it claims to support and worship, political writers in their prose would never be paid and talking-heads would not be amplified if the subject was what the only self-existent, self-evident Truth actually is. I am a living testament to this fact. Stations and networks would collapse under the weight of deaf ears as we all went out to rediscover the calming frequencies of that uneventful silence of Nature again, the sounds of the True Design of Life uninterrupted by fictional and monetary considerations. Youtube addicts would recede from their electromagnetic programming waves in dark basements and seek instead the tides of the oceans, sunny beaches, and vegetable gardens without commerce. Youtube would be replace with you- topiary. No one would allow themselves to be employed (used in agency as a tool) by another ever again, working only the land for themselves and toward the enrichment and nurturing (True wealth) of all others, realizing the most important Truth that labor is property, and that methodically trading it for money is voluntarily a surrender to evil geniuses (devils); to men with contractual, corporate, artificial power to take what we so foolishly and willingly give. For we would realize that even as new forms of money are promoted to us by such outlets of supposed truth, from gold to “Bitcoin” to the already developing international cashless society of global commerce, that all forms of money require respect and love (belief in) the valuation of that form of money upon all things, that Life and Nature itself can be valued in money, and that money or what it is traded for is never the property of the petty user. To love the pretended substance of money when in Reality it exists only in empty form is the root of all evils. This is the only Truth about money, for that which is not of self-evident Truth cannot ever Exist in any permanence of foundation, but rather only in a purposefully and carefully controlled chaotic flux managed by its demented patenters. For though all things may be valued in money, money is always valued in nothing. This is a maxim (principle) of law. What is valued in money is always corrupted. It is the valuation of the name, the form, the use, and the insurable appearance, but never the substance, the source, and the soul. This is mammon…being not merely that specific tool of money, but the artificial valuation of that which is the priceless, timeless wonder and beauty of Nature. The turning of Source into re-source, including governments corporate structure of commercial human resource management that we call as public citizenship but which is really modern feudalism. Only a slave romanticizes his own enslavement. Only a slave worships and even votes for his next master.
Nature and all life within its realm is priceless, but it may be destroyed when the valuation of mammon is placed upon its bounty, and thus by the mercenaries (soldiers for hire’s) hand it may be sacrificed in pointless slaughter for a price and without Love and respect for its Laws. The soldier is like any other employee in contract to do as his principal instructs and pays for. Of course, the word soldier comes from the Latin word solidus, which was a Roman gold coin. A soldier is a mercenary for pay. There is no other Truth. If that somehow offends you, then you must consider that the undeniable, self-evident Truth offends you. And you may then continue consciously lying to yourself. Pretend all you want that these men aren’t induced into contract with the state to kill and given bonuses, benefits, pensions, and a paycheck.
In the so-called truth-movement, the worst kinds of men are celebrated as “true” heroes. The beauty of finding the only Truth of the Nature of all things is that no longer can words, names, titles, and actions like cold-blooded murderer for pay be twisted into some governmental and propagandist actuarial report and then claimed to be an act of honor. A killer for hire has no honor, even and especially when he is wrapped in the American flag of maritime commerce and war. Give me a militia man fighting for his and his like-minded neighbor’s homeland, family, and spiritual freedom from government without consideration of money and I will show you all respect for that man’s actions. But, as the Bible continuously warns, I will never respect any man due to his false and flattering title of authority, nor his actions taken cowardly there under its artificial persona and protection. There is also no excuse to break the Highest Law of Nature, especially the excuse of that root of all evil and the authority of men in false, fictional, legally flattering titles.
But then, I would need here to show you my huge research project called Cracking The Cult Of The Constitution, perhaps some of my most important work, before this patriotic nonsense and support of that which domestically enslaves us under the Leiber Code could be broken. For a civil war is a war of words, names, and titles, not of men. And the American civil war never ended. I’d have to show you the congressionally confirmed and ratified presidential dictatorship that is the Executive CEO and CIC (president) under emergency military rule before you could see that our military is occupying our civil society and protecting government and its private, landholding bloodline from the multitude of us:
What use is all the gold and oil in the land when the land itself is becoming so polluted and useless that no amount of money can be used to fix it? What use is money if it is not being used to ensure the wealth of all others and to protect the Source of our very own Existence and best interests? What is money without equitableness, without adherence to the Natural Law that forbids such accumulation of wealth beyond need or measure at the expense of all others?
The only Truth about money, the only final winning argument in any monetary debate, is the simple and obvious self-evident conclusion that money is not Real. It is not of Nature; not of Source. No matter how you may cleverly try to justify its existence and its use by some pretended, always fluctuating, temporary value made up by bankers in their own fictional realm, its value can never escape that fictional realm. It is not money that money is evil, but the love (belief) it causes in men to value all things within its purview, even other men as purchasable slaves. This is the temporary power of mammon (valuation) to cause permanent, controllable insanity in “civilized” men.
I believe it is time for me to step away from this nonsensical movement and its pointless, fruitless debates and platforms, a propaganda machine in and of itself that promotes the waving of the national flag (and its law of the sea) of a district of pirates that has kidnapped and interned us all through birth registration and certification with the intent to cause escheat and steal all of our inheritable land. Yet we worship it as if it were a god, even above and totally against the Word in the Bible, the very essence and foundation of the common law. It’s design is to fictionally, “legally” corrupt our blood so that we may never be the prodigal sons we are bloodborn to be. We may never protect the lands of our ancestors, for no heirs are recognized by law, by blood, for no one is being born outside the trappings of the imposts of that national system and district. That which is artificial has no blood, thus he who is surety to some United States person (legal status) certainly has no blood right.
The United States is a horrific corporate machine where the “Made In America” symbol and flag is shamelessly placed upon slave-labor products made in its own federal prisons. Yet no one seems to mind or complain. It is a commercial black hole that promotes legal (artificial) liberty while in reality only offers a commercial franchise called a national citizen-ship that is denizened and so voluntarily incorporated in agency, barely one step above involuntary slavery.
I see no point in documenting the corruption of this strange society in its purposefully induced ignorant state any longer, for the crimes of its agencies and practitioners are never punished, only talked about and loosely recorded as “truth” in the buttcrack of some conspiracy website. The so-called “infowar” is just what its title exclaims it to be, a battle to put worthless, fictional information into each of our collective heads in a total abandonment of God’s Law and Nature. And yet nowhere in all of this supposed truth-telling (convincing us that black is indeed white and left is surely and legally right) are to be found the Laws of Nature, the moral and spiritual Laws that defeat the false powers and corruption of information and mammon, showing it to be merely the artful renditions of the tribe of the name (noun), as fictional persons (corporations), places (legal jurisdictions), and things (property). All of Nature has been re-named (nouns), and so all of Nature has been fictionalized and registered (taxed) by its name (information). The Infowar is not a charitable and loving action of men, but exists only as a for-profit corporation; an artificial person seeking gain by the spread of the useless information of the fictional designs of men. It’s talking heads cannot save you or I, for the only savior is each of our True Selves in our own actions (works) under the Natural Law, under the example of christ. And only the unattained True knowledge of what is the self-evident Truth of Nature both realized and uninterrupted by fictional concepts of the fruit of the tree of conceptual acknowledgement of good and evil will solve any fictional problem. There are only two issues, what is Real and what is artificial (art) posing as Reality. The solution is so simple it hurts, for it is merely to stop respecting art over the Reality it legally, artificially represents. In a nutshell, this is all the scriptures teach us, which is why the church doesn’t ever teach the Bible but instead its own doctrines that justify its corporate existence against the Bible.
I wrote about this strange time we live in, calling it The Great Disclosure, wherein corruption and greed are coming out of the closet and avoiding all consequences, thanks to the information fad. For knowledge of evil without action against it is acknowledgment of evil. Silence is consent. Inaction is the greatest of sins. The word sin (syn) means to be with anything. To be unopposed in our actions is to be in syn-thesis with it, to be in allowance and toleration of that evil thing. This is the state of the “union,” a common people standing with its government no matter what it does. A nation of syn (sin).
And of course none of this would be possible without the advent of social media, a virtual matrix designed for this very purpose, to disseminate information without consequential intent.
Along the way, as all this nonsense was rearing its ugly head for what it is, I began to study the words of this legalistic system of commerce, find words like redemption and being saved attributed to money, the god of nations in trust to mammon. I sought to find the True and Natural Law meaning of these words, knowing that no redemption or solution can ever be found through the emptiness of monetary inducements. And so I began in my first real effort to compile and decipher the words of King Jame’s purposefully misleading English (dog-Latin) translation of the Bible, witnessing how the legal language is a matrix code standing in substitution and artificial representation of the Bible code (Law). To this end, I compiled Cracking The Legal Code Of King James:
Hell – The name given to a place under the exchequer chamber, where the king’s debtors were confined. Rich. Diet. (Black’s Law 4rth Edition) (Balentines Law, 3rd Edition)
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What is citizenship if not an open air prison for debtors? Same system, different name. Wrap the American flag around it and you have yourself a party in hell for patriotic debt-slaves!
Let us be clear… this alternative media disclosure of information is not an awakening, and this religious notion that “truths” and “patriots” are woken up is pure nonsense. To wake up from the American dream (nightmare) is to fall hard back into Nature, into what is Reality. Political and monetary “knowledge” is false, and is not an awakening, especially when one still participates in that which he has supposedly woken up from. Don’t kid yourselves. This information war and disclosure without consequence is merely an admission of organized crime, of the lies of liars, where the criminals continue unabated despite such disclosure. Information awareness causes informed consent at best, complacency and apathy at the worst. And the best place for criminals (devils/attorneys) to operate is out in the open, where their deeds are seen, known, and accepted in the light.
Thus our “choice” for president is between two criminals that have outed each other as the liars and criminal element they are, pretending all that information is null once the fictional campaign reaches the primary. There is no choice, for a True choice would include “NONE OF THE ABOVE,” not merely a pick of two or more evils. And if you do not vote, you still have made a choice. Disclosure of information is certainly not a cure for the disease, and in fact it promotes the disease by promoting the perceived helplessness of those who absorb the lies and crimes without taking action. This “infowar” is not for the purposes of lawful prevention but of mass-programming, a manipulation of the publicly perceived normalcy-bias of we, the public-minded commoners towards acceptance of that openly organized crime syndicate, which is merely business (commerce) as usual. Even the devil pretends to be as the light, and uses the legal system and law to flatteringly title himself as such. In legal land, satan is God. Lies are truth. Dark is light. Slavery is freedom (franchise). Perpetual war is peace. Fear is happiness. The God of Nature is dead.
And the patriotic course is of course to seek remedy and solution from the very source and protection racket of that syndicate, the court system, by finding some imaginary trust and investment scheme we can all tap into. Money is the savior, a compensation for being tossed into this debtors hell. Perhaps its time to raise the “bar” a bit and stop seeking justice from corruption and salvation from artifice in mammon?
A quick browsing of the Infowars website reveals nothing of the spirit, nothing of the True knowledge, merely more fruit of the conceptual tree of good and evil. And the “fans” eat it up, for a scholar and even a half-way decent researcher could not help but to find eventually such informational “truth” to be mostly false, opinionated fear mongering designed to sell products specifically tailored to novel fear sales campaigns. At the website we find threats of impending doom via yet unrealized events such as “World War III” along side advertisements for survival products and guns. We spread the fear of nuclear weapons and the Fukushima radiation hoax if you are not trying to sell the besets, top quality, high performance, ultra purified, super-duper, fuck yeah iodine supplements at the same time? Fear and sex certainly sell, and Mr. Jones certainly ain’t too sexy for his shirt, having a face special ordered for radio. His Zionist ex-wife insists on what a “good actor” he really is though.
And so fear is all he can peddle while promoting what he used to preach against, his “info-babes” and graphic backdrops. Most new Infowariers (fans) never saw or choose not to remember when Jones reported over a decade ago on the info-babes of Fox News and other mainstream outlets, with their bodacious ta-ta’s hanging out while they reported the so-called “news.” Now he’s promoting it. They don’t remember or choose not to remember when Jones reported on the graphics and satanic studio mnemonics that were flashed all over the mainstream screen and logos. Today, Jones uses similar mnemonics as his background graphics. He promotes christian values along side free-market capitalism, as if money (mammon) and commerce was ever a value put forward by christ. He reports on the enemy (our government) while waving its national flag of nativity, never teaching the difference between territory (land in Nature) and nationality (fictional hell). The Infowars site continuously promotes idiotic protests at the Republican Convention, not for any reason but that they are easy prey, easily picked apart, guaranteed to produce usable media footage of rebels without an actual cause or clue, and easily instigated by Jones to cause a small riot.
But then, one must ask exactly what is the purpose of this self-titled “infowar” if not disclosure without consequence, considering that nothing has ever been changed or corrected that is reported there, that no prisoners have been taken, nor any battles won because of that non-vetted, Youtube created, totally illegitimate and outside of the custody-chain of legally accepted evidence and at best third-party “information” that is never going to be acceptable in any legitimate court of law. But it’s all apparently good enough for the fools who support that info clearing house, for those who are caught up in their own info-prison-planet paradigm.
And so we search and find at these information sites only feul for the fire of informational consumerism and manufactured consent, creating an “informed” audience that actually believes they can prepare for modern warfare and zombies with the same outdated weapons, guns, and ammunition that their own government unlawfully traffics openly to all of its third world enemies in foreign countries without fear of those now primitive weapons compared to the fourth and fifth generation warfare tactics and weapons of today. Might as well be sticks and stones, but the infowar sponsors will sell them to you for much more than they are worth! To be informed by Infowars is like being an expert in video games, having knowledge only of the foundations of fiction and virtual reality while having no ability to survive the winter without government subsidies and on-grid benefits. But the games are played on government owned and militarily occupied fields and municipalities, and only with governments permission.
And so, naturally, we find more paradoxical behavior there in Jones’ paradigm support of a presidential candidate that represents one of the completely private associations (artificial persons) called the “Republican Party,” despite the fact that Jones claims himself to be “Libertarian.” (I suggest doing a search for “libertarianism and satanism” and see what pops up as to who created that political ideology!) But wait a minute! What happened to the left-right paradigm, Alex? When did Infowarriers become part of the right against left fiction? Turns out paradoxes can exist after all!
And yet nowhere do we find the Truth about these presidential elections, which is that the common people Jones preaches his disinformation to do not even elect the president. Voting is not, after all, electing. Two different words there. Having covered this subject and how the electoral college elects the president so many times here on this blog, we find this particular Truth avoided so that the dramatic story of the “rigged election” process may unfold and be repeatedly told to sell more products to support the infowar, just as it is in mainstream news outlets; inducements for readers and subscribers to purchase more worthless “health” and “survival” products to support the infowar paradigm. Why would the very man who coined the phrase “left-right paradigm” support the right against the left, when we know its all the same team? Because both of these candidates are his bloodline, Clinton and Trump standing united in blood but divided for public show. How many times do you need to hear Ales Emetic Jones speak about his bloodline relationship to the “People” who founded this nation before you realize that Jones is on their side, and that their side is opposed to yours?
It’s the same old story, as every president including the “white person” renamed “Obama” of the white (Jewish) Dunham clan of landholders are proven to be of the same line. And the opposing candidate is always a cousin. It’s always a choice between family members.
I spent a whole year researching and collecting genealogical records, becoming an addiction towards the end, and discovering a hidden class that can only be compared to the movie “They Live” running the entire political, corporate, and religious show:
As many readers have difficulty comprehending the bloodline issue, though EVERY OTHER COUNTRY IN THE WORLD is inherited by the heirs of the blood, here is my earlier compilation of research, with many links, along with an over 4 hour radio presentation on the subject accounting for months and months of research into the subject.
And of course, when we truly see beyond the vail of that left-right paradigm that the Infowar has apparently and conveniently forgotten about, we see that the Republican Party is merely the Democrat party in disguise…
But the Real Truth is that we are battling only ourselves like pawns on a chessboard, for we are participating in and respecting nothing but fictional events (the history of fictional persons, places, and things) on the Roman calendar. We romanticize everything until its actuality is indistinguishable from its embellishments, and we call it the truth. We lend credibility to such artifices as elections, in turn giving them a false sense of legitimacy (truth) as we lust after our own franchised stake within it. Yet we never seem to notice that there is no box to check NO. Choose is yes or no, not Trump or Clinton. But the illusion of choice is certainly baked into our brains by the infowar, making this causality of a certainty of two evils appear as if “the people” in common have spoken. And the billions spent in media and advertising keep up appearances though the modern feudal system never changes. It cannot change, for it is built (constituted) into the very law we foolishly and ignorantly respect. And the bloodline always wins every election, even as these latest of two cousins by the same grandmother pretend to compete with each other while promising their feudal tenants change we can be made to believe in. Of course in technology circles (i.e. artificial information), the word “change” comes from the word “delta,” which in the Brave New World model are the working class of slaves to the Alphas and Betas, not quite bright enough to see their designs and content in their institutionalized feudalistic form of happy slavery. OF course, only a slave votes for a master, and only he who has turned away from God seeks any such artful master.
The infowar’s greatest design is to cause all men to suffer each other’s collective inaction. It puts us all into our own form of artificial political party, with leaders more corrupt than those it exposes for profit. The group mentality, above all else, is pushed therein. And so as long as it appears that the group, the subscribers, the membership is waking up due to such a randomized oil spill of informational nothingness by the “truth party” leaders, individual action is thwarted, even as personal power is cowed by that prison of mental programming.
As to the only True power any man has, I decided to examine and re-write my own individual declaration of independence, with a comparison of current events and power structures that so far surpass the original that its authors would be ashamed to call us their sons and daughters. As long as we collectively toss our personal power into a group setting and then allow that group mentality to decide for us how our personal power should be utilized, we might as well admit that we are individually powerless and that our will or God’s shalt never be done. But its easier this way, right? Easier to just go with the flow, to grow with the seeds of corruption planted for us as our own garden (prison)?
For that theft of personal will and power is the Real power of political parties. Apparently “infowarriors” are “republicans” this time around, and the True nature of that political party paradigm be damned as they collectively support this current, prestigious representative of the bloodline despite the cognitive dissonance they must be feeling.
The harshest and most outward Truth is that most people in this war of information do not seek the Truth, for the Truth would actually set them free into Nature, taking them out of their security of legal franchise in personhood (legally granted and enforced “freedom” under dominion of the landlords), and the illusions preferred by such an information matrix as a virtual reality is much easier to accept than facing the Truth without such insurance and security of the church and state. For the Truth is only what is Real, what is of Nature, what is self-evident and self-existent, and therefore it is only what is not a fictional creation and invention of mans imagination. In this way, what we call as the agreed upon legal “truth” of information can be blamed for our own actions and inactions, allowing us to ignore our responsibilities to thwart such evil (artifice) and lies. And we get the added bonus of this imaginary enemy, the invented cause of all of our problems, as we pretend that we have no choice but to follow our leaders. We scream for a “voluntary society,” ignoring in an almost institutional way that all of our actions are in fact voluntary, and that participation in legal, contractual citizenship is certainly, under the doctrine of volunteerism (master and servant), a voluntary state of artificial being.
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“The rights of the individuals are restricted only to the extent that they have been voluntarily surrendered by the citizenship to agencies of government.”
—City of Dallas v Mitchell, 245 S.W. 944
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As the song goes, “No one can take away your right to fight and to never surrender.” But ask any anarchist for their excuse for volunteering and following the legal law in personhood is because if they don’t they will be harmed somehow. Some even claim there is an imaginary gun to their head 24/7, that all services are provided by government with a gun forcing them to partake in it. But the Truth is that unless you are willing to die for what you believe in (love), unless you are willing to kill to protect your beliefs (loves), then you are just full of shit. Citizenship is a surrender of unalienability. It is a turning away from God and Natural Law. There is no excuse before the God of Nature or before a magistrate judge (legal god), for ignorance is no excuse to break any Law, including Nature’s. Pretending that we are not voluntarily participating in the adversarial evils of legalism doesn’t make it the Truth. You could fight, you could never surrender, but then your licenses and privileges (franchise freedom) might be taken away. It’s time to grow up and stop lying to ourselves that we are being forced. It’s a self-decieving lie built of fear and spiritual uncertainty and nothing more. No one can take away your right to fight and to never surrender. Fighting and surrendering are always voluntary acts. And no one is ever forced to be in public citizenship (voluntary servitude).
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“So, we have all over today all kinds of cliques and clans and sects. We have anarchists and activists all fighting, really,over the same thing.All actually missing the point; missing the real point of the whole thing, being that, Truth makes peace; error makes law. If the individual understands the facts of his own faith correctly, he will discover the faiths of all others. But if he becomes merely a bigot of his own, and intolerant of all that he does not believe to be true, then when he attacks the other persons belief he is only attacking his own belief under a different name.”
—Manly P. Hall, from a recorded lecture on “Language: the Use, Misuse and Abuse of Words”
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And so instead of unvolunteering we instead demonize that which we in fact continuously volunteer to support. We vote for our masters even as we call them criminals, which can only really mean that we get what we deserve. And if we do not vote, if we do not make a choice, and at the same time still volunteer to be subjects of government in citizenship, we still have made a choice, the choice of the actual electors in a rigged election. We go through these motions even as they call themselves as the worst criminals in their political, primetime debates. We allow them to steal from us because it is voluntary and legal according to their own legislated codes, through taxation and other forms of exaction and extortion. For while contracting and acting in U.S. and other national, commercial citizen-ships (vessels) is easily proved to be a voluntary commercial franchise (legal freedom), the law applied to said citizen-ship is not voluntary. For as the maxim (foundational principle) of law states, to know the law and to be bound under the law are the same thing in consideration of the agents (judges) and creators (magistrate gods) of law.
For instance, since the principles of law also state that ignorance of law is never an excuse, ignorance of this completely feudal part of the U.S. Code is no excuse for any man participating voluntarily. You better learn real quick that these are your rights when voluntarily acting in the person of the nation (district)!!!
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42 U.S. Code § 1981 – Equal rights under the law
(a) Statement of equal rights
“All persons within the jurisdiction of the United States shall have the same right in every State and Territory to make and enforce contracts, to sue, be parties, give evidence, and to the full and equal benefit of all laws and proceedings for the security of persons and property as is enjoyed by white citizens, and shall be subject to like punishment, pains, penalties, taxes, licenses, and exactions of every kind, and to no other.“
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EXACTION:
“Torts. A willful wrong done by an officer, or by one who, under color of his office, takes more fee or pay for his services than what the law allows. Between extortion and exaction there is this difference; that in the former case (extortion) the officer extorts more than his due, when something is due to him; in the latter (exaction), he exacts what IS NOT HIS DUE, when there is nothing due to him.“
–Bouvier’s Law Dictionary, 1856, commissioned as an official dictionary of congress
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Exaction (the worst kind of extortion) is your legal right, like it or not. It is an executively enforced right of personhood. And every citizenship shares that right equally. It is a requirement of every public citizenship. And though we complain fervently about such extortion as taxation and “fees” and “penalties” as exaction, we never seem to acknowledge the fact that the U.S. Code states clearly that it is our enforced and involuntary “RIGHT” to be exacted, taxed, put in pain, punished, exacted, etc. And we pretend that we have free speech as we complain, even when we are writing out our checks to the IRS and other agencies of government, fulfilling our right to be exacted from and giving agencies and their agents what is not their due, just as the kings and publicans (tax-collectors) of old. Rights are voluntarily accepted as mandatory in exchange for allegiance and submission to all other laws and the benefits and protections they afford. This is well established as a maxim and foundation of law. A right granted by any person, place, or thing (legal noun/name/title) is not a self-existent, self-evident God-given Right. It is not unalienable, but rather requires the lien of surety bondage of citizenship. It is contractual. And contracts are always voluntary, though their terms are restrictive and enforceable. The devil can only defeat a man of God with words, and citizenship is nothing more than a legally binding contract – a performance debt.
The Truth of Nature is now being customarily augmented just as much by Poki-mon monsters as it is with the lies of attorneys, politicians, and priests. And all media outlets are there to keep us interested, attached, and plugged-in to the information game. To pretend to be on the alternative or pretended truthful side of information is no different that being in on a lie. To pretend that alternative news is anything but information about confirmed and ratified lies called as legal truths is the first circle of hell. And to argue over what is good and sound money practices is the foundation of hell, a worshiping and respect of mammon and its artificial matrix of monetary valuation. For money can only be justified if slavery is justified, if everything in Nature is assigned a legal name or title, and the name is valued in mammon, taking away the True Freedom of all Life and Source, turing God’s Creation into a re-source of man. Only then is a valuation placed upon the priceless Nature of self-existence. And this is the harshest Truth of all. For one cannot Truly take sides in a “war” over information, for all information is merely coded and organized words, never actual Source. A war of words (information) will lead to nowhere, yet has the potentiality to cause men to destroy all Life so as to fulfill that war. Only then can the infowar be won, for there would be no beings left to distill and distribute such artificial things and words. The info would die with its source, mirroring the death and finally decayed madness of unspiritual men. Fiction may only destroy man if man allows fiction to rule his mind. Man may only destroy his own Nature if he continues to fall pray to this war of artificial information.
Perhaps the most painful Truth to finally comprehend is also the most obvious and ironic one. For there is a very good reason that the infowar stays only in the info (legal fiction) realm and never in the realm of action, a reason that is self-evident when the question of what is government finally becomes clear and is able to be considered by men bound to the Natural Law without vain patriotic accouterments in support of fictions and legalistic laws and licensure. The infowar stays out of the courts, out of the legal system, because a judges’ (legally entitled artificial person’s) first duty is to protect its principal employer, the very government it represents and holds its authority in flattering title from. In other words, no judge will rule against government or its members and sovereign magistrates or “People” because no judge can put the United States in harm’s way.
The judge protects the government from us, not us from government. No decision that would, for instance, cause rioting in the streets will ever be opinionated in any majority or precedent-setting ruling, unless that is the desired goal in order to cause more heavy-handed executive agencies and legislation. Organized crime will never rule against its own syndication, against the very incorporation that gives it its own false authority. If the nation wishes to have civil war, it will have it. All it needs to promulgate is the proper false information to its unwitting citizen-ships, the vessels of commerce that do not recognize their own voluntary enslavement and servitude.
And so obviously the events of 9/11 will not be pinned on government as an “inside job” by the very magistrate judges that corporation nation employs! Duh! How many countless hours do so many “truthers” expend delving into the actual events of September 11th, 2001, as if nothing else happened on that day? How much energy is put forward in exposing the information of that “event” without ever actually doing anything about it? How many criminal connections have been made to the very politicians in office at that time, and how many of them have been executed for treason or been placed in jail or banished? The infowar ensures that only information disclosure but never action takes place, as if we are sitting in an imaginary coliseum cheering for the sign from Caesar to punish or kill the gladiators. But Caesar is the District, and it will never give itself the accusatory thumb. It judges itself, for its judges are gods, and gods can only exist through nations.
I guarantee you that the end of this road towards the discovery or just what is Truth does not end with any .com,.info, or .org title, and especially not with a .gov disposition. When one finally sees only the Truth and knows it instinctually and as totally distinguishable from artifice, it is always recognizable and cannot be mis-taken for anything but It’s own Nature of self-evidence and self-existence. For it is Pure in its Nature. It is all aspects of True Existence; a Oneness that Exists despite man’s names, titles, numerals, or symbols used to fictionally define It. And it is only when the Real outweighs and crushes any artificial valuation and name (noun) placed upon it by man that one finally sees the Truth.
The only question that remains is how do we Live only in Truth, in only our spiritual Nature, without the pretended power of that artifice of informational nonsense?
As for myself, I remember fervently debating over the concept of “sound money” for many years. The word sound carries the meaning of stability, which money by design has and can have none of, except in its ultimately temporary life and valuation, which is always in Truth an absolute nothingness. Its value is only as sound as the sand running out of the hourglass, for like the hourglass, money is merely a design of man’s imagination. Money is nothing more than a belief system, a religious faith in it as a god (creator), not a self-evident Truth. It is a creation of man, not of God’s Nature and Source, and so it can never exist in self-evident Reality. What is money today may be fuel for a depressive or inflation fire tomorrow. Money of yesterday is used for wallpaper today, if it is not worshiped vainly as somehow more artificially valuable than its face once re-presented. Tomorrows money will be touted as the cure for todays monetary dis-ease, though like any pharmaceutical remedy it will only replace one dis-ease with another set of symptoms. And these new symptoms will be compounded as the new name of the same old dis-ease in that perpetually mind-numbing monopoly game of mammon. Money, you see, is also merely empty and falsified information. And that’s why, like the priests of all denominations of disinformation-spewing, legally incorporated churches, the Infowar corporation seeks money in everything it does. It’s an information exchange network. It sells lies told as truths in exchange for the biggest and most brilliant lie of all, that of monetary wealth.
What is sound is what everything should be built upon. A foundation. When a society’s foundation is built upon money, upon commerce, then it is built upon nothing of substance. It will crumble. It has to. For its foundation is temporary, as all things called as money are. Its reality will be informationally and technologically (artfully) augmented so that it appears more virtually appealing to its volunteerest, as modernized feudal subjects, appearing falsely to be more close to the Truth of the Reality of Nature than it ever can be. And like children in want of our slightly out-of-reach and dirty pacifier, we will feed on its murky artifice. We will take the artificial teat of government as our mother, a fictional, protective, artificial womb (matrix) that is as paper thin as the money it projects to insure us. When the root of all evil is our insurance policy, our foundation, our security, then our existence can only be as the minions of a debtor’s hell.
With all of that said, the reader of this will likely call me a hypocrite in my seeking the charitable contributions of those who are reading this. I accept that. I cannot deny that I am in such a terribly unavoidable disposition that my work cannot be printed in any Real aspect so as to protect it from being just digital, erasable information. I cannot deny that I am asking for money while exclaiming the less than virtuous nature of its artifice. I am fully aware of this dichotomy, and it pains me to no end.
However, I seek no gain from this request. I seek no fame or fortune. I don’t even seek money, except to pass it from your individual hands to the book-printers hands. This money is not for me, it is for the preservation of knowledge attained by one of you, one who actually did wake up from the information war and was able to explain it for future generations so that they do not fall for such fictional, satanic designs ever again, never falling pray to the fake infowar as our own egos have. I simply wish to print my books privately without publishing them, so that they can never be claimed as government property, and thus subsequently shelved or burned at 451 fahrenheit.
To this end, I have offered the first volume of this work for free, as I have done and will do with all of my work both past and in the future. Volume II is nearing completion, and will blow this first foundational work out of the water.
In celebration of my own journey, a path and learning curve that many reading this are also on or in the middle of, I offer the following video testimony of my own path in hopes that it will help you on yours.
Here I offer a walkthrough of my activist efforts that were caught on camera or microphone. These are fond memories of pointless rhetoric done to support the information war. They are personal reminders of how enslaved we really are, pretending to have free speech while being mildly tolerated by those that grant it only to themselves. Recognizing myself not as the hero but as the slave in these seemingly victorious encounters is that change of perspective that needs to happen with each of us.
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“The American people don’t believe anything until they see it on television.”
–Richard M. Nixon, U.S. president
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To start with, here is one of my latest interviews on Leak Project. I don’t often like to use video, but here is the tip of the iceberg of my latest work. And hey, it all must be true because its on truth TV, right?
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When I first moved to the Salt Lake City area about seven years ago, after being an active member of We Are Change Los Angeles and thus leading me to a life of full-time research and activism, we formed and grew the Utah chapter of We Are Change, soon after holding a conference with Luke Rudkowski and many great (and as it turns out not so great) speakers. Live and learn…
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One of those speakers, though all other footage and recordings were lost, was Professor Steven Jones:
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And a photo opportunity at the end…
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With support, this would have been a great event. And I would love to do this again after pulling this one off logistically without flaw. But with no support, it is now only a lost memory. Again, to imagine what I could do if not constrained by money… that is perhaps the worse feeling in the world.
Note: As embarrassing as it is to ask, if anyone has any footage from this conference please link it below in the comments or send me an email. This was the first of two different conferences with We Are Change Utah where the footage was magically “disappeared.” Thanks.
As a newby in the radio circuit, and because of the nature of the strange “beehive” culture in Utah, I could not then get the support by local radio or groups, and so the attendance was very low. I paid for this conference out of my own pocket, a debt that I though would be worth it because we had recorded the event. Unfortunately, the person that volunteered to come up from Texas to recored it worked as a host for GCN, and he either purposefully or accidentally lost all the footage. He did this after we had requested Alex Jones to support and host the conference, to which he refused. And so for my debt, for my efforts, I have jack shit to show for it accept the gratefulness of those few who attended. I am, to say the least, suspicious of what happened. And to make things worse, one of my trusted WAC members stole the little money we did bring in. But on a brighter note, this got me noticed by the local radio.
As the Tea Party movement was strong then (2010), and as Sheriff Mack was one of my speakers, the BBC came to interview myself and Mack for a documentary they were creating on the Tea Party movement. While Mack ended up making a fool of himself as he fell pray to the clever interviewer, thus making it into the final documentary as what can only be called as a portrayed imbecile and fool of the “patriot movement,” they didn’t quite know what to do with me and my answers. They couldn’t pin me to any side or party. I was an anomaly.
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Needless to say, this interview didn’t make into the final cut of their twisted documentary, and BBC in no way supported our conference despite our giving it free reign to interview and film our guest speakers and make idiots of them. My conference and myself was not included or promoted. And so the BBC just used me to get an interview with some of my guests, pretending to support my efforts. Such douchebaggery.
After the conference, we arranged to have a good ol’ fashioned street action and bannering of the freeway with our 9/11 big blue banners, where we were visited by some local police that acted admirably in our support.
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Around that time we had also delivered the official dossier of evidence of 9/11 to the Attorney General of Utah Mark Shurtlif, who gleefully has been behind bars until recently as a criminal for corruption charges, along with his counterpart, former Attorney General Mark Swallow. Of course the Bar Association controls all attorneys and judges, so why would we possibly hope such protected crime would break the syndicalist stranglehold?
This was perhaps my favorite filmed confrontation, the best of in-your-face-when-you-least-expect-it guerrilla journalism, where I simply asked what the Attorney General had done with that officially received evidence, and he talked his arrogant self right into a corner. What transpired was priceless… but yet again pointless. Gotta love this one though!
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For the benefit of the less than happy Attorney General (head devilmaster), I will provide the U.S. Code here that deals with devils that do not turn evidence over to a judge…
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18 U.S. Code § 2382 – Misprision of treason
Whoever, owing allegiance to the United States and having knowledge of the commission of any treason against them, conceals and does not,as soon as may be, disclose and make known the same to the President or to some judge of the United States, or to the governor or to some judge or justice of a particular State,is guilty of misprision of treason and shall be fined under this title or imprisoned not more than seven years, or both.
Guilty or not guilty? It ain’t your choice. It’s the private brotherhood of the Bar Association’s choice, and this man is its general!!!
Deal with it, subject!
To be fair, we did also arrange a legitimate sit-down interview where the Attorney could pretend to be lawful and legitimate and on the common people’s side, being the responsible activists we were:
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But as for the “Tea Party Express,” a well-funded corporate sham, we attempted to participate and stand in unity with our supposedly celebrated “free speech” rights, while the fake Tea Party Express media heads shunned us and blocked our banners. You gotta see this to believe it. Exposing hypocrites was vastly becoming our community service and past time.
Of note here again, we see our sheriff’s officers acting with integrity and according to duty. Bravo!
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The best part as always is the media spin at the end. Never was anything we did or protested reported on accurately or in context by the mainstream news outlets.
We Are Change made national news a few times here in Utah, but this one was certainly the best, most embarrassing, and most viewed. Unfortunately, the video of my own confrontation with congressman Chafetz on the CAFR issue is lost to the ether.
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Of course, Chafetz had to rescind his comments made to us crazy conspiracy people once our little home video got loosed upon the national news.
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Whenever we got the chance, we would hand out pamphlets and DVD’s or hold up our banners to cause irrational cognitive dissonance among the residents of this “beehive” state. Like the postman, activism happens rain or shine!
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Sometimes, though rarely, it was not us doing the confronting but in fact our query calling out our own shortcomings. Here Lord Monckton agreed to sit with us after his presentation at, where else, Utah University, shedding a light on the reasons why We Are Change and other outlets of so-called “truth” were failing miserably in actually getting anything done about it in court (in government). His perspective changed my whole outlook. As a former investigative agent himself in Britain, he corrected me and changed my own course, turning my own perceptions to where the problem actually lies… the false teachings and doomed efforts of the Infowar! Here he schools me to my own embarrassment on such legal notions of the chain of custody and chain of evidence, none of which the “truth” movement ever follows, leaving our so-called “evidence” worthless and unusable, let alone undocumented and untraceable. This was my first perception into the false dichotomy of shock jocks like Alex Jones, who does triple the harm as he ever does good, causing masses of activists to act unprofessionally and not according to the law, and so that nothing we do counts as truly usable evidence.
The following is in four parts, and features me still in my own cone of ignorance trying to make a difference. I value these moments to show how much I have grown both spiritually and in reasonability. It is a reminder of how we all live under false impressions, impressions that are institutionally ingrained by both educative and entertainment-based fallacy.
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Other activist outings revealed more hard-to-stomach Realities that manifested in unlikely places. While outreaching in the airport as part of a national protest to the then new irradiated full body-scanners, we found out the hard way that free speech is a lie, is “not absolute,” and that we needed legal permits to have even limited free speech. But most of all, this was my first realization, on camera, that these guys were powerless to stop my speech unless I had one of their permits for speech. In other words, no contract, no unreasonable legal code. Permission and license is the opposite of Natural freedom, as is legal person-hood.
But what I got this head of police to say was priceless…
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A short time after that, I was handcuffed for no reason at the same airport by an over zealous police officer for attempting to say no to both the full body scanner and the body search. What transpired was a hell of a story, which I documented here:
For most of this time I had been mentoring with Walter Burien, who was teaching me about the Comprehensive Annual Financial Reporting system (CAFR) of all governments. Because I had quit my career as a sound engineer and designer to be an activist, I had the skills to help Walter make a documentary, and did so without pay. This was my first venture into documentary making, and my first time working charitably without expectation. And it felt wonderful!
Here is both the shorter trailer and the full movie:
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From this effort, and from being able to spend so much time with Walter, I became a quick study and began my own film about everything I had learned and kept self-teaching. From this came “The Corporation Nation” series of documentaries, homemade in every way by yours truly. As I look back on this project, and as is shown in the first ten minutes of the movie, I really ended up making this because when I confronted the former Comptroller General of the United States about governments massive investment portfolio, as well as the incredible land and property holdings of the United States government collectively, he outright lied to my face over and over, even claiming that government was not a corporation! This pissed me off so much that it spawned whole The Corporation Nation series, all because of liars and the lies they tell.
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In part two of The Corporation Nation I covered the pension system and its true purpose, showing government to hold mega-shares in just about all corporations around the world, the epitome of globalism having formed right under our noses. It took a four hour film to document this, with countless pictures used from the CAFR reports, showing officially that government not only owns shares in all corporations, but also votes as proxy shareholder voter for their boards of directors, for mergers and acquisitions, and other “corporate governance” issues. Talk about global empire and fascism!
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When Jan Irvin started interviewing me as more and more radio shows wanted to hear what I had to say, I made this separate film to aid Jan in exposing his own school district, and in hopes that others might follow by utilizing the same information in their own local CAFRs. Besides these movies, I wrote dozens of blog articles detailing the CAFR swindle.
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For those seeking an advanced lesson in the CAFR audit system, and to see how municipal cities, counties, and states are faking their bankruptcies, I wrote my first “book” on my blog, which I intend at some point to add to and print as well. That can be found here:
As I became more advanced in my own knowledge and comprehension of the sheer nightmarish corruption displayed in these publicly available but unknown and publicly unread CAFR reports, my local activism revealed the Sheriff of Salt Lake County (and most other county sheriffs around the nation) to be at the pinnacle of this infiltration of Agenda 21 and globalist, United Nations switchover.
Here I expose “The Sheriff Who Sold His County” by revealing the non-governmental associations and special districts that are set up to exact and extort more and more money, in our case from what was officially called a “police protection fee” charged ultimately, indirectly to the property tax, where if that fee was not then paid, the county could steal people homes and property to pay the “fee” that they swear is not actually a “tax.” Like a complicated puzzle with thousands of indistinguishable pieces, I spent months and finally figured out this scam, somehow piecing it together. Here I attempt to teach the locals what the hell just happened!
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I had several encounters with this corrupt county sheriff, the prodigal son of a Utah bloodline with seven generations of politicians that have no qualifications but their family name, a local dairy farm family that has put more than one independent farmer out of business by its political hold over this county.
Also during this time I was appearing occasionally on our local AM radio station (K-TALK 630AM), going against the grain and causing a stir in the hive mind. The sheriff that sold his county was good enough to grace us with an interview, where his true colors shown through. I wished at the time that I had actually figured out the whole scam by then, but I had not. Unwittingly though, this public spectacle by the sheriff helped me immensely to finally understand the whole scheme. He’s a slimy bastard.
Other confrontations were unfortunately not filmed, including one with the chief financial officer (CFO) of the county (note that CFO is only ever a corporate title).
Intermittent videos were made, short attempts to bring perspective to folks who knew all was wrong but couldn’t see it clearly…
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After seeing the movie “Inside Job” narrated by bloodline family member Matt Damon, who actually pretending to give a shit, I did my best to call him out to so as to publicly announce the actual truth about what happened in 2008-9 with the so-called economic crash. Naturally, he did nothing. Here I show from my films how government owned all the banks that profited, merged, and crashed through stock investment, and we see the same thing with oil companies and water companies. It is this disconnect by the public that knows not government’s stake-holding in these corporations that must be corrected, so that the complete conflict of interest of the regulators owning the companies they regulate can be comprehended. And you wonder why the shareholder (government) of oil companies doesn’t force them to clean up their spills? That would be bad for governments investment profits of course, and a corporations highest concern by law is to please and profit its shareholders!
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After years of research and comprehension, I have accumulated many articles on this blog about the CAFR reporting system. A large collection of most of those “CAFR School” blogs are linked here, along with a few radio shows about it:
It cannot be stated here with any qualification how important this system of accounting for government corporations is. It is the holy grail of open secrets. It is a game-changer. It explains in full the corruption within government and the corporate world, two realms that are literally tied at the hip, and allows us to understand lobbying for what it really is. I have spent years trying to help others comprehend its structure, which is of course not meant to be understood by the public at all. Of all the links I have provided herein, this one is perhaps the most recommended, for it is a journey into all of my research on the subject of this hidden in plain sight government accounting scheme. And its rules and best practices are currently being implemented on a global scale within all nations.
What the common citizen-ship agent does not realize is that he lives in a company store. Just as companies like the East and West India and Virginia Companies funded by the king were the true founders of the so-called colonies (plantations) of early America, we subsist today in a singular commercial company called the Untied States district and commercial jurisdiction amongst the other company stores of the United Nations. Most of us work for some publicly traded and thus government owned corporation, manufacturing or otherwise producing its commercial products, and are paid in company script (U.S. currency) that allows no competition. We then spend that currency in any one of those government-held stock corporations, from grocery stores to gas stations, and in turn pay tribute (taxation) to the main company (district) and all its several franchise subsidiaries (legal state governments and agencies). This collaboration has become so obvious at this point that banks now simply collect property tax with our mortgage (dead pledge) payments. We live, work, and play in and on the persons, places, and things (patented nouns) of government. All of our property is its property, all the territory its land. We are the employees and tenants of a feudalistic company store, renamed as a commercial nation with “liberty” for all (in an open air debtor’s prison) designed to protect the pirates and private landholders (lords) that run it.
But, as we are not educated to recognize our place and status therein, it takes someone voluntarily removed from it like me over a decade to finally see this legal matrix code for what it is. And of course, this necessarily means that I am disenfranchised from every aspect of it I can be, for to see it one must have no interest in it. One can only see one’s false, legal id-entity when one destroys his ego and stops attempting to justify his legal, artificial character and existence. And perhaps the saddest part of all this is that I would not expect those receiving a pension from this monstrous company store, whose investments are in all the corporations and associations we complain about and which are the key to government holding stock and shareholder votes in those corporations, to give up their perceived “benefits” by being wed to such a devilish partner.
Samuel Johnson, in his rather curt and unabashedly honest dictionary of 1755, defined a pension as:
PENSION – An allowance made to any one without an equivalent. In England, it is generally understood to mean pay given to a state hireling for treason to his country. (Samuel Johnson’s Dictionary of the English Language, 1755)
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But what truly is this allowance given to a group of the agents (employees and citizenships) of government that would betray their very own best interest and that of God’s Nature itself? What does government accomplish by this actuarial retirement scheme? What crimes does it get away with merely because it allows profit-sharing to its employees for foolishly allowing government to invest in the worst possible corporations throughout the world?
ALLOW – verb transitive – [Latin loco, to lay, set, place. See Lay.] 1. To grant, give or yield; as, to allow a servant his liberty; to allow a pension. 2. To admit; as, to allow the truth of a proposition; to allow a claim. 3. To admit; to own or acknowledge; as, to allow the right of the President to displace officers. 4. To approve, justify or sanction.Ye allow the deeds of your fathers. Luke 11:48. Romans 8:1. 5. To afford, or grant as a compensation; as, to allow a dollar a day for wages. 6. To abate or deduct; as, to allow a sum for tare or leakage. 7. To permit; to grant license to; as, to allow a son to be absent. (Webs1828)
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The middle and above middle class public pensioner is always the loudest to cry foul at government handouts to the poorest and most destitute of people, claiming this action of actual charity to be equal to the robbing of the taxpayer money coffers. Imagine discovering that this is pure hypocrisy, and that most of them don’t even know it themselves! For it is actually the pensioner that lives in robbery of the taxpayer coffers, in a self-deluded ignorance, as I have shown through primary evidence. Turns out that infinitely more amounts of taxpayer money go to “match” government employee “contributions” or outright pay in total for these public pension funds. It is a massive suck of taxpayer money, so much that it is hardly believable, and thus pensioners are certainly in denial of their disposition. In fact, the whole point of hiring so many redundant government employees is to specifically extract taxpayer money for each hireling by placing them into governments pension fund system. The more employees, the more exaction can be taken from taxpayer funds in all local, municipal governments. It’s just part of the global corporate investment scheme.
I explain this fully below and showed it in my documentary, The Great Pension Fund Hoax, so that no doubt can possibly remain, only cognitive dissonance. Remember, I only seek the Truth, no matter how much it hurts. And the pensioner will defend his or her “stake” in this evil cabal of the company store to the bitter end, an unwitting trainer to the rest of us. But Truth is never defeated by purposeful ignorance. Pension funds are, more than any other source, responsible for the globalism we see today. And Samuel Johnson’s definition above certainly holds true today.
We are a society that has no natural predators to fear, and so we have taken to devouring ourselves and our vital habitat to further our exponentially pointless gains in order to keep this investment and corporate governance scheme and class structure of inequality going into perpetual madness… and likely into oblivion.
Here’s a perfect example, the Sand Wars. And something everyone should see:
A look at the CAFR for any government pension fund reveals the corporate power structure that pensioners make allowance for in order to gain from that ultimate nothingness of stocks valuations and other financially void instruments of corruption. This post shows by industry just one pension fund’s investment portfolio in the industries that are otherwise continuously demonized by their bad behavior and toxic events.
Doesn’t it piss you off to know that your retirement and taxpayer money is being invested in George Bush’s Carlyle Group to the tune of multiple billions in just one government pension fund scheme?!?
Sadly, Walter Burien of CAFR1.com and I are estranged at this point, and to this fact I wish to speak here without intent of slander or attack. As I progressed in my own self-teaching, reading CAFR after CAFR after corporate AFR (annual financial report) mixed with legal code and the history of this investment system set up so long ago, my questions started becoming more of a nuisance to Walter than mere simple and actually answerable inquiries. As I contemplated more and more the reason and design behind his strategy and “Tax Retirement Fund” system, I could never find the part where his “plan” would actually fix anything or cause corporate governance of corporations to change for the benefit of us common folks as he continuously proclaimed. For once, Walter didn’t have any answers, and so my questions became mistakenly taken as personal attacks upon his “plan,” and his responses steeped more and more in resentment, as if I was attacking his intentions and not trying to help get that system going. And yet one theme of our conversations never did change, which was the self-enrichment of Walter after so much suffering as head of his own business plan. Eventually, I could not merely overlook this obvious conflict of interest, especially when Walter was no longer able to answer my questions about his designs.
I campaigned tirelessly for years on behalf of Walter, attempting to get people out there to fund his efforts, but never my own. I never asked for funding, convincing myself that it would somehow come if I kept doing the right thing; that someone would step up and back up my efforts.
Pipe dreams… or so I thought.
Suddenly and out of nowhere, Walter messaged me that he had just received a $600,000 donation (and a future pledge totaling $1 million) from exactly the kind of undeservingly wealthy trust fund baby that I figured would one day somehow wake up and consciously realize he needs to support someone like myself and Walter. But I had not campaigned anything for myself, only for Walter, trusting in his integrity. I had faith in the man, something the Bible says never to put upon any man. And now I understand those words of wisdom intimately, after so many years of broken faith in so many people.
In fact, both Walter and especially myself saw through one of those false heroes of the truth movement, Dr. Ron Paul (a signer of birth certificates). I remember when I first started calling bullshit on the whole “End The Fed” movement and the Federal Reserve mythology how I was chastised and fallaciously attacked from all sides. For to take away anyones perceived enemy causes them to start looking inwardly for the Real problems, and that would mean facing the actual, self-evident Truth. And so as soon as I understood that the CAFR of the Federal Reserve was indeed the supposedly non-existent audit of the Fed, I felt obligated in honor to share that information with my fellow “truthers.” It was this effort more than anything, including the depredation of Ron Pauls false character and hero-status, that showed me the truth about the truth movement.
After posting the first of these only primarily sourced expose’s on Ron Paul and the Federal Reserve, all I received was personal attacks. My favorite of these was on Ron Paul’s website, where the top members and managers of that (Daily Paul) site debated not on the facts presented in my blog article, but on whether or not I had enough clout and a big enough audience to cause any stink. Screw the facts, was I a threat? I couldn’t believe what I was seeing. They were only interested in keeping up appearances and holding on to the Ron Paul money-mobile and charade. And for a while it indeed was a commercial cash cow for Paul and his supporters, complete with books, T-shirts, and other worthless swag.
And big surprise! Nothing came of it.
But why did nothing come of it?
Because it was all based on foundational lies!!! And yet I was the enemy for telling the truth about the false truths about the actual Fed. I continued to find myself in this position over the years, constantly fact-checking and calling out the lies and liars that were pushing them, either willfully or unwittingly as followers putting their faith in men, but never in the actual, provable facts. Patriots for profit, we call them.
Here are my research articles explaining the true nature of Ron Paul and the Fed, and how fans and followers of these false teachers are stuck in their own paradigm.
While Ron Paul had the perfect opportunity to expose the CAFR system as the already existing and only audit of the Fed, he chose his career as a congressman instead. We challenged and challenged him to expose the CAFR to his “fans” but to no avail, proving him (and many of his supporters) to be utter fraudsters.
As far as mine and Walter Burien’s relationship is concerned, and without gory or personal detail, but as well knowing that money equals power and that power always and absolutely corrupts and leads to greed and why I try my hardest to avoid it like the plague, our story and history together ended abruptly. Walter decided that he would not use that money to fulfill all his plans that I had worked so hard to learn and promote, but to purchase land and build a large business complex upon it’s potential success in Pueblo, New Mexico. In other words, he was going to give that entire financial donation to himself in the form of equity, just like the corrupt government does in its own financial trickery. I can only assume that greed took over, as it so often does. And because I never asked for anything from Walter as payment for working on his documentary or for supporting him out of my own pocket, nothing is exactly what I got from him. I campaigned and begged without dignity for someone to support this guy, and than here was the end of it, the fruit of our efforts, and then the greedy squashing of that finally realized pipe dream. With nothing left to do business or travel with, nothing ever became of all that money to my knowledge, and it was certainly never used for the purposes I believed it would be utilized for.
Just another heartbreak in a series of heartbreaks…
That was the last I spoke to him. I stopped supporting him. I stopped asking the tough questions. And the last post I saw from him was of course Walter asking for more donations some time last year.
Again, I do not wish to belittle Walters efforts at educating or most of his works and for helping to guide my own learning curve, most of which was really from my own efforts and research. I only want to show that like so many others that have crossed my path, money is always that which destroys them or steals their good intentions. Money is always what influences one, instead of helping, to harm others. Money is always what destroys relationships and induces divorce lawyers to cause women to become greedy monsters to the men they made vows to love and cherish. It always leads to evil, to adversarial purposes. It is why I ceased my show with “Freeman Burt” every week even as he continues to harm his clients by “helping” them, and as opposing proof is inversely why Daniel stayed with me to the end of my radio show in loyalty and brotherly love and intent every week. Money corrupts all things. Only Daniel and I seemed to remained free of it, which is a testimony all by itself.
To be clear, I am asking for donations the only morally viable way I know how to do so, without that corruptive element. Nothing displeases me more than being in this disposition, for I have learned to live without such legally purchased material pleasures made in foreign child-labor sweat shops and by U.S. prison labor hidden behind adorning celebrity faces pretending to give a shit about anything but their paycheck. I seek donations only to give it to another in exchange for printing my book. I am not selling anything, and never will, for commerce is that which is diametrically opposed to Love and Charity. I merely need the only object of exchange accepted by these brainwashed business people that have the equipment to print books in a private transaction, without barcodes and artful tracking marks, signs, and symbols. I haven’t any other choice that I am aware of. I will always give this work away for free to all who ask. And those who can will or will not support me here by donating what they can. What else can I possibly do? I don’t ask for your faith in me, only in my work and the verifiable and ancient knowledge presented within. All donations will go to that purpose alone.
As for my own journey, time progressed and I kept researching and learning…
As a cancer survivor at the age of 17, I spent a large part of my life seeking the causes of cancer and understanding why only in time do we have so many childhood illnesses that are considered as “early onset” adult diseases. What I found ultimately lead me to the only plausible prime suspect: vaccines. This was my first documentary on the history of vaccines, posted in September 2011, and which in hindsight is almost sophomoric compared to what I’ve learned since then. But that is the way of everyones unique path and the journey we choose to take. We must arrive in steps, and these are my larger steps in video, documentary form:
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Early on in We Are Change we had been planning this documentary project, which I took over as the group started to become corrupt and tear apart, as so many of them do. Here is some early footage of vaccine victims we interviewed, which was not used.
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I was also asked to speak to some folks in New York City about vaccines and the documentary, which was a nice visit to my former place of residence.
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As time progressed,perhaps my greatest assembly of puzzle pieces was the Agenda 21 and Common Core plans and how they play out in globalism. Here is my lecture on the subject:
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Somewhere along the way I documented my favorite charity, the only one I know that uses 100% of donations for charity! I have worked at this center every year for 4 years here in Utah when my mom and her church visits specifically to volunteer there. It is a charity worth supporting that does wonderful work.
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My more recent public speaking engagement was in Philadelphia, where I was like a fish out of water, and it in fact caused me to expose most of the conference speakers as frauds. This didn’t go over very well, as Truth is not often what people want to hear. Imagine, freeing your mind at the Hilton! LOL!!
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I have received gifts from people along the way, from books to home-made shoes, and these are of course the most precious of all to me. One unexpected gift was this one, where a reader placed my article into video format and dubbed his own voiceover to it. I regret that I made a mistake in this article, though it was one that does not actually have anything to do with the meat of its substance. I simply made an assumption that Sanger Institute was of the ilk of Margaret Sanger, and so I wrote her in mistakenly. But this should not take away from the actual information put forward, and I am so thankful for these types of efforts by good people. These types of mistakes teach us all how easily we can make false assumptions, and as researchers must verify all things.
This is “Archons And Mind Parasites And Extremophiles, Oh My!” and I know it took this guy a lot of time to put this together. So thank you so much for your efforts! What a voice!
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Along the way, I even pretended to run for president, just to show that the common goyim people as subjects of the nation cannot be president of the nation, and to eventually expose the voting system as the fraud it is.
Though the website is history, the archive still exists. This is a very viable model that should be used. Though I don’t support Trump or his bloodline cousin Hillary, I will say that if Trump was smart he would follow this model and pick his entire staff before the election, so that people can see his “round table” of Cabinet heads and not just his silly hairdo. This is designed though as a “third party” platform. It is interesting to go back and read my individual platforms and compare them to what I know now. It is certainly healthy to view ones own ignorance recorded in the past to kill the ego of the present that will certainly reveal its own ignorance in the future…
Here is the archive for Clint 4 President, “the un-campaign:”
Finally, though the years of radio before this are not included, here are my radio archives from Republic Broadcasting and everything in between and after, which will continue to be updated with any new shows I do. An extra special thanks to my friend Drew for keeping these archives on my behalf. Again, some gifts just can’t be monetized.
5 days a week for two years I labored without pay to bring these shows to life while at the same time researching and writing my current book series. It was a hell of a ride, full of trolls and saints, with some really good interviews and a documented timeline of my own journey, much of which led to my books.
I did so many shows before this, but they are not organized in any way, floating instead randomly out in the digital wasteland of youtube videos and mp3’s.
Perhaps each of these shows, most of them two hours, are worth a penny each? That’s $5 of thanks that could be gifted towards the printing of my book. But then a Mocha Frappacino with artificial flavoring from the local Starbuck’s drive-through might be worth that $5 so as to cause a chemical reaction in your brain, so that you might forget those hundreds of hours of research and rhetoric and walk around in a frap-induced stupor. I understand… We all have our priorities.
My work has been shared and plagiarized by many outlets, including the Prison Planet/Infowars sites and others. Some offer credit, and some do not. Some use a link only without actually naming my site or name. It’s an interesting matrix we have built.
Some of my movies, with my permission and blessing, are also available not-for-profit at the dollar DVD project (http://onedollardvdproject.com) to which I see no income from, but again with my blessing and support. These include Lethal Injection, The Corporation Nation, and The Great Pension Fund Hoax.
And so here I am, at the end of this winding path through so much disinformation and psychological warfare. And of course so much happened in between when the cameras weren’t rolling.
I am well into Volume II of my book series, and will be releasing it as soon as I can get it done and edited, adding it to the current free pdf available at StrawmanStory.info. The only question I have in nervous anticipation is will I be able to print it so as to make it permanent?
That’s up to you.
If you found any value in any of my above presented works, which represent literally my life for the last 10 years plus, then I am asking you without pride to make a donation today so that I may immortalize my journey’s end, by printing my books into a solid and preservable form immune from the controllers of this internet matrix. My path from here depends on you. Again, if you wish to have a copy of the book, I am asking a gift of $30 to cover printing and shipping, leaving me enough to hopefully print Volume II without such future groveling for funding. This will be my last effort in this regard, though I will keep writing and releasing for free my books that may or may not be printed.
Thank you for all who have donated so far, going way beyond, and for all your love and support. I have one last surprise I hope to pull off, a way to realize what I have been working towards. Should be a hoot if I can get it going. You’ll know when it happens, if it happens.
Until then, any radio shows I do will be posted at the archives. My other websites are:
To the followers of this blog, thank you for reading and subscribing and for all your comments and help over the years. My future books and perhaps a documentary or two are essentially replacing and will be linked to and announced on this blog, because quite frankly, at this point soundbites and clever stories and confrontations just can’t cut through such complete and evil designs. The parts never reveal the whole, especially when the parts are never presented as a whole. Debating the finer points of so many lies and fictions just doesn’t cut it for me anymore. I seek a higher path, a higher spiritual knowledge, and I hope we may meet someday on that path.
Until then… try to keep it Real, my friends. For the greatest and only True knowledge is the distinction and purposeful consciousness of what is self-evidently Real and what is fiction. And the strangest knowledge of all is that only artificial persons, places, and things need to be proven to fictionally exist, for these are not self-evident. Understand that, and no agent of that legal matrix of word magic can touch you.
Now, let’s see… what was all that stuff worth?
If the answer is nothing, then hey, it’s my fictional person’s “birth” day on August 8th, the day my vital statistics were civilly certified and registered! How about sending me a little something to support this happy artificial creation of a legal entity day, my joyous day of nativity as an emergence into this fictional realm of legal matrix day? Send a few words to wish me a happy bondservant day, congratulating me on my pretended, legalistic corporate birth as a “natural” legal person! Send a card to me as agent for service of process at my legally registered federal address, though I don’t think Hallmark (a government owned and traded corporation) makes a greeting card for being subject under Caesar’s district, not even a sympathy card.
Anyway, at least send me your greetings and salutations, and may your own artificial life be commercially fruitful in this open-air debtor’s prison on the upper levels hell.
My main, reliable email will be:
clint@strawmanstory.info
And by the way, just so you know, it is not that we are losing our democracy to tyranny, it is that democracy only ever leads to tyranny. Tyranny is the red-headed step-child of democracy. It is the fifth and final regime of every civilization as Plato predicated. Tyranny is voted in by the democratically poisoned society. Democracy is a warning that the end is near, and should not be celebrated as a good thing. Confused? It’s a chapter of my book, which I read live on the radio, here:
Finally, I have found this last piece of wisdom to share. Seek the intent of the words of the Bible. I guarantee it is the end of all quests for Reality and Truth. To seek the Bible is not to seek religion, but instead the Natural Law. No good researcher can possibly avoid it, though they can certainly demonize it and pretend it doesn’t apply to them. But I assure you it is the cornerstone of everything. It offers the only way out of this legal hell, for it is the foundation of self-government, self-Law, not just empty religion. My books go over all this with a fine-tooth comb. The Bible teaches you only how to be your True Self again, and thus to treat all men only as their True Self, never respecting reputation, titles, names, marks, and signs. To look upon all only by its source, and all men as we were all born into Nature. The Bible, again, is not religion. Rather, it is a guide-stone on how to religiously follow the Law that is causes a sanctuary from all of man’s false legal inventions. Some people drink coffee religiously, and some watch television sitcoms religiously every week. The difference between a being a member of some corporate religion (artificial person) and actually acting religiously (verb) according to the Law of Nature (God) is the difference between darkness and light, between ignorance and knowledge, and between fiction and reality.
What law are we under? The law of mammon. For the legal law always tells us the opposite of the Bible. The Bible says to respect only men, never their persons, while the legal law respects only persons, not men. A person in law may only deal with other persons, while a man of God (of Nature) may only deal with God’s Creatures. Think about this next time your government is trying to push transgender bathrooms and gender neutral status on your person. For person is the same word as status. In the fiction of legality, we are forced to respect the status of the man’s person, which has no place or existence in Nature. There are no words, no names in Reality, and the Laws of Nature will never actually be altered, except in make-believe and under false name and title (persona).
I have found every reasonable question I may ask to be answered in scripture. It is not what you have been told.
My favorite site as a searchable, Biblical database where I can see the original words and translations is: https://www.blueletterbible.org
There are so many other posts on this blog I can hardly leave them out. But here we must come to an end.
All my love.
Good luck, and good day.
–Clint Richardson (Realitybloger.wordpress.com) –Friday, August 5th, 2016
Correction: Please note that I made an assumption I should not have without researching, one I will leave in the article as an example of how bad research and writing can sound so pleasing. While the connecting information about Margaret Sanger is certainly sound, the “Sanger Institute” I fallaciously assumed without verifying is actually not named after Margaret Sanger, but a scientist by the same name. “It was established in 1992 and named after double Nobel Laureate, Frederick Sanger.” My apologies for this mistake. All other research is vetted and verified accept this namesake connection. Genetics is proving every day to be just modern eugenics. This is a great and humbling lesson to me, as it should be a warning for you not to repeat. Always correct any mistakes if you are able. And make no assumptions in your research! –Clint
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This is a video blog. Thanks to John Lothe who recorded this research and posted it on Youtube.
Part 1 –
Part 2 –
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I seem as of late to be using the phrase “in their right mind” a lot.
For instance, I often say that nobody in their right mind should be melancholy to what is happening in the world. No one in their right mind should be ok with the fact that the U.S. government in its U.S. Code has an active biological weapons program that makes it “legal” and “acceptable” to test those biologics, radiation, vaccines, and any other thing for “research purposes” on any and every population in the world, including and especially its own. And no body politic of “people” in its right mind would sit back and allow what the United States government has become in all aspects of politics and war.
Yet the deeds are done, and the crime against us is only getting more and more organized and lethal.
And this leads me to believe that my over-use of this declaratory judgement in assumption of the default belief in the state of right-mindedness might very well be misplaced. And so perhaps it is time to consider the very strange and unbelievable reality that maybe, just maybe, the majority of the population is not in fact in their right minds. And if this is the case, well then it might just be possible that they no longer even have the ability to control their own minds…
More and more I contemplate that those who might read this blog and others like it are in fact seeking answers to questions that cannot be found with an “educated” and “entertained” mind. It is not so much that there is no answer to be found, but rather that the answers that can be found do not conform to the reasoning and intent of the asker of the questions. In other words, the questions that seem unanswerable only appear that way because their askers will not look in the places where those answers might so obviously be hiding.
The difference between history (his story) and fiction, and between science and science fiction, has been so divisively blurred and so masterfully intertwined that most of us have been educated through entertainment to ignore anything resembling reality if it has been before musingly portrayed as a story of science or other fiction. Ironically, while the science fiction of yesterday could be considered the uninhibited dream of what the future could hold, today it seems that fiction is dead, and that the rules and science of fiction have been devolved and redacted, fitting only into the defined tenets of today’s real scientific limitations. Today, fiction writers are not dreaming of future possibilities and dystopias, they are describing the planned future of a dystopian science reality. The limits now placed on the imagination of the writer of fiction seem to be solely based on the current but flexible limitations of the practice of modern science. And so the once vibrant dream of utopian philosophers has seemingly also come to its visionary death, for today’s practitioners within the institution of science have taken up not the study of nature but the art of the alteration and control of nature. Anti-nature…
And so those of us who still feel; we who still conform to and therefore know the natural aspects of empathy, logic, reason, virtue, responsibility, and all that makes up the uniqueness and wonder of man are left hopelessly wondering why everything in the world seems somehow, for lack of a better term, just innately wrong. We search for individual answers that, when thoughtfully placed in connective order, we hope might make up the clear summation of the problem at hand. And yet no matter what, the ultimate answer still seems to lay out of sensual understanding. From our sense of reality, we seek a type of knowledge that very likely cannot be obtained through the ordinary processes and facts that otherwise we may find using the traditional scientific method. For that method was created to specifically study the natural state and order of things. So we must ask ourselves some very disturbing questions:
How can we possibly use this traditional scientific method to find answers when all of nature is being corrupted by the abuse of modern scientific methods?
If science is the study of nature and how it works without the intervention of man, and if at the same time nature itself is being fundamentally altered by the false institution of science, what then should the new definition of modern science be?
More to the point, how can a reasonable researcher use traditional scientific means in logical sequence to accomplish the goals of this new non-traditional science?
What was before the study of the laws of nature is now the study of the destruction of those constants. What was before the craft of benefiting mankind through understanding the natural process is now the craft of overcoming that process to control mankind through control of nature.
So for those who seek provable answers using the traditional scientific method, it is advised that you should go back to watching re-runs of “History Channel Presents.” For today, we are going to delve into what is indeed possible yet seemingly not. And as of yet, there is no proof or test that I can offer you to satisfy your “scientific” curiosity. Instead, for a brief moment, I ask you to consider that what might be the answer to your unanswered questions may very well be so different than you expect that you won’t even wish to bring up the subject to friends and family for fear of ridicule. And honestly, the only reason I am writing this now, with the same contemplation and fear in mind, is that I have a strange feeling that only those of us left out here that are still in our right mind will believe that the following information is perhaps more self-evident than any other explanation.
The great rhetorical mind of the Scottish author and physician Sir Arthur Conan Doyle, a graduate of the University of Edinburgh Medical School no less, might be of import in this endeavor. His character Sherlock Holmes was essentially represented as the crowning authority in the use of forensic science. The word forensic comes from the Latin forēnsis, meaning “of or before the forum (court),” dating to the roman republic. Created in the late 1890’s, detective Holmes was required to use his brain, his logic and his reason to solve the case, for the modern technology of crime scene investigation was not yet in existence, and this allowed many criminals to flee justice.
Today, I ask the same of you, my dear Watson’s…
In the novels based on Sherlock Holmes; those fictional tales about the unorthodox, de-educated, non-conformative detective, it was said of man that, “His ignorance was as remarkable as his knowledge.”
Even more remarkably, the fictional detective stated that, “In solving a problem of this sort, the grand thing is to be ableto reason backward. That is a very useful accomplishment, and a very easy one, but people do not practise it much. In the everyday affairs of life it is more useful to reason forward, and so the other comes to be neglected. There are fifty who can reason synthetically for one who can reason analytically.” It is my opinion that if you are reading this blog, you may very well be one in fifty.
Of course, his most famous musing concluded that, “When you have eliminated all which is impossible, then whatever remains, however improbable, must be the truth.”
But perhaps in light of our current disposition as sentient beings searching for answers to questions that seemingly won’t be answered, it is this quote we should be romancing: “I fear that if the matter is beyond humanity it is certainly beyond me. Yet we must exhaust all natural explanations before we fall back upon such a theory as this.”
In the spirit of this Holmesian deductive reasoning, I hope that the reader will allow herein a presentation of my own theory on why everything in science and in the actions of the leaders of men seem to be centralized on creating a fictional dystopia of mis-used science rather than on the use of science to realize the dream of fictional utopia.
(Que ‘Twilight Zone’ music)
–=– Warning:
This Is Not Science Fiction! –=–
In movies, the monster is usually something that you can see. The alien from Alien. The clown from IT. The Martians from Mars Attacks. The Englishmen from Downton Abbey. And who can forget Mega Shark vs. Crocosaurus?
The use of the genre of sci-fi horror movies depicting gruesome monsters and viscously putrefying aliens has created a false dicotomy of left or right opinions regarding what the typical person might be able to believe is possible within the institutional reality of biological science, which today has seemingly crossed the barrier of perception with its primary basis now in the world of the unseen – the less-than-microscopic nano-world of genetic code. “Science” has mapped the genomes of many species, and is now hot on the trail of mapping the epigenetic on/off mechanisms of DNA/RNA encoding that controls gene expression and disease. It is one thing to see how genes are put together to make up life on earth, but an entirely more dangerous thing to have one’s hands on the knowledge and function of turning those gene’s expressions on and off. In this manner, science has become a very frightening brave new world.
The Genome project is now a thing of the past, old news, ancient technology. The Epigenome Project is now where it’s at!
The Human Epigenome Project website explains its surface goals:
The Human Epigenome Project (HEP) aims to identify, catalogue and interpretgenome-wide DNA methylation patterns of all human genes in all major tissues. Methylation is the only flexible genomic parameter that canchange genome function under exogenous influence. Hence it constitutes the main and so farmissing link between genetics, disease and the environment that is widely thought to play a decisive role in the aetiology of virtually all human pathologies. Methylation occurs naturally on cytosine bases at CpG sequences and is involved in controlling the correct expression of genes. Differentially methylated cytosines give rise to distinct patterns specific for tissue type and disease state. Such methylation variable positions (MVPs) are common epigenetic markers. Like single nucleotide polymorphisms (SNPs), they promise to significantly advance our ability to understand and diagnose human disease.
The Human Epigenome Project (HEP) is a public/private collaboration run by the members of the Human Epigenome Consortium. MVPs identified as part of the HEP will be released publicly in accordance with the HEP data release policy.
And just who or what makes up the members of this “consortium?”
Current consortium members:
The Wellcome Trust Sanger Institute is a recognised leader in genome sequencing, high-throughput systems, informatics and analysis of gene function using genetic approaches in a variety of model organisms and humans.
Epigenomics AG is a transatlantic biotechnology company with headquarters in Berlin, Germany and its wholly owned subsidiary in Seattle, Washington, USA, pioneering tomorrow’s personalized medicineby exploiting the information of DNA methylation patterns.
The Centre National de Génotypage is a national research institute set up in 1998 by the French Government in anticipation of using the genome sequencing information for the identification of genes and gene function.
Now, if you are not familiar with Margaret Sanger, you really should be. As one of the most famous soft eugenisists, her legacy includes Planned Parenthood and modern birth control. But let’s take a deeper look at this feminist de-populationist, and imagine for a moment if she had her finger on the trigger of modern genetic and epigenetic technology. Planned Parenthood would look a lot differently than it does today.
Surprisingly, even Wikipedia must admit to the truth of the easily found history of her motives (citations and sources left in):
Sanger’s 1920 book endorsed eugenics.
As part of her efforts to promote birth control, Sanger found common cause with proponents of eugenics, believing that they both sought to “assist the race toward the elimination of the unfit.”[84]Sanger was a proponent ofnegative eugenics, which aims to improve human hereditary traits through social intervention by reducing the reproduction of those who were considered unfit.[85] Sanger’s eugenic policies included an exclusionary immigration policy, free access to birth control methods and full family planning autonomy for the able-minded, and compulsory segregation or sterilization for the profoundly retarded.[86][87] In her book The Pivot of Civilization, she advocated coercion to prevent the “undeniably feeble-minded” from procreating.[88] Although Sanger supported negative eugenics, she asserted that eugenics alone was not sufficient, and that birth control was essential to achieve her goals.[89][90][91]
In contrast with eugenicist William Robinson, who advocated euthanasia for the unfit,[note 9] Sanger wrote, “we [do not] believe that the community could or should send to the lethal chamber the defective progeny resulting from irresponsible and unintelligent breeding.”[92] Similarly, Sanger denounced the aggressive and lethal Nazi eugenics program.[87] In addition, Sanger believed the responsibility for birth control should remain in the hands of able-minded individual parents rather than the state, and that self-determining motherhood was the only unshakable foundation for racial betterment.[89][93]
Sanger also supported restrictive immigration policies. In “A Plan for Peace”, a 1932 essay, she proposed a congressional department to address population problems. She also recommended that immigration exclude those “whose condition is known to be detrimental to the stamina of the race,” and that sterilization and segregation be applied to those with incurable, hereditary disabilities…[86][87][94]
Sanger’s writings echoed ideas about inferiority and loose morals of particular races that were widespread in the contemporary United States.[85] In one “What Every Girl Should Know” commentary, she references popular opinion that Aboriginal Australians were “just a step higher than the chimpanzee” with “little sexual control,” as compared to the “normal man and Woman.”[78] Elsewhere she bemoaned that traditional sexual ethics“…have in the past revealed their woeful inability to prevent the sexual and racial chaos into which the world has today drifted…”[93]
From 1939 to 1942 Sanger was an honorary delegate of the Birth Control Federation of America, which included a supervisory role—alongside Mary Lasker and Clarence Gamble—in the Negro Project, an effort to deliver birth control to poor black people.[100] Sanger wanted the Negro Project to include black ministers in leadership roles, but other supervisors did not. To emphasize the benefits of involving black community leaders, she wrote to Gamble “we do not want word to go out that we want to exterminate the Negro population and the minister is the man who can straighten out that idea if it ever occurs to any of their more rebellious members.” This quote has been cited by Angela Davis to support her claims that Sanger wanted to exterminate black people.[101] However, New York University’s Margaret Sanger Papers Project, argues that in writing that letter, “Sanger recognized that elements within the black community might mistakenly associate the Negro Project with racist sterilization campaigns in the Jim Crow South, unless clergy and other community leaders spread the word that the Project had a humanitarian aim.”[102]
One might perhaps laugh at the caption of this article,
promoting birth control while posing with her own two birthed sons.
Of course, birth control was really intended for the “lesser” races…
–=–
Ironically, but not surprisingly, Sanger’s racially pure mother Anne Higgins went through 18 pregnancies (with 11 live births) in 22 years before dying at the age of 49. Sanger was the sixth of eleven children. But then, she was apparently gifted with good blood from a good race, so that’s just alright now isn’t it?
So why should you, if indeed you are in your right mind, be concerned that the most prominent organization participating in the Genome and Epigenome Projects honor in their titles this eugenicist that promoted racial purity and depopulation? Are you frickin’ kidding me? Do you think plants, fruits, and vegetables are the only life that can be purposefully, scientifically, and genetically altered from their natural form?
Let’s get more acquainted with the institute celebrating her legacy, shall we?
Embracing a postgenomic era
The Sanger Institute will examine how genomes are implicated in the biology of disease in greater detail, with greater precision and at faster rate than previously thought possible. Genomes are rapidly becoming a part of the essential fabric of biology, rather than an expensive resource.
Our target is to understand the function of genes on a genome-wide scale. The intellectual commitment and drive of our researchers, combined with developments in technology, will allow us to make a contribution to the understanding of how genes work that is as significant as our contribution to the Human Genome Project.
This contribution will be founded in efforts to tackle the basis of common genetic and infectious disease and to build resources and tools that will help others to tackle disease. Our dual role, as researcher and resource provider, has served biology well and we believe it will become more valuable in the future.
In the next two years, we will sequence more than 1000 human genomes. By 2012, we will make stem cells in more than 10,000 genes.
Human genetics
Our research in Human Genetics will harness the power of our improving sequencing and genotyping infrastructure in order to gain a better understanding of the diversity of the human species and how this diversity influences our health and disease. By 2011, the Institute will have sequenced more than 1000 human genomes. As part of the Wellcome Trust Case Control Consortium and other similar large-scale consortia, we will continue to discover important genetic variants on the scale that is required to give insight into the genetics of common disease.
By 2013, the International Cancer Genome Consortium will have produced comprehensive catalogues of mutations in more than 50 different tumour types. This work, in which we play a leading role, will lay the foundation for clinical research to produce treatments that could help to reduce the global cancer burden.
Building on new technologies, we will help to develop a rapidly growing understanding of diseases including cancer, heart disease and diabetes. Our research outputs and resources, such as the DECIPHER database, will move into clinical practice as our biological understanding becomes clinically essential.
Infectious disease
Our capacity to analyse genomes means that we can examine the diversity of pathogens, both within and between species, on a scale unmatched within Europe. Our future research will lead to new understanding of infectious disease and its development and spread: using new technologies we can map individual organisms and the development of disease in an individual or among a population with exquisite accuracy. Embracing these technologies, our researchers will complete a staggering 10,000 pathogen sequences by 2011.
We will move rapidly to examining the interactions between pathogen and host – a vital meeting point that influences the genetics of both organisms. Our research in malaria will strengthen understanding of genetics of host-pathogen interactions. Our programmes will help to build capacity among researchers in the UK and in front-line countries facing the challenge of infectious disease. Our research into malaria shares the Global Malaria Action Plan’s morbidity reduction targets for 2010 and 2015.
Our research in pathogens will also build on the MRSA and C. difficile sequences in order to help health authorities make rational and considered plans for dealing with healthcare-associated infections.
Model organisms
Working with our collaborators, we will deliver, over the next few years, resources that will transform research using model organisms.
–=–
Cloning of genetically created mice justifies total abuse of life, for the
life is created by man and therefore owned by man. How long before
humans are treated merely as model organisms used as resources?
Oops! Too late…
–=–
These remarkable resources notwithstanding, it is our research programmes that hold increasing promise.
Our research in the mouse will give a biological understanding of the genes implicated in cancer found through other programmes, such as the International Cancer Genome Consortium. Using mouse models, we will identify and unlock the networks of genes that drive cancer.
We will develop systems to accelerate stem cell research by allowing better manipulation of cell lines and by enhancing the production of embryonic stem (ES) cells.
The resources will support new research in developmental biology, hearing and cognition.
You might say that mice are the gateway drug to human resource cloning as model organisms. For if we don’t protect that which cannot protect itself, then perhaps we deserve a similar fate.
To view this disturbing mouse resource collection, go here:
Now, those in their right mind should be very concerned with the potential of this type of power. This is like children getting ahold of God’s constructor set and becoming little creators of hell on Earth. This is not just power, but the absolute power of negative creation, undoing the natural mathematical order of the DNA of all things.
But then, no body seems to be in their right mind when considering this. For man is patenting his creation as he goes, using word magic to be the master of life itself…
(CNN) — Here’s a little-known fact: Under current law, it’s possible to hold a patent on a piece of human DNA, otherwise known as a gene.
Some breast cancers… are linked with the genes BRCA1 and BRCA2.
Companies that have acquired patents for genes have specific rights to their use, which may include diagnostic tests based on those genes, as well as future mutations that are discovered.
In a new lawsuit, the American Civil Liberties Union alleges that the policy is unconstitutional.
The targets of the lawsuit, Myriad Genetics and the University of Utah Research Foundation, hold patents to BRCA1 and BRCA2, the genes responsible for many cases of hereditary breast and ovarian cancers.
The U.S. Patent and Trademark Office is also named in the suit.
The lawsuit asserts that the patents prevent some people from accessing medical screening for BRCA1 and BRCA2. It also challenges the general patentability of genes, which has been legal since 1980. That year, in Diamond v. Chakrabarty, the Supreme Court found in favor of Ananda Mohan Chakrabarty, who used bacteria to engineer a microbe that dissolves oil. Watch Dr. Gupta explain the lawsuit »
Genes form the basic unit of heredity. With modern technology,researchers have determined that particular genes carry an associated risk of illness.
A striking 20 percent of all human genes have been patented. However, now that all 20,000 to 25,000 human genes have been mapped and sequenced through the Human Genome Project, they are in the public domain, meaning they would no longer be considered “new” for the purposes of patents, said Lee Silver, professor of molecular biology and public policy at Princeton University. Now,patents on human genes must specify a new use, such as a diagnostic test.
If a company wants to patent the purified form of an antibiotic that exists in nature in a fungus, no one challenges that, Silver said. Plant DNA,as well as human DNA,can be synthesized in a laboratory. Distinguishing this case from a patented human gene that is useful in diagnostics would require the ethical argument that the human genome is sacred — and even then, things get murky, considering that about 25 percent of human genes are shared by chimpanzees, he said.
“THE PATENT LAW SAYS NOTHING ABOUT ETHICS,” he said…
Again, it is said that power corrupts, and absolute power corrupts absolutely.
So, in reference to this notion of power, what would you consider on a scale of 1-10 the power-base of knowledge in being able to control the entire expression of the human genome within the entire population of Earth – real or synthetic? Would you say that it is a 10 on that scale perhaps if one could wipe out the expression for empathy and religious capacity? How about the expression for logical thinking and reason… would that be a corruption of power? And what about love…?
What about synthetic people, or clones? Who needs the real thing when you can hand deliver the perfect, docile, subservient beast of a patented human?
From its website, the Sanger Institute explains it’s purpose:
What we do
Our research at the Wellcome Trust Sanger Institute builds understanding of gene function in health and disease as well as creating resources of lasting value to biomedical research.
We study diseases that have an impact on health globally by investigating genomes. Building on our past achievements and based on priorities that exploit the unique expertise of our Faculty of researchers, we will lead global efforts to understand the biology of genomes.We are convinced of the importance of making this research available and accessible for all audiences…
Our research into genetics and disease
Our genomic information has a significant impact on our health. Global health problems including cancer, malaria, diabetes, obesity and infectious disease are partially determined genetically. At the Sanger Institute we are uniquely placed to build on genome sequences and to engage in biomedical research that elucidates the genetic basis of such common diseases as well as rare or neglected diseases.
Why we study genomes
Genomes are the archival instructions upon which an organism is built. The sequence data provided by the Human Genome Project is a rich source of information that drives improved understanding of human health and variation. Studying human sequences, comparing model organism genomes and investigating the effects of pathogens on humans will build knowledge of the diversity of our genomes and how this affects our susceptibility to disease…
Genomes continue to revolutionise the study of biology. Their contribution to medicine is just kicking off.
In 2011 our sequencing pipeline delivered 200,000,000,000,000 (200 trillion) bases of DNA – more than all the previous years of the Institute combined.
Coupled with the output from our genotyping pipeline, which is using the latest DNA chip technology, our researchers are able to interrogate genomes at a scale and resolution that is many orders of magnitude greater than before. This rich vein of information is enabling our researchers to discover and interpret at ever greater depth the significance of genomic variation within and between species.
Drawing on our vast genomic resources enables us to play a leading role in national and international collaborations. The techniques, databases and software we develop allow us to make vital contributions to research into the spread of infectious disease, the development of cancer, and the epidemiology of malaria, sickle cell disease and metabolic risk factors in Africa.
Our ability to answer new questions is turning received genomic understanding on its head. For example, when the Cancer Genome Project team investigated structural DNA rearrangements in the chromosomes in cancer, they uncovered an entirely new mechanism for cancer development. The team discovered that some people’s cancer genomes bore the scars of a catastrophic event that had driven them a number of steps towards cancer in a single cell cycle. The chromosomes had exploded and incorrect pasting together of the DNA had produced many cancer-driving mutations.
Another convention-busting discovery was made when our researchers sought to complete the genomic picture of the spectrum of Leishmania parasites. Seeking to understand the genomic variations responsible for the differing severity of symptoms caused by the different strains, the team made a surprising discovery. Producing high-quality reference genome sequences showed that the different strains had almost identical genetic codes, but that the strains’ genomes contained different numbers of copies of the chromosomes. This finding suggests that the parasite’s evolutionary development and success is founded on the numbers of particular genes and chromosomes it has – a genetic abnormality that would kill most organisms.
Our Pathogens teams are harnessing our high-throughput sequencing and analysis resources to compare variation between individual bacterial and viral genomes from patients to track and trace precisely the spread of disease. By comparing cholera genomes during the current global pandemic, our researchers have been able to categorically trace its origin back to the Bay of Bengal. Using the same technique, we have mapped the spread of the H1N1 flu virus across the UK during the most recent epidemic and have shown that the disease entered at a number of geographic locations at different times, before the first clinical case was identified.
Our ability to conduct genomic research at high resolution and vast scope enables us to provide the foundations for the global research community to build upon. For example, the fruits of our investment in the 1000 Genomes Project are being harvested by researchers across the globe as they use the data to enhance the resolution of the genome-wide association studies and understand the origins of genetic mutation…
Instructional genomic blueprints for cancer offered to the world?
Offering the entire mechanism for the spread of disease on the cellular level to the militaries (governments) of the world?
Sharing the origins of genetic mutation with anyone interested?
20 trillion base DNA sets deconstructed in a single year?
Perhaps my concern is not being completely burned into the readers conscious here, and perhaps that’s because the reader may not be reading this from the point of view of a racially driven, psychopathic purist de-populationist! Get it? The “Sanger” institute? In honor of dear old Margaret? This should make even the roots of your own DNA shake violently with fear and loathing. Satan, if you believe in that sort of thing, could not ask for a better tool as the defined “adversary of man,” with this toolset being the epitome of the model chemistry set to de-construct nature and reform it in man’s own image. This new world order of DNA and genomic expression belongs in no mans hands, for no man is immune from the ultimate disease of unrestrained power. There are no true ethics in the modern notion of what is “science,” because the institution of science today specifically disregards nature’s (God’s) design in order to exploit and alter the intent of that self-evident design. It studies nature only in order to change or destroy it. The diseases it is claiming to be able to treat and cure on the genetic level were of course caused by this very same institution of medical and scientific crimes against man and nature in the first place, and so the placing of our faith in such institutions to cure us from its own self-inflicted ills is fool-hearted at best. Cancer was all but non-existant before modern practices of those who profess to be professors, professionals, scientists, and doctors spread it experimentally as vaccine ingredients, rearing its ugly head according to some in history only after modern vaccination was introduced.
And that brings me to my point. We have all been stung by this beast of medical science. Vaccination is designed to apparently replace what nature has already installed within the expressions of the body as the natural immune response to outside influences. One has no allergy to bee stings, for instance, unless one is stung by the bee, which delivers its disease-causing agents through a stinging injection. Spiders penetrate by a stinging bite, as do dogs with rabies. Tetanus and hepatitis thrive many places, but can only enter the body through a stinging penetration of the skin (or through the penetration of intercourse, i.e. the exchange of bodily fluids). The vaccination needle is the simulated, weaponized sexual appendage of the science of modern medicine. We are violated by it, raped by it; we are injected (stung) with substances and DNA that would never otherwise have the capacity to enter our bodies and mix with our substance. We are literally being grafted like fruit trees with the foundational building blocks of the gene expression and DNA of other life forms, including that of our fellow man as with the injection of cloned human diploid cells (including DNA and proteins) from various aborted fetal tissues, human albumin (from blood), rhesus monkey fetal lung cells, continuous (cloned) line of monkey kidney cells, rhesus monkey fetal diploid cells, simian cancer virus-40 (and at least 79 others), vesicle fluid from calf skins, calf serum, bovine serum, bovine fetal serum, U.S. sourced bovine extract, washed sheep red blood cells (RBC’s), chick embryo, chick embryonic fluid, chicken protein, mouse serum proteins, guinea pig embryo cells, shark squalene, gelatin, hydrolized gelatin, processed gelatin, lactose, and others. These are just a few of the ingredients that you have been infected with by stingers called needles.
Vaccination is, in its most simple description, the purposeful infection of the body with foreign particles and substances. Whether those substances are good or bad, beneficial or harmful, therapeutic or deadly does not remove the fact that vaccination is nothing more than purposeful infection with disease. This is not contagion, for a vaccinated person is not necessarily contagious, though some “shedding” of the vaccine does take place after infection (vaccination). The injection of peanut oils and lactose as ingredients in vaccines, for instance, is certainly linked to localized milk and peanut allergies that are not spreadable as contagious infection to others, but are rather local reactions to otherwise harmless foods, if only they were eaten instead of injected past any natural barriers. Thus, we must think outside of the box we are placed into by media education and realize that infection is a neutral word that actually also represents any forcing of so-called “medicine” into the body.
But consider how the body then might react to monkey kidney tissue or cow blood being injected into it, bypassing the natural protective barriers for such agents through the deep, penetrating sting of the inoculation needle. It is well known that even the Rh factor of some human blood types prevents negative and positive bloods from mixing to create life. The mother’s body will literally attack the newly formed embryo of a different blood type (Rh) to kill it as a foreign infection. So imagine how incompatible your body and its blood and fluid is to cow, monkey, pig, sheep, insect, and other animal blood and protein products used in vaccines, which have no other way to enter and infect your body but through the penetrating sting of vaccination.
But let’s not stop there. For other ingredients within vaccines also have no hope of forcibly entering past your body’s defenses without the sting of a nurse or pharmacy technician with a couple of weeks of government sponsered training and indoctrination mixed with a healthy dose of cognitive dissonance. The arrogant advocate for vaccination is always one who’s livelihood depends on delivering it, no differently than those animals and insects that sting or bite in protection of their own livelihood… or to spread parasites. And the propaganda machine of fallacy and quack science fills the heads of those who subject themselves and their own children to such violations of the natural law as vaccines are.
Let’s not forget the heavy metals and other extra ingredients also used in vaccines with thinly veiled reasonings and names such as preservatives and adjuvents. Those include such other foreign particles and poisons (medicines) as formaldehyde, aluminum hydroxide, aluminum phosphate, thimerosal (mercury-based), polysorbate 80 (Tween-80), ammonium sulfate, formalin, sucrose, sorbitol, benzethonium chloride, glycerin, phenol (a compound obtained by distillation of coal tar), beta-propiolactone, 2-phenoxyethanol, polysorbate 20, yeast, chemically defined yeast-based medium, soy protein, phenol red indicator, phosphate buffered saline, monosodium L-glutamate (MSG), potassium glutamate, potassium chloride, potassium phosphate monobasic, potassium phosphate dibasic, potassium monophosphate, potassium diphosphate, sodium bicarbonate, sodium phosphate dibasic, polydimethylsiloxane (silicone), and even the known cancer causing agent aspartame.
It is therefore likely that in yours, and especially in your child’s lifetime, most or all of these listed vaccine ingredients have been injected into your body, along with the various disease causing microbes, antibiotics (anti-life), and other ingredients not listed here. And your body reacts to every one of these ingredients, either in the short or long term as the manifestation of chronic disease states. I can think of nothing else to call this but sheer insanity. The blanket acceptance of the “science” of vaccination in my mind can only be attributed to two things. Ignorance is certinaly a fine-tuned and well oiled machine within the general population. But can we really blame sheer ignorance? What about custom, routine, greed, profits, and medical advice?
But what if there is another factor at play here? What if there is another unseen force that is driving people to promote and commit to actions like vaccination, eating junk food as their main staple, taking pharmaceutical drugs that will knowingly cause more severe disease than what they will treat, and submitting themselves to the unspeakable atrocities of modern and cosmetic medicine – which is by the way the leading cause by far of death in the world, called “iatrogenic” death, or death by medicine/doctor.
Is it possible that mankind could be driven subconsciously by another infective force more powerful than ignorance, more persuasive than propaganda, and more controlling than hypnosis?
And if this possibility may indeed be the case, would man even know he was infected?
This is the theory I’d like to explore herein…
–=– The Parasite Lives By Control
And Knows No Other Path –=–
I ask you now to become a neutral.
As I postulated in the opening of this thesis, I believe that any reader of this work may have only gotten this far due to their uninfected empathy and therefore unvaccinated desire to learn the answers to questions that cannot seem to be answered by merely considering what is known or by what is normal or natural. And so the question to the answer we seek may very well sit in the world of the unseen, and may therefore be hidden in the unknown. For the purely logical thinker, who needs proof of claim to every aspect of reality, I can only try my best to qualify the facts presented herein, for I cannot show you the unseeable. I have not the tools to make proof, and so I cannot prove the unprovable. And so I ask your forgiveness in this regard, and ask that you clear your mind of what you think you know so that your limiting perceptions of reality don’t get in your own way. Yet at the same time, I wish to invoke in you your use of the logic machine, the Trivium, and to examine what I present here with the goal not of belief or disbelief, but with the desire to prove or disprove – what the scientific method once also was designed to do instead of genetically altering everything so as to create falsely created evidence of a genetically altered reality.
The question I propose to answer here to the best of my rational ability is simply this:
Can the actions and inactions for which most of mankind are exhibiting in acting against its own best interest be attributed to a parasitic infection of his brain and DNA?
First, let’s place on the exhibit table the evidence of these actions of man against his own interest.
1)Geoengineering. It is being taught in universities around the world now. It is highly regulated in the codes and statutes of government, permits are required, and international treaties are law regarding its use in war and in peacetime. It is no longer a theory, but a certified and provable current practice. In other words, it is a provable conspiracy (plan between two or more people) to significantly and purposefully alter the environment, and is a highly protected industry by governments around the world, including the United Nations. If this fact is not readily apparent to the reader, then please see the links below. For those who can see it happening in the sky above them, again I can only assume according to my presented theory here that you are not parasitically restricted from recognition and comprehension of these strange happenings. Geoengeneering though, as defined and taught in the University system, is not merely the alteration of the air and atmosphere. It is the alteration of the land and oceans as well. For more factual information on this, please see my sourced research here:
2) Species Die Offs.As we sit back and watch with a helpless feeling and a bag of Funyons, we are digitally presented with facts and figures that the surface life on planet Earth, on both the land and in the ocean, is dying. We are shown images and videos of mass schools of dead fish washed up on shores or in harbors, of hundreds of birds falling dead from the sky mid-flight, and of statistical realities of millions of species of plants, animals, and insects becoming extinct. Is it at all strange to think that this may be directly correlated with the actions of man, if as above we can see that the organized actions of man are literally altering the entire biosphere of the planet on a global scale through quite purposeful Geoengineering? Where is the logic, the empathy, and the calvary, for we cannot live without the rest of nature? That is, unless man and nature are being fundamentally altered and with genomic precision reconstituted at the cellular level to survive as hosts within such a dystopia as is apparently being created by what is seemingly, if you will, men who may very well be parasitically infected and controlled at the cellular level. And so the question may no longer be who is causing the problems, but what is infecting the brains of the men who are causing these problems?
3) Natural Healthy Foods Are Being Outlawed. “Codex Alimentarius Austriacus,” is a collection of standards and product descriptions for a wide variety of foods developed In the Austrian-Hungarian Empire between 1897 and 1911 as a voluntary effort between “experts” in the food industry and in universities. Though used in legal proceedings for identity and standards purposes, this collection is not legally enforceable. However, the bastardization of this effort was created into what is today known as the international Codex Alimentarius Commission, part of the Food and Agricultural Organization and the World Health Organization of the United Nations, which is employed as the international food codex, or “law.” This integration as a legal overlord of food took place in Austrian law in 1975. The council was created in 1958 under the joint sponsorship of the International Commission on Agricultural Industries and the International Bureau of Analytical Chemistry. And you wonder why the ingredient list on your cereal box looks like a chemistry experiment? Today, Codex Alimentarius (Latin for “Book of Food”) is a collection of internationally recognized standards, codes of practice, guidelines and other recommendations relating to what is food, production of that food, and what is considered safe as food. Food is one of those things in nature that are, well, pretty damn self-evident. And while it’s probably a good thing to know enough about nature to eat from it without being poisoned, the extent of what is now being labeled as “food” and “food ingredients” defies all possible logic… unless of course the parasitic infection of man is taken into consideration!!! Simply stated, if a parasite were hungry for the nutrient diet it needs to survive, it is logical and provable in nature that the parasite would control the actions of its host in order to cause the man or other host to “infect” itself with “food stuffs” that are in actuality harmful, poisonous, and even fatal to the man but promotive of the parasite. Inversely, it would be a logical conclusion to assume that the parasite would do anything within its power to cause the man to cease to ingest anything that might harm the parasite that would otherwise be beneficial to the man, especially those food stuffs that would kill or prevent the growth and viability of parasites. Therefore, the reasonable conclusion to be made if indeed mankind is suffering from an ancient, highly advanced, parasitic intelligence that controls man’s will would be to assume that those men who organize to write laws, alter the environment, and promote or ban certain food stuffs and ingredients would be the ones being controlled by said parasites so as to act against the best interests of man and nature while at the same time promoting the best interests of the parasite. The host only lives to serve the parasite, as far as the parasite is concerned. This is evident all throughout nature, which we will explore the evidence of in depth later in this essay. And so the answer to one of the many questions the reader may be seeking as to ascertain what the hell is happening in the world may rely on the readers ability to contemplate this theory. Why are foods being re-engineered and genetically altered? Why are they being changed in a way that provably causes such harm to man and nature while men in high authority positions pass laws to protect these genetic alterations? If these men are indeed parasitically controlled, then the answer to these questions is quite clear. And this even answers what seemed before to be the great unanswerable preponderance of all who are asking such questions… Why are they knowingly causing harm to their own environment? Don’t they have to live here too? What about their children’s future? Here again the only truly logical answer is parasitic infection. Some may call them psychopaths. But what if they simply have no capability to act in anyone’s best interest but their own, which is now only in the best interest of the parasite controlling their actions? To give a few examples of this subversion of foods that might harm the parasite, we can think back to the half century mark when propaganda was just starting to take flight. Butter, animal fats, and other staples of diets around the world were suddenly being demonized. Soon, synthetic food products like margarine, American cheese, and shortening were being advertised as replacements for fats. What the reader might not know is that cholesterol, that is to say what was demonized as “bad cholesterol,” is listed in many government sponsored research studies as being the essential ingredient in expelling pathogens from the body. No cholesterol means that disease may flourish. Other examples are Cannabis Sativa, which has properties shown to prevent and destroy diseases like cancer. We are currently experiencing the total genetic alteration of this miracle plant by companies like Monsanto seeking to genetically alter it so as to patent and control its use. The therapeutic uses, therefore, are being bred out of the plant and who knows what is being bred into it. Both marijuana and cholesterol are proven to prevent the spread of prion disease, but only in their natural form. Genetically altered stains will be useless for medical purposes, just as margarine is. Though countless examples persist, where the alteration or banning of foods, spices, seeds, and plants that are extremely healthy and more importantly can cure disease, are outrightly being replaced with synthetics, most of us in our right mind cannot even come close to creating a good reason why this is taking place against humanities best interests. And yet, here again, parasitic infection of the minds of those participating in this “food science” is in fact the only plausible answer. Not greed, not profits, and not ignorance. It seems no other plausible reason exists!
4. Unprecedented Technological Advancement. In 1946, ENIAC (Electronic Numerical Integrator and Computer) was unveiled as the supposed first true all-purpose electronic computer. Weighing in at 30 tons, the size of two semis, and consisting of 19,000 vacuum tubes, 6,000 switches, and requiring many human attendants to answer to incredible amounts of blinking lights. It had the capability in unheard of marvel to add 5,000 numbers in a single second! And it could predict through this powerful computation the trajectory of an artillery shell before it landed. Naturally it was government (military) funded! Just 20 years later, “the hand-held pocket calculator was invented at Texas Instruments, Incorporated (TI) in 1966, following their invention of the first integrated circuit in 1958, subsequently patented in 1964. In 1974, the miniature electronic calculator came into being along with the Texas Instruments’ patent for personal-sized, battery-operated calculators using a single integrated semiconductor circuit array or “one-chip” calculators. 12 years later, in 1986, calculators still represented an estimated 41% of the world’s general-purpose hardware capacity to compute information. Flashing forward only 21 years to 2007, calculators had reportedly been replaced by personal computers to the point that calculator use diminished to less than 0.05% use by 2007. And here we are today, with the 30 ounce computer replacing the 30 ton ENIAC in less than 70 years. Let’s compare that to the invention of the light bulb. In 1801, British inventor Humphry Davy invented an incandescent light bulb, and later created the “arc lamp” in 1809. Though many similar inventions were created over the years, it was not until 1880 (79 years later) that Joseph Wilson Swan became the first man with a house lit by a lightbulb at the same time Edison was plagiarizing his own patents for profit of what should be free energy. 78 years… And yet in today’s high tech world we are seeing technology double every few months or years. Many theories have been attributed to this impossible race of technological breakthroughs, including the reverse engineering of alien technology and even aliens themselves doing the work. But what if the aliens were merely parasites? What if the question is not which man is inventing things today so rapidly in succession, but instead we should be asking how is such sudden knowledge possible? Is it ancient knowledge? Is it parasitic infection that is driving the intent of men to create nuclear bombs, biological weapons, Geoengineering designs, genomic subversion and mapping, and the host of other inventions that go so far against nature and the self-interest of mankind that no other explanation makes any logical sense? In one year, 200 trillion bases of DNA catalogued… which was more than all previous years put together. Does that seem reasonable to you? Does anything our leaders and organizations or corporations are doing today seem reasonable or logical to you? Have you ever talked to anyone who is capable of inventing such super-advanced technology, or just the people who put the parts together and operate the machinery? Do they really know how it works? Could they re-create the technology that machines are programed to produce and manufacture today, or are they just worker bees for the parasite hive-mind? And let’s not forget to mention the strange advent of transhumanism, i.e. the genetic alteration of humans to interface with machines or synthetic biologic technologies.
While other examples could be looked at, perhaps it is time to explain just where I could possibly have gotten this strange notion from.
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Meet The Family: Toxoplasmosis Rules!
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This is a fascinating look into cross-species protozoan parasitic infection, which literally makes a rat act against its best interest (its own life) by making it sexually attracted to it’s most deadly enemy. It gives rewards for stupid behavior. And this parasite purposefully infects the rat just to get itself into the cat’s stomach after it eats the rat.
When toxoplasmosis infects the human brain, it also seems to create feelings of sexual reward and pleasure through dopamine production for dangerous behavior. In other words, the human is rewarded for acting against his or her best interest.
What does the government say about this?
From the CDC website we read:
Toxoplasmosis is considered to bea leading cause of death attributed to foodborne illness in the United States. More than 60 million men, women, and children in the U.S. carry the Toxoplasma parasite, but very few have symptoms because the immune system usually keeps the parasite from causing illness.
However, women newly infected with Toxoplasma during pregnancy and anyone with a compromised immune system should be aware that toxoplasmosis can have severe consequences.
Toxoplasmosis is considered one of the Neglected Parasitic Infections, a group of five parasitic diseases that have been targeted by CDC for public health action.
Keep in mind that science of vaccines and the various frequency generators in our modern conveniences specifically weakens the immune system, as do many pharmaceutical drugs.
The International Scientific Times reports:
Scientists say that the Toxoplasma gondii parasite, or Toxo for short, living in 40 percent of our brains affects our sense of fear and risk-taking. Researchers found that rats, with which humans share a number of characteristics with, infected with the Toxo parasite were attracted to the smell of cat urine, instead of being afraid of it.
“Pathways that normally responded to the smell of cat urine with alarm had been damped down, while the pleasure hormone dopamine, normally released in response to female rodent urine, was now triggered by the whiff of cat,” The Telegraph reports. Scientists say it’s all part of the parasite’s way of spreading from host to host – rats that aren’t afraid of cats are more likely to be eaten by them, thereby spreading the parasite to the cat.
In human studies, the findings were similarly alarming. While men infected with the parasite were more likely to become introverted and dress down, infected women behaved just the opposite –dressing up and acting more sociable. The more likely a person is to interact with others, the better chances the parasite has of passing itself on.
Joanne Webster, professor of parasite epidemiology at Imperial College London, told The Telegraph that parasites prefer the brain because it is removed from the body’s immune system and also because it gives them “direct access” to the mechanisms of behavior.
We’ve known about the Toxo parasite since the 1920s, when scientists learned that the parasite was present in the feces of cats. During the AIDS epidemic, before antiretroviral drugs were effective and more widely available, the Toxo parasite was blamed for the dementia that many AIDS patients experienced towards the end of their lives.
The idea that parasites could control human behavior was first investigated in the early 1990s by an evolutionary biologist at Charles University in Prague named Jaroslav Flegr.
“There is strong psychological resistance to the possibility that human behavior can be influenced by some stupid parasite,” Flegr told the The Atlantic in March 2012.
He said he first learned of the ability of parasites to control their hosts 30 years ago after reading about how a certain flatworm can control ants by taking over their nervous systems. “It was the first I learned about this kind of manipulation, so it made a big impression on me,” Flegr said.
A human brain overrun with cysts from Taenia solium, a tapeworm thatnormally inhabits the muscles of pigs.
Gee… how could a pig parasite have gotten past the blood brain barrier unless it was injected?
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“In terms of numbers, there are more parasitic infections
acquired in this country (United States) than in Africa.”
– Dr Frank Nova, NIH Parasitic Diseases Lab Chief
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A recent issue of National Geographic came with the shocking cover story named “Real Zombies: The Strange Science of the Living Dead.”
Naturally, I was intrigued. And when I read the story, my worse fears were suddenly manifest, as it revealed some of the worst possible parasite infections in nature.
Perhaps the most shocking display of the designs that can be willed by the parasite to the host is this one:
“In Costa Rica, the orb-weaving spider Leucauge argyrawill go to extravagant lengths to accommodate the needs of Hymenoepimecis argyraphaga, another freeloading wasp. The female glues its egg to the host’s body. After the larva emerges, it pokes a few holes in the spider’s abdomen and sucks its blood. When the larva has grown to full size, in a couple of weeks, the spider takes it upon itself to rip down its own web and build a new one of a radically different shape. Instead of a multistranded net designed for catching flying insects, the new web is merely a few thick cables converging at a central point. Having sucked its host dry, the larva spins its cocoon on a thread hanging from the intersection of the cables. Suspended in the air, the cocoon is nearly impossible for would-be predators to reach.”
Considering this dramatic takeover of the mind, where the spider is literally stripped of its natural instincts of survival in order to protect its unwelcome parasitic guest and thus mind-controlled to be made to demolish its own web, is it at all unreasonable to assume that this may be happening in the human population as well, which is observably and virtually doing just about the same thing?
Other documented cases include:
“A fly that infects bumblebees causes them to burrow into the ground in autumn, right before the fly emerges to form a pupa. In the ground the fly is protected not only from predators but also from the cold of winter.”
“Killifish, for example, normally stay away from the surface of the water to avoid being picked off by wading birds. But when they’re infected with flatworms known as flukes, they spend more time near the surface and sometimes roll so that their silvery bellies glint in the light. Infected killifish are far more likely to be picked off than healthy ones. And it just so happens that the gut of a bird is where the flukes need to go next to mature and reproduce.”
“Before infecting a human host, Plasmodium, the protozoan that causes malaria, spends the first stages of its life cycle in a mosquito. The mosquito needs to drink blood to survive. But this behavior poses a risk to the protozoan, because the mosquito may be crushed by the hand of an annoyed human victim, eliminating the opportunity forPlasmodium to move to the next stage of its life cycle, in the human. To reduce this risk while it is still developing in the mosquito, Plasmodium makes its host blood shy, seeking fewer victims each night and giving up faster if it can’t find a gusher of blood. Once Plasmodium has matured and is ready to enter a human host, it manipulates the mosquito’s behavior in the opposite direction. Now the mosquito grows thirsty and foolhardy, seeking out more humans each night and biting repeatedly even if it is already full. If the mosquito dies at the hand of a human, it is no longer of any consequence. Plasmodium has moved on.”
“Frederic Libersat of Ben-Gurion University and his colleagues, for example, are dissecting the sinister attacks of the jewel wasp, Ampulex compressa. The wasp stings a cockroach, transforming it into a passive zombie. The wasp can then walk its drugged victim into a burrow by the roach’s antenna, like a dog on a leash. The roach is perfectly capable of movement. It just lacks any motivation to move on its own behalf. The wasp lays an egg on the roach’s underside, and the roach simply stands there as the wasp larva emerges from the egg and digs into its abdomen. What is the secret hold that the wasp has over its victim? Libersat and his colleagues have found that the wasp delicately snakes its stinger into the roach’s brain, sensing its way to the regions that initiate movements. The wasp douses the neurons with a cocktail of neurotransmitters, which work like psychoactive drugs. Libersat’s experiments suggest that they tamp down the activity of neurons that normally respond to danger by prompting the cockroach to escape.”
“Baculoviruses, for example, infect the caterpillars of gypsy moths and a number of other species of moths and butterflies. The parasite invades its host’s cells, hijacking them to make new baculoviruses. On the outside the caterpillar appears normal, continuing to munch on leaves as before. But the food it eats is not becoming more caterpillar tissue. Instead it’s becoming more baculoviruses. When the virus is ready to leave its host, the caterpillars undergo a radical change. They become agitated, feeding without rest. And then they begin to climb. Instead of stopping in safe spots out of the way of predators, the infected caterpillars creep higher into the trees, remaining on top of leaves or on tree bark in daylight hours, when they are easily seen by predators. The baculoviruses carry genes for several enzymes. When they’re ready to leave their host, certain genes become active in caterpillar cells, producing a torrent of enzymes that dissolve the animal into goo. As the caterpillars dissolve, clumps of viruses shower down onto the leaves below, to be ingested by new caterpillar hosts. To Kelli Hoover and David Hughes of Penn State University and their colleagues, the climbing behavior of the caterpillars seemed like an exquisite example of an extended phenotype. By causing their hosts to move up in trees, the baculoviruses increased their chances of infecting a new host down below. To test Dawkins’s idea, they examined the genes in baculoviruses, to see if they could find one that controlled the climbing of caterpillars. When the researchers shut down a single gene in the virus, called egt, it continued to infect caterpillar cells and replicate as before, even turning the caterpillars to goo as before. But baculoviruses without a working copy of egt could not cause the caterpillars to climb trees. It’s unlikely that many other parasites control their hosts with a single gene; an animal’s behavior is typically influenced by a number of its own genes, each contributing a small part to the sum. So it’s probable that many parasites control their hosts with a multitude of their own genes.”
“And what of D. coccinellae and its hapless ladybug host? While at the University of Montreal, Fanny Maure and her colleagues made a startling discovery: In turning its victim into a willing bodyguard, the wasp itself may only be acting as the extended phenotype of yet another organism. The researchers found that when a wasp injects an egg into a ladybug victim, she also injects a cocktail of chemicals and other substances—including a virus that replicates in the wasp’s ovaries. Some evidence suggests it is this virus that immobilizes the ladybug, protecting the wasp’s cocoon from intruders. The virus and the wasp have the same evolutionary interests; turning a ladybug into a bodyguard produces more wasps, and more wasps beget more viruses. And so their genes work together to make the ladybug their puppet. The D. coccinellae wasp may not be the puppet master it once seemed. Instead it hides another puppet master within.”
Now you tell me that this wasps sting and payload as read above is not the exact description of the vaccination process!!! The wasp injects… a cocktail of chemicals and other substances…
And what could be a more sympathetic project for parasites that control their victims through gene expression than that of the Epigenome and Genome Projects?
Oh the joys of what can be created with genetic sequencing and vaccination of its result.
The author of this article also speculates that about 80% of ALL LIFE on Earth is in actuality parasitic in nature. 80%!
In our exploration of the horrors of parasitic brainwashing, let us not forget one of the most wonderfully bizarre and frightening parasitic manifestations of strange, anti-self-interest behavior…
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Meet the Cordyceps
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Perhaps the most intriguing aspect of the ant colony in its customary dealings with infected zombie ants due to the obvious manifestation of cordycep infection, is that the ants that are “in their right mind” forcibly quarantine the rest of the ant colony from the infected ant. And so you might want to ask yourself why we are not emulating nature in this regard? Why are we, that is we who are still collectively in our right minds, not at least quarantining ourselves and perhaps organizing to stop our own infected madmen from destroying our colony on Earth?
In 2010, National Geographic published an even more disturbing article and documentary movie on the notion of a real “zombie” infection in the human population:
“Zombie Virus” Possible via Rabies-Flu Hybrid?
Highly improbable genetic tweak could create mutant virus.
In the zombie flicks 28 Days LaterandI Am Legend, an unstoppable viral plague sweeps across humanity, transforming people into mindless monsters with cannibalistic tendencies.
Though dead humans can’t come back to life, certain viruses can induce such aggressive, zombie-like behavior, scientists say in the new National Geographic Channel documentary The Truth Behind Zombies, premiering Saturday at 10 p.m. ET/PT. (National Geographic News is part of the National Geographic Society, which part-owns the National Geographic Channel.)
For instance, rabies—a viral disease that infects the central nervous system—can drive people to be violently mad, according to Samita Andreansky, a virologist at the University of Miami’s Miller School of Medicine in Florida who also appears in the documentary.
Combine rabies with the ability of a flu virus to spread quickly through the air, and you might have the makings of a zombie apocalypse.
Rabies Virus Mutation Possible?
Unlike movie zombies, which become reanimated almost immediately after infection, the first signs a human has rabies—such as anxiety, confusion, hallucinations, and paralysis—don’t typically appear for ten days to a year, as the virus incubates inside the body.
Once rabies sets in, though, it’s fatal within a week if left untreated.
If the genetic code of the rabies virus experienced enough changes, or mutations, its incubation time could be reduced dramatically, scientists say.
Many viruses have naturally high mutation rates and constantly change as a means of evading or bypassing the defenses of their hosts.
There are various ways viral mutations can occur, for example through copying mistakes during gene replication or damage from ultraviolet light.
“If a rabies virus can mutate fast enough, it could cause infection within an hour or a few hours. That’s entirely plausible,” Andreansky said.
Airborne Rabies Would Create “Rage Virus”
But for the rabies virus to trigger a zombie pandemic like in the movies, it would also have to be much more contagious.
Humans typically catch rabies after being bitten by an infected animal, usually a dog—and the infection usually stops there.
Thanks to pet vaccinations, people rarely contract rabies in the United States today, and even fewer people die from the disease. For example, in 2008 only two cases of human rabies infection were reported to the U.S. Centers for Disease Control and Prevention.
A faster mode of transmission would be through the air, which is how the influenza virus spreads.
“All rabies has to do is go airborne, and you have the rage virus” like in 28 Days Later, Max Mogk, head of the Zombie Research Society, says in the documentary. The international nonprofit is devoted to “raising the level of zombie scholarship in the Arts and Sciences,” according to their website.
To be transmitted by air, rabies would have to “borrow” traits from another virus, such as influenza.
Different forms, or strains, of the same viruscan swap pieces of genetic code through processes called reassortment or recombination, said Elankumaran Subbiah, a virologist at Virginia Tech who was not involved in the documentary.
But unrelated viruses simply do not hybridize in nature, Subbiah told National Geographic News.
Likewise, it’s scientifically unheard of for two radically different viruses such as rabies and influenza to borrow traits, he said.
“They’re too different. They cannot share genetic information. Viruses assemble only parts that belong to them, and they don’t mix and match from different families.”
Engineered Zombie Virus Possible?
It’s theoretically possible—though extremely difficult—to create a hybrid rabies-influenza virus using modern genetic-engineering techniques, the University of Miami’s Andreansky said.
“Sure, I could imagine a scenario where you mix rabies with a flu virus to get airborne transmission, a measles virus to get personality changes, the encephalitis virus to cook your brain with fever”—and thus increase aggression even further—”and throw in the ebola virus to cause you to bleed from your guts. Combine all these things, and you’ll [get] something like a zombie virus,” she said.
“But [nature] doesn’t allow all of these things to happen at the same time. … You’d most likely get a dead virus.”
Notice that the rule spoken over and over is that “nature” will not allow this type of recombinant mixing to happen. But let’s not forget that science isn’t interested in respecting the limits of nature, but instead seeks to conquer every aspect of it. Recombination happens in the lab, and new recombinations are patented as property of these madmen. Whether this is just human curiosity or parasitic will that is creating the insanity that is the institutional destruction of all that is sacred to man and nature unfortunately cannot be answered here. But the evidence provided here I dare say supports the very possible, even probable theory that this just might be the case.
–=– The Thing Test –=–
So what in the hell can we do about this if it is a reality? After all, we can’t see them if they are indeed controlling a portion of humanity.
The real question is whether an infected human would voluntarily be able to submit him or herself to any test conceived to find out! After all, such a test would be against the best interest of the parasite, and the expression of this will to stay hidden would probably be transferred to the personality of the host.
In John Carpenter’s “The Thing,” where the stranded victims could not tell who was the parasite and who was the human, they developed a test which burned the blood samples of each subject. When the parasitic blood was burned, the reaction gave evidence of infection.
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So could such a test be used to detect those who are either infected or not infected?
Before I go all science fiction on you, I’d like to explore another avenue of control that may be explained by this parasitic infection of humanity. That is the notion of harmonic resonance and the spectrum of frequency.
One of the most tightly regulated areas in the world are the airwaves. The control and tuning of broadcast and other frequency is so governed and policed that the penalty for using the air without strict guidelines and permission from the state is harsh to say the least. I have often speculated, considering the history of Royal Rife, Tesla, and other researchers into the power of frequency to both heal and destroy life, including parasites, that the reasons for the “standards and practices” in broadcasting may very well be friendly to a parasitic infection, which would be in control of the regulators. With the advent of localized smart meters, cell phones, and other frequency radiation admiting and receiving devices that are provably dangerous to human health, I find myself ever more curious that we again knowingly act against our own best interest by ignoring the warnings and actual data.
It is a standard test, for instance, to use ultra-sound frequency in autopsy to literally activate and excite prions which in turn start mis-folding the healthy brain prions, infecting what is left of the healthy brain. This method is a specific frequency that benefits prions, and so the assumption is that there would also be an equal and opposite reaction with other specific ultra-sound ranges of frequency. Royal Rife certainly proved this to be the case with many organisms, speculating that all life had both health and death frequency ranges.
And so I musingly wonder if maybe, just maybe, it could very well be frequency that might be our Thingtest.
Perhaps the foreshadowing of this in many science fiction movies may prevent us from realizing the reality of the fiction. After all, when Mars Attacks, no body really believes this can happen:
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The alteration of the tuning of instruments is an interesting story, with the usual players. Rockafeller interests funded the United Nations in New York City, and thus within was spawned the International Standards Organization (ISO) based in London. From this organization was set the new global standard in musical tuning, from the harmonious and Biblical mathematical perfection of the healthy 432 hz to the now standard 440 hz, which is not harmonic with human health and vibration.
So why the push to directly alter what was a standard tuning for generations?
Again, I can only state here that parasitic infection is a plausible answer to all of these questions.
After all this, one thing is certain. Mere conjecture as is posited here is not going to change anything. If indeed this theory is correct, we literally would have a war on our hands to save what remains of the natural order.
–=– Archon Love –=–
One final word about this theory… It’s not really mine.
While I am providing the evidence to support it, the truth is that this notion of mind parasites dates back for many centuries and from many different sources. The gnostics warned about these archons as demented mind parasites long ago. In my understanding, even the Bible warns not to cross species and races, perhaps even for this reason of creating unnatural chimeras. And yet here we are, cannibalizing our unborn like junkie freebasers, but for therapeutic reasons of course! Again I state that no one in their right mind would allow a doctor to inject human or animal proteins and DNA into their own body, especially aborted fetal tissue. But who among us is in their right minds? Logically, is it the vaccine user and abuser, or the “clean” vaccine opponent? The answer, it seems to me, lies microscopically within the very syringe in question.
The word archon is translated from Greek to mean ruler or lord, and sometimes master. The word is used to describe past kings, law-givers, and gods. But there is a more important translation I want to bring forward here…
This is the story of the extremophile, including virtually indestructible prions. Extremophiles hate oxygen. They hate just about any environment that is healthy for human and animal life. Be it volcanos, hot springs, methane pockets, or deep freezes, the extremophile thrives in the antithesis of what we enjoy. It is important to note that with all of our meddling, the oxygen levels of the Earth are also shrinking away, again creating a more parasite friendly environment for these extremophiles while, not ironically, causing more disease susceptibility and infect-ability in humans. Just another modern global event that can certainly be explained by parasites. But nothing to see here, right?
Form the Encyclopedia Britanica we read the entry for archaea:
In some systems for classifying all of life, the archaea constitute one of three great domains of living creatures. In 1977 American microbiologist Carl Woese, on the basis of analyses of ribosomal RNA, proposed that the prokaryotes, long considered to be a single group of organisms (essentially, the bacteria), actually consist of two separate lineages. Woese called these two lineages the eubacteria and the archaebacteria. These names were subsequently changed to bacteria and archaea (the archaea being distinctly different from bacteria), but Woese’s splitting of the prokaryotes into two groups has remained, and all living organisms are now considered by many biologists to fall into one of three great domains: Archaea, Bacteria, and Eukarya. Further molecular analysis has shown that domain Archaea consists of two major subdivisions, the Crenarchaeota and the Euryarchaeota, and two minor ancient lineages, the Korarchaeota and the Nanoarchaeota.
Habitats of the archaea
Archaea are microorganisms that define the limits of life on Earth. They were originally discovered and described in extreme environments, such as hydrothermal vents and terrestrial hot springs. They were also found in a diverse range of highly saline, acidic, and anaerobic environments.
Although many of the cultured archaea are extremophiles, these organisms in their respective extreme habitats represent only a minority of the total diversity of the Archaea domain. The majority of archaea cannot be cultured within the laboratory setting, and their ubiquitous presence in global habitats has been realized through the use of culture-independent techniques. One commonly used culture-independent technique is the isolation and analysis of nucleic acids (i.e., DNA and RNA) directly from an environment, rather than the analysis of cultured samples isolated from the same environment. Culture-independent studies have shown that archaea are abundant and fulfill important ecological roles in cold and temperate ecosystems. Uncultivated organisms in the subdivision Crenarchaeota are postulated to be the most abundant ammonia-oxidizing organisms in soils and to account for a large proportion (roughly 20 percent) of the microorganisms present in the picoplankton in the world’s oceans. In the subdivision Euryarchaeota, uncultivated organisms in deep-sea marine sediments are responsible for the removal of methane, a potent greenhouse gas, via anaerobic oxidation of methane stored in these sediments. In contrast, uncultivated methanogenic (methane-producing) euryarchaea from terrestrial anaerobic environments, such as rice fields, are estimated to generate approximately 10–25 percent of global methane emissions.
The cultured representatives of the Crenarchaeota are from high-temperature environments, such as hot springs and submarine hydrothermal vents. Likewise, cultured members of the Euryarchaeota include organisms isolated from hot environments, organisms that are methanogenic, and organisms that grow vigorously in high-salt environments (halophiles). Organisms in the lineages Korarchaeota andNanoarchaeota also inhabit high-temperature environments; however, the nanoarchaea are highly unusual because they grow and divide on the surface of another archaea, Ignicoccus. Nanoarchaea, which were discovered in 2002, contain both the smallest known living cell (1/100th the size of Escherichia coli)and the smallest known genome (480 kilobases [1 kilobase = 1,000 base pairs of DNA]; for comparison, the human genome contains 3 million kilobases). Members of the Korarchaeota and Nanoarchaeota have not been detected in pure culture; rather, they have been detected only in mixed laboratory cultures.
Archaea are also found living in association with eukaryotes; for example, methanogenic archaea are present in the digestive systems of some animals, including humans. Some archaea also form symbiotic relationships with sponges; in fact, Cenarchaeum symbiosum was grown in the laboratory with its host sponge and was the first nonthermophilic Crenarchaeota to be cultured and described.
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How many times have you heard the notion that a healthy human body must be in balance between acidic and alkaline Ph levels, and that disease flourishes in an acidic environment? Well so do archons (archaea). They like methane. They like extreme environments. They like stomach acid.
But more importantly they don’t like oxygen, they don’t like ozone, and thrive in anaerobic environments. Thus one curative measure might be to flood the body with the purest of oxygen, or to commit to oxygen therapy where the blood is oxygenated outside the body and reinserted. The trend and sophist popularity of anti-oxydents is suspect as well for these reasons. You can listen to my interviews with Mr. Oxygen (Ed McCabe) here:
Archaea are ancient forms of life compared to us. They are an RNA-based life form. It is RNA that controls the DNA switches of the epigenome. And the intelligence of this kingdom and domain of life is not measurable within the limited communication structure of man. We are indeed competitive life forms.
For a basic model of the communication and control that encoded RNA expresses over DNA, and how this archaea RNA life form might intercept that communication through transcription to control the host body, here is the technical jargon:
DNA transcription is a process that involves transcribing genetic information from DNA toRNA. The transcribed DNA message, or RNA transcript, is used to produce proteins. DNA is housed within the nucleus of our cells. It controls cellular activity by coding for the production of proteins. The information in DNA is not directly converted into proteins, but must first be copied into RNA. This ensures that the information contained within the DNA does not become tainted. DNA consists of four nucliotide bases [adenine (A), guanine (G), cytosine (C), and thymine (T) ] that are paired together (A-T and C-G) to give DNA its double helical shape. Nucleotide base sequences are the genetic code or instructions for protein synthesis.
Elongation – Certain proteins called transcription factors unwind the DNA strand and allow RNA polymerase to transcribe only a single strand of DNA into a single stranded RNA polymer called messenger RNA (mRNA). The strand that serves as the template is called the antisense strand. The strand that is not transcribed is called the sense strand. Like DNA, RNA is composed of nucleotide bases. RNA however, contains the nucleotides adenine, guanine, cytosine, and uracil (U). When RNA polymerase transcribes the DNA, guanine pairs with cytosine and adenine pairs with uracil.
Termination – RNA polymerase moves along the DNA until it reaches a terminator sequence. At that point, RNA polymerase releases the mRNA polymer and detaches from the DNA.
There are three main steps to the process of DNA transcription.
RNA Polymerase Binds to DNA– DNA is transcribed by an enzyme called RNA polymerase. Specific nucleotide sequences tell RNA polymerase where to begin and where to end. RNA polymerase attaches to the DNA at a specific area called the promoter region. Since proteins are constructed in the cytoplasm of the cell, mRNA must cross the nuclear membrane to reach the cytoplasm. Once in the cytoplasm, ribosomes and another RNA molecule called transfer RNA work together to translate mRNA into a protein. This process is called translation . Proteins can be manufactured in large quantities becausea single DNA sequence can be transcribed by many RNA. Protein synthesis is accomplished through a process called translation. After DNA is transcribed into a messenger RNA (mRNA) molecule during transcription, the mRNA must be translated to produce a protein. In translation, mRNA along with transfer RNA (tRNA) and ribosomes work together to produce proteins.
Protein Synthesis: Transfer RNA – Transfer RNA plays a huge role in protein synthesis and translation. Its job is to translate the message within the nucleotide sequence of mRNA to a specific amino acid sequence.These sequences are joined together to form a protein. Transfer RNA is shaped like a clover leaf with three loops. It contains an amino acid attachment site on one end and a special section in the middle loop called the anticodon site. The anticodon recognizes a specific area on a mRNA called a codon.
Protein Synthesis: Messenger RNA Modifications – Translation occurs in the cytoplasm . After leaving the nucleus , mRNA must undergo several modifications before being translated. Sections of the mRNA that do not code for amino acids, called introns, are removed. A poly-A tail, consisting of several adenine bases, is added to one end of the mRNA, while a guanosine triphosphate cap is added to the other end. These modifications remove unneeded sections and protect the ends of the mRNA molecule. Once all modifications are complete, mRNA is ready for translation.
Protein Synthesis – Translation – Once mRNA has been modified and is ready for translation, it binds to a specific site on a ribosome . Ribosomes consist of two parts, a large subunit and a small subunit. They contain a binding site for mRNA and two binding sites for tRNA located in the large ribosomal subunit. During translation, a small ribosomal subunit attaches to a mRNA molecule. At the same time an initiator tRNA molecule recognizes and binds to a specific codon sequence on the same mRNA molecule. A large ribosomal subunit then joins the newly formed complex. The initiator tRNA resides in one binding site of the ribosome called the P site, leaving the second binding site, the A site, open. When a new tRNA molecule recognizes the next codon sequence on the mRNA, it attaches to the open A site. A peptide bond forms connecting the amino acid of the tRNA in the P site to the amino acid of the tRNA in the A binding site.
As the ribosome moves along the mRNA molecule, the tRNA in the P site is released and the tRNA in the A site is translocated to the P site. The A binding site becomes vacant again until another tRNA that recognizes the new mRNA codon takes the open position. This pattern continues as molecules of tRNA are released from the complex, new tRNA molecules attach, and the amino acid chain grows. The ribosome will translate the mRNA molecule until it reaches a termination codon on the mRNA. When this happens, the growing protein called a polypeptide chain is released from the tRNA molecule and the ribosome splits back into large and small subunits. The newly formed polypeptide chain undergoes several modifications before becoming a fully functioning protein. Proteins have a variety of functions . Some will be used in the membrane of the cell, while others will remain in the cytoplasm or be transported out of the cell. Many copies of a protein can be made from one mRNA molecule. This is because several ribosomes can translate the same mRNA molecule at the same time. These clusters of ribosomes that translate a single mRNA sequence are called polyribosomes or polysomes.
For the tech-savvy mind, we can read government sponsored research about signal transcription and communication between RNA archaea and human DNA here. It is very important to understand that this type of research is in mass and ongoing, and is very concerning when considering again our theory. Who or what is guiding these studies and for what purpose? And the real mind bending question becomes: Could man do this and other research and invention without a little help from his archaeon friends?
Determinants of transcription initiation by archaeal RNA polymerase.
Abstract
Transcription in Archaea is catalyzed by an RNA polymerase that is most similar to eukaryotic RNA polymerases both in subunit composition and in transcription initiation factor requirements. Recent studies on archaeal transcription in diverse members of this domain have contributed new details concerning the functions of promoters and transcription factors in guiding initiation by RNA polymerase, and phylogenetic arguments have allowed modeling of archaeal transcription initiation complexes by comparison with recently described models of eukaryotic and bacterial transcription initiation complexes. Important new advances in reconstitution of archaeal transcription complexes from fully recombinant components is permitting testing of hypotheses derived from and informed by these structural models, and will help bring the study of archaeal transcription to the levels of understanding currently enjoyed by bacterial and eukaryotic RNA polymerase II transcription.
Transcription factor B contacts promoter DNA near the transcription start site of the archaeal transcription initiation complex.
Abstract
Transcription initiation in all three domains of life requires the assembly of large multiprotein complexes at DNA promoters before RNA polymerase (RNAP)-catalyzed transcript synthesis. Core RNAP subunits show homology among the three domains of life, and recent structural information supports this homology. General transcription factors are required for productive transcription initiation complex formation. The archaeal general transcription factors TATA-element-binding protein (TBP), which mediates promoter recognition, and transcription factor B (TFB), which mediates recruitment of RNAP, show extensive homology to eukaryal TBP and TFIIB. Crystallographic information is becoming available for fragments of transcription initiation complexes (e.g. RNAP, TBP-TFB-DNA, TBP-TFIIB-DNA), but understanding the molecular topography of complete initiation complexes still requires biochemical and biophysical characterization of protein-protein and protein-DNA interactions. In published work, systematic site-specific protein-DNA photocrosslinking has been used to define positions of RNAP subunits and general transcription factors in bacterial and eukaryal initiation complexes. In this work, we have used systematic site-specific protein-DNA photocrosslinking to define positions of RNAP subunits and general transcription factors in an archaeal initiation complex. Employing a set of 41 derivatized DNA fragments, each having a phenyl azide photoactivable crosslinking agent incorporated at a single, defined site within positions -40 to +1 of the gdh promoter of the hyperthermophilic marine archaea, Pyrococcus furiosus (Pf), we have determined the locations of PfRNAP subunits PfTBP and PfTFB relative to promoter DNA. The resulting topographical information supports the striking homology with the eukaryal initiation complex and permits one major new conclusion, which is that PfTFB interacts with promoter DNA not only in the TATA-element region but also in the transcription-bubble region, near the transcription start site. Comparison with crystallographic information implicates the PfTFB N-terminal domain in the interaction with the transcription-bubble region. The results are discussed in relation to the known effects of substitutions in the TFB and TFIIB N-terminal domains on transcription initiation and transcription start-site selection.
In biology, the word homology as used in this study refers to the existence of shared ancestry between a pair of structures, or genes, in different species. In other words, RNA archaea can interact with DNA humans. We are compatible in a parasite-to-host kind of way. If that still isn’t clear, the archons can control us like puppets by utilizing transcription factors in the DNA transcription (communication) process of transfer RNA in protien syntheses.
This is a little bit like explaining the way a computer works in its communication by viewing the movie TRON. In the human body, this communication process of transcription that creates who we are and what our intentions will be manifested as is a bit like writing a book. The RNA must enconde the DNA and thus send various proteins throughout the body, be it for the immune response or cognitive response. These proteins are small enough to penetrate the brain.
So what is the difference between these cells, and why should we be concerned that archaeon RNA is most similar to eukaryotic RNA in regards to this transcription process?
Cells in our world come in two basic types, prokaryotic and eukaryotic. “Karyose” comes from a Greek word which means “kernel,” as in a kernel of grain. In biology, we use this word root to refer to the nucleus of a cell. “Pro” means “before,” and “eu” means “true,” or “good.” So “Prokaryotic” means “before a nucleus,” and “eukaryotic” means “possessing a true nucleus.” This is a big hint about one of the differences between these two cell types. Prokaryotic cells have no nuclei, while eukaryotic cells do have true nuclei.
Could the archaea be attributed with other qualities as well, such as king-maker? Does it explain the bloodlines and blood-types of the kings and popes being exclusively Rh-, and are the archons passed from one infected generation to to the next? Can publications like the Talmud and the Authorized King James Bible be the manifestation of this control factor? What about non-linear, 4rth generation, and other modern warfare methods, as expressed in such documents as Silent Weapons for Quiet Wars and the Iron Mountain Report? Can it explain the notion of the usurious corruption in banking, government, and religion, where vast designs of enslavement and control of the mind are institutionalized in ways that seem so incredibly convoluted and hidden that they would be impossible for man to invent? Does it explain the subversion of all that is good and nurturing in nature?
In conclusion, it seems we are in a tough position. I can only appeal to logic and reason here by providing the verifiable facts that make up the outline of this theory, and yet those traits have seemingly been hammered out of the majority of us through the very entertaining science fiction and fantasy genres that apparently reveal this reality over and over through a similitude of variations in story-telling. It’s a perfect way to hide things in plain sight if you think about it. Even the phrase conspiracy theory may be used here, though its user should be poked with a stick and examined for sanity and for brain parasites when considering that the conspiracy referred to would be responsible for the cognitive dissonance of that fallacious name-caller. I sometimes wonder if that blank stare and disconnect from reality that appears in peoples eyes when speaking to them about reality and possibility and the lines in the sky that form clouds is not some chemically induced archaeon response mechanism to keep its host in the dark about itself, like the toxoplasmosis pleasure response for stupid behavior. But I can only speculate…
And perhaps in the end that is the most frightening aspect of this whole theory. For, like the pod-people from The Body Snatchers, these seemingly psychopathic scientists, doctors, biologists, and Geoengineers would never be allowed by their parasitic infection to allow a “clean,” parasite-free person to challenge this theory in search of proof for it with funding or legitimacy for research. We would be spotted immediately; if not only for our uncontrolled, inquisitive minds in asking simply why?
If anything, this would make a fine script for a science fiction story. If only we could guess the way to a happy ending…
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–Clint Richardson (realitybloger.wordpress.com)
–Wednesday, February 4rth, 2015
Is it possible that, in our efforts to create synthetic drugs (for profit) in order to artificially mimic or replace the body’s natural health and healing processes, even while suppressing the body’s immune response to those drugs so that they may fool the natural system, we have inadvertently created a permanent state of dis-ease as the average human condition?
Let’s take an obscene example.
Over half a century ago, while researching the efficiency of the vaccine for smallpox, Japanese virologists working for the Institute For Infectious Diseases at University of Tokyo published their findings (1954) that some “viral inhibitory factor” was inhibiting the growth of their purposefully induced viral infection of laboratory research rabbits. In other words, the tiny rabbit bodies were having the natural immune response they should, which interferes with the capability of a foreign zoological pathogen to propagate (grow and reproduce) after injection. But they also discovered through isolation of this unknown and naturally occurring preventative substance that it was not originated from antibodies. The desired immunization process of antibody stimulation through vaccination was being profoundly prevented.
Three years later, at the National Institute for medical Research in London, virologists discovered similar causal effects on the growth if influenza virus in chicken egg membranes. Something was again naturally interfering with the growth of the virus after purposeful (unnatural) injection. In their research paper they coined this viral inhibitory factor as “Interferon“.
At the same time, back at the University of Tokyo, those same Japanese virologists finally discovered the essense of what they originally coined as “Viral Inhibitory Factor (VIF)”, and both research branches agreed that this anti-viral substance was caused by the same class of factors, and eventually these became officially known in medical science as “Interferon” (multiple types).
Further study revealed that these Interferon proteins reside in different human chromosomes, and a purification process of biologically active beta interferon was finally isolated in 1977. By the early 1980’s interferon protein types were isolated and cloned to show conclusive proof that indeed interferons were responsible for interfering with viral reproduction. Eventually, these interferon isolates were used as a treatment for viral infections.
So what are these naturally interfering produced factors, and why do pharmaceutical corporations hate them so much that they seek to interfere with their pre-programmed interference?
Clinically defined, Interferons (IFNs) are proteins (glycoproteins called cytokines) made and released by healthy host cells (naturally occurring cells in your body) in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They literally act as communication devices traveling as RNA messengers, allowing cells to communicate with each other like micro text messages, creating a trigger effect to “interfere” with disease and viral replication by turning on the protective defensive structure of the immune system that is responsible for activating immune cells (natural killer cells, macrophages, etc.). Interferons also increase the ability of uninfected host cells in their ability to resist new infection by virus (an invading parasite to the host cell), and communicate the known presence of tumor cells to the immune system, up-regulating antigens to T lymphocytes.
A lymphocyte is one of 3 cells from the vertebrate’s immune system found in the lymphatic system called NK (natural killer) cells, B cells, or T cells. There are currently identified 10 distinct interferons (IFN’s), 7 of which are found in humans. These are further broken down by classes (types 1, 2, and 3). All of these IFN’s are vital for the body’s defense against disease states and infections as well as prevention of tumor growth.
In layman’s terms, we could say that all of the body’s naturally healthy cells send out cell-phone calls in the form of amino acids (proteins), which float through the body as if upon a wirelessly fluid Ethernet, directly connecting to the body’s receiving phone-line like a 911 emergency call; thus literally summoning the body’s first responders in the form of the immune system to send out little firefighter cells (Natural Killer, B, and T-cell lymphocytes) to stop the spread of the fire caused by viral, bacterial, parasitic, or tumor causing pathogens that are invading the host cells.
–=– Those Pesky Little Interferons –=–
While interferons have been used in some cases as a breakthrough yet totally underutilized treatment for the slowing or halting of certain disease growth in humans, we find a much more sinister reason for such research and identification of interferons in modern medicine and vaccine production. You see, the original discovery of interferons was not an altruistic attempt to isolate and synthesize an amino acid compound that would treat disease. In fact, far from it…
Back in 1956, those Japanese and British virologists were not trying to cure disease. No, they were trying to induce disease within their animal subjects for research purposes and spread it into chicken eggs so as to grow the disease for vaccination and “other” purposes; chicken embryo substrates being the most popular method for disease culture growth. But as they learned through continuous interference from the host subjects, something kept getting in the way of their purposeful disease infection of those hosts – an at the time unknown intracellular function of the body as of yet unknown, later to be named as Interferon.
Please understand… in order to vaccinate against disease, these scientists believed that they had to stop the bodies own natural defense against the very disease these scientists were trying to purposefully infect their test subjects with. Some might call this a paradox… or just insanity. In order for their pseudo-science to supposedly work, those virologists had to figure out a way to cut the cell-phone signaling process (now known as interferon) caused by their purposeful inoculate infection of the hosts. They needed to cause the body to cease in its perfectly natural capacity to fight the very disease they were injecting into it, so as to grow the disease within that host body. This would seem to the average person to be, on the surface and rightly so, a counter-productive effort on their part. But then the average person could never comprehend what was happening behind the scenes, let alone the true purpose of funding such experimental “science” as medicine.
Let’s take the phenomenon known as Auto-Immune Deficiency Syndrome (AIDS) for example…
What are its symptoms?
Rare cancerous tumors, viral-like infection, wasting syndrome, and general immune-supression of the lymphatic system.
Sound familiar? Like maybe the body’s phone-lines are down?
The body works though a system of communication devices in bilogical form. When one part or system of the body needs to communicate with another, it does so through a highly advanced structure of expressive signaling and transduction; the release of various types of cells, proteins, and other substances that trigger each inter-dependent system to respond in kind. It is this body-wide platform of cellular communication that is being attacked and blocked by the introduction of inhibiting factors like infectious prions and other melevolent substances.
The body works just fine until it is stung and thus injected (vaccinated) with foreign proteins, DNA, RNA, and other ingreedients that in no other way would ever be able to insert themselves into the body of man (or rabbit).
The main issue with AIDS patients is the lack of the body’s immune response regarding the production of T Lymphocytes, commonly called T-cells. For some reason, despite the body’s many dis-ease states as symptoms of the AID-syndrome, the body just isn’t getting the hint to produce the very thing that it needs to fight infection. It seems we have a failure to communicate here… For some reason the emergency 911 cell-phone lines seem to be cut, and the first responders (T-cells) are just not being called into action by the healthy cells that are under attack. Their chemical screams for help are going unheard. It’s as if the immune system labor union went on strike, and these “AIDS” symptoms are the resulting chaos and unrest that ensues throughout the body.
Not ironically, these are the same symptoms of what is known as Gulf War Syndrome, a known vaccine induced disease state thought by many researchers to be caused by vaccine adjuvants like squalene and other ingredients injected into the guinea pig soldiers of our military.
But what could possibly cause such a chain reaction throughout the body’s immune-supressive system?
What could possibly have been introduced within the body to prevent its ability to make a protein phone call, just like in those poor test-rabbits so many decades ago?
What is preventing interferon from interfering with the disease process, defeating its attempts to transmit its signal for help to the imune system?
Enter bioengineering and the novel prion…
So how could this novel disease state be simultaniusly spread
throughout Africa and eventually the first world?
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–=– Altering Gene Expression: Just A Little Pinprick –=–
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“The genetic code is universal…. The complete word-for-word universality of the genetic dictionary is, for the taxonomist, too much of a good thing.”
–Evolutionist Richard Dawkins, in his book, ‘The Blind Watchmaker’ (1986, p. 270)
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“It is recognized by molecular biologists that the genetic code is universal, irrespective of how different living things are in their external appearances.”
–Creationist Robert Kautz, in his book,
‘The Origin of Living Things’ (1988, p. 44)
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“The construction and metabolism of a cell are thus dependent upon its internal ‘handwriting’ in the genetic code. Everything, even life itself, is regulated from a biological viewpoint by the information contained in this genetic code. All syntheses are directed by this information.”
–A.E. Wilder-Smith, United Nations scientist (1976, p. 254).
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“It may seem a platitude to say that the offspring of buttercups, sparrows and human beings are buttercups, sparrows and human beings… What then keeps them, and indeed living things in general, “on the right lines?” Why are there not pairs of sparrows, for instance, that beget robins, or some other species of bird: why indeed birds at all? Something must be handed on from parent to offspring which ensures conformity, not complete but in a high degree, and prevents such extreme departures. What is it, how does it work, what rules does it obey and why does it apparently allow only limited variation? Genetics is the science that endeavours to answer these questions, and much else besides. It is the study of organic inheritance and variation, if we must use more formal language.”
–British geneticist, E.B. Ford, ‘Understanding Genetics’ (1979, p. 13).
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“Tablets of stone prepared by the Babylonians some 6,000 years ago have been interpreted as showing pedigrees of several successive generations of horses, thus suggesting a conscious effort toward improvement. Other stone carvings of the same period illustrate artificial cross-pollination of the date palm as practiced by the early Babylonians. The early Chinese, many years before the Christian era, improved varieties of rice. Maize was cultivated and improved in the western hemisphere by the American Indians, beginning at an early period in their history. In another era, Hippocrates, Aristotle, and other Greek philosophers made observations and speculations suggesting genetic principles.”
–Eldon Gardner, ‘The History of Biology’ (1972, pp. 399-400)
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“And God said, let the earth put forth grass, the herb
yielding seed, and the fruit tree yielding fruit after its kind,
wherein is the seed thereof upon the earth, and it was so.
And the earth brought forth grass, the herb yielding seed and
the fruit tree yielding fruit after its kind whose seed was in itself.”
–The Bible, Genesis 1:11-12
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“In the first chapter of Genesis, however, because it is a matter of the greatest religious importance, the Bible speaks clearly and finally on a matter of biology. After its kind is the statement of a biological principle that no human observation has ever known to fail. The most ancient human records engraved on stone or painted on the walls of caves bear witness to the fact that horses have ever been horses, bears have ever been bears, geese have ever been geese, reindeer have ever been reindeer. The most desperate and subtle efforts of man in modern times have been unable to alter this divine decree. The Bible teaches that from the beginning there have been a large number of types of living things, man included, which were so created as to remain true to their particular type throughout all generations…. The latest results of modern biological research, Mendel’s Laws, agree exactly with what was written by Moses three thousand years ago—and they also elucidate it…”
Byron Nelson, ‘After Its Kind’, (1967, pp. 3,103)
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“…once a fertilized, (a) single human cell begins to develop, the original plans are faithfully copied each time the cell divides (a process called mitosis) so that every one of the thousand million million cells in my body, and in yours, contains a perfect replica of the original plans for the whole body”.
–Evolutionist John Gribbin (1981, p. 193)
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“The Nobel laureate, F.H. Crick has said that if one were to
translate the coded information on one human cell into book form,
one would require one thousand volumes each of five hundred pages to do so.
And yet the mechanism of a cell can copy faithfully at cell division
all this information of one thousand volumes each of
five hundred pages in just twenty minutes.”
–Dr. Wilder-Smith (1976, p. 258).
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“Every organism has in it a store of what is called genetic information… I will refer to an organism’s genetic information store as its Library…. Where is the Library in such a multicellular organism? The answer is everywhere. With a few exceptions every cell in a multicellular organism has a complete set of all the books in the Library. As such an organism grows its cells multiply and in the process the complete central Library gets copied again and again…. The human Library has 46 of these cord-like books in it. They are called chromosomes. They are not all of the same size, but an average one has the equivalent of about 20,000 pages…. Man’s Library, for example, consists of a set of construction and service manuals that run to the equivalent of about a million book-pages together.”
“It is an indication of the sheer complexity of E. coli
that its Library runs to a thousand page-equivalent”
–A.G. Cairns-Smith (1985, pp. 9,10,11)
“The DNA in living cells contains coded information. It is not surprising that so many of the terms used in describing DNA and its functions are language terms. We speak of the genetic code. DNA is transcribed into RNA. RNA is translated into protein. Protein, in a sense, is coded in a foreign language from DNA. RNA could be said to be a dialect of DNA. Such designations are not simply convenient or just anthropomorphisms. They accurately describe the situation.”
–Lester and Bohlin (1984, pp. 85-86)
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Further, consider that human beings have learned to store information on clay tablets, stone, papyrus, paper, film, cassettes, microchips, etc. Yet ‘human technology has not yet advanced to the point of storing information chemically as it is in the DNA molecule‘
“It is not possible for a code, of any kind, to arise by chance or accident. The laws of chance or probability have been worked out by mathematics… A code is the work of an intelligent mind. Even the cleverest dog or chimpanzee could not work out a code of any kind. It is obvious then that chance cannot do it… This could no more have been the work of chance or accident than could the “Moonlight Sonata” be played by mice running up and down the keyboard of my piano! Codes do not arise from chaos”
–Professor Andrews (1978, pp. 28,29).
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–=– Prions:
Infecting The World
Through Vaccination –=–
So what happens when man comes clumsily and irresponsibly into the age of molecular science, where he begins to intermix species through inoculation? How can man know if his limits truly are what is written in the ancient scriptures and philosophies of moral men unless he seeks the answers by destroying the perfection of nature’s mathematical equations of the biology of life? How can we know the limits of genetically altered life if we don’t push those limits to the very brink of extinction of species, including our own?
Ancient warnings are for pussies!!!
In my previous research, I have postulated the horrifyingly evidence-based theory that all modern disease states, from the dementia’s to cancer to AIDS, have been induced through the vaccination process via the direct bodily injection of foreign “infectious” proteins called prions. Further research has all but confirmed the reality of this notion, showing that the inherent protective foundation of these cellular proteins in cell health (before infection) are essential to life itself.
Prion protein aids bone marrow
New study findings point to possible stem cell role for normal form of protein
By Charles Choi | January 31, 2006
The normal form of prion protein (PrP) appears necessary for bone marrow stem cells to renew themselves, scientists reported online this week in the Proceedings of the National Academy of Sciences. These findings suggest a potential physiological function in stem cells for the normal form of the widely expressed protein. “Prior to this work there was no hint that PrP had a function in stem cell biology,” co-author Andrew Steele at the Whitehead Institute for Biomedical Research in Cambridge, Mass., told The Scientist. “We are now looking into PrP function in other adult stem cells, particularly neural stem cells.” Prions are infamous for being associated with transmissible spongiform encephalopathies (TSEs) such as mad cow disease, but the function of PrP — the normal, widespread and highly conserved form of prions — remains a mystery. In preliminary studies, co-author Cheng Cheng Zhang discovered 40% of adult mouse bone marrow cells expressed PrP on their surfaces. More than 80% of these PrP-marked cells werered blood cells or their developmental precursors, suggesting PrP might be a marker for long-term hematopoietic stem cells, which can give rise to the entire adult blood system. To determine if PrP was a marker for long-term hematopoietic stem cells, the researchers took bone marrow cells from wild-type mice and purified them into fractions, some of which expressed PrP. Six months after transplantation into lethally irradiated mice, the researchers saw both short- and long-term engraftment in mice that received PrP-containing cells, but only short-term engraftment activity in mice receiving non-PrP cells. While PrP is a marker for long-term hematopoietic stem cells in wild-type mice, PrP-knockout mice still possess these cells, as well as relatively normal levels of their derived progeny. To determine what function PrP might normally have in hematopoietic stem cells, the researchers carried out several rounds of bone marrow implantations. First they transplanted bone marrow from either wild-type mice or a PrP-null strain into lethally irradiated mice. When the engrafted marrow flourished and generated peripheral blood cells, the researchers implanted the newly reconstituted bone marrow into another lethally irradiated mouse group, then repeated the process a third time. In each round after the first, bone marrow originating from PrP-null mice experienced a dramatically reduced ability to renew itself,while cells from the wild-type mice did not. Retroviral infections that expressed PrP in recipients of PrP-null bone marrow rescued this defective process, suggesting PrP is necessary for hematopoietic stem cell self-renewal. Odile Kellerman at the Pasteur Institute in Paris, who did not participate in this study, noted prions often trigger neuron death in TSEs after long incubation periods,” similarly, PrP only impacted hematopoietic stem cells over the long term. “In both cases, PrP appears to contribute to the long-lasting adaptation of cells to injury,” she told The Scientist. Kellerman suggested that when PrP function is disrupted, cells try to adapt, “but in the long term, this turns out to be detrimental.” The exact mechanism behind how PrP might contribute to hematopoietic stem cell renewal remains unknown. Co-author Harvey Lodish speculated PrP might bond to and concentrate a hormone on the cell surface, or help stem cells adhere to neighboring cells or extracellular matrix. “It should prove fairly straightforward to see if it is adhering to other proteins or any known or unknown hormones,” he told The Scientist. William Stanford at the University of Toronto, who did not participate in this study, noted that PrP is tethered to cell membranes via a glycosylphosphatidylinositol (GPI) anchor, similar to hematopoietic stem cell marker Sca-1. “This suggests these GPI-anchored proteins, which have similar functions, may operate through a common mechanism,” Stanford told The Scientist. Future experiments could investigate whether overexpressing PrP in hematopoietic stem cells increases self-renewal, and rescues self-renewal defects such as in the Sca-1 deficient mouse, Stanford added — or if genetically substituting PrP with a different GPI-anchored protein rescues the self-renewal defect seen in PrP-null mice. cqchoi@nasw.org Links within this article C.C. Zhang et al. “Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal.” PNAS Early Edition.
Neurons and Astrocytes Respond to Prion Infection by Inducing Microglia Recruitment
Abstract
The accumulation and activation of microglial cells at sites of amyloid prion deposits or plaques have been documented extensively. Here, we investigate the in vivorecruitment of microglial cells soon after intraocular injection of scrapie-infected cell homogenate (hgtsc+) using immunohistochemistry on retinal sections. A population of CD11b/CD45-positive microglia was specifically detected within the ganglion and internal plexiform retinal cell layers by 2 d after intravitreal injection of hgtsc+. Whereas no chemotactism properties were ascribed to hgtsc+ alone, a massive migration of microglial cells was observed by incubating primary cultured neurons and astrocytes with hgtsc+ in a time- and concentration-dependent manner. hgtsc+ triggered the recruitment of microglial cells by interacting with both neurons and astrocytes by upregulation of the expression levels of a broad spectrum of neuronal and glial chemokines. We show that, in vitro and in vivo, the microglia migration is at least partly under the control of chemokine receptor-5 (CCR-5) activation, because highly specific CCR-5 antagonist TAK-779 significantly reduced the migration rate of microglia. Activated microglia recruited in the vicinity of prion may, in turn, cause neuronal cell damage by inducing apoptosis. These findings provide insight into the understanding of the cell-cell communication that takes place during the development of prion diseases.
In vitro infectivity study in Cell stirs tempest in a test tube
By Brendan Maher (bmaher@the-scientist.com) | April 21, 2005
Protein aggregates generated in a test tube infected wildtype hamsters with a disease much like scrapie, according to an article appearing this week in Cell. Such a demonstration has, in the past, been called the gold standard of proof for the prion hypothesis, Stanley Prusiner’s Nobel-winning assertion that infectious, self-replicating protein isoforms are the culprit in transmissible spongiform encephalopathies (TSEs) like scrapie, Creutzfeldt-Jakob disease, and mad cow disease.
Study coauthor Claudio Soto, said that this demonstration, together with a paper published by Prusiner’s group last summer, should allay most doubts. “There is really little room for skepticism,” he told The Scientist.
But the study has done little to quiet prion hypothesis skeptics. “I’m not going to abandon alternative hypotheses for the time being,” said Robert A. Somerville of the Institute for Animal Health, Edinburgh.
While Prusiner’s group had successfully infected a mouse with a recombinant protein derived from bacteria, some argued that their use of transgenic mice susceptible to the disease undercut the power of the demonstration. In the new study, researchers at the University of Texas Medical Branch, Galveston, Universidad Autonoma, Madrid, and the University of Chile in Santiago fine-tuned a cyclical process for amplifying aggregated protein from an infected hamster brain. Through serial dilutions, they were able to infect a wildtype hamster with in vitro–produced aggregates without any traces of the original infectious brain. But skeptics, including a member of Prusiner’s group, argue that using material from a diseased hamster brain could have resulted in residual contamination.
Soto’s group has been using a process that they call protein misfolding cyclic amplification (PMCA), which aids the aggregation of the normal cellular protein PrPc into the misfolded, polymer-forming PrPres that is associated with TSE pathology. The process works in a fashion similar to polymerase chain reaction (PCR) amplification of oligonucleotides. After seeding PrPc with PrPres, the solution is incubated and sonicated. “Once the aggregates become long enough, we split them into smaller pieces so that in a new conversion, a new incubation, they are able to convert more and more of the normal protein,” Soto explained.
Crucially, however, the PrPres “seed” comes from infected hamster brain homogenate, while the normal PrPc comes from healthy hamster brain homogenate. “They actually started from infectious material, and we didn’t,” said Giuseppe Legname, of the University of California, San Francisco, and co-author on the Prusiner paper. “It’s an alternative approach to demonstrate thatyou might make prions, but to say that these are synthetic prions, it’s very difficult.”
Soto insisted that serial dilutions between rounds of PMCA reduce scrapie brain homogenate to an amount equivalent to a 10 to the minus 10th and a 10 to the minus 20th–fold dilution. Infectivity generally drops off after 10 to the minus 9th, according to the paper. “We’ve completely ruled out the possibility that the infectivity is still remaining from… the original brain,” Soto said...
While the article continues to criticize the control group results, which you may read at the link above, the important point here is that scientists are creating prions and making them purposefully more infectious. They are testing them in various substances and frequencies. And through the ultra-sound sonic vibration described above as protein misfolding cyclic amplification (PMCA), they are able to excite the growth factor of infectious prions so that they take over (mis-fold) healthy brain tissue much quicker. This PMCA process is used in autopsy to detect prion disease.
I have my own concerns that these ultra-sound frequencies are the same as used in cell-phone towers and in the process of ultra sound for unborn infants and other medical procedures, as well as other frequencies unknown via smart meters, radio waves, etc. We are playing with the fuel for the fire and there is virtually no escaping this permanent state of sonic bombardment…
It is also interesting to note that two men wsere cured of AIDS symptoms by receiving a bone marrow transfusion not so long ago…
(CBS News) Two men who’ve had HIV for years may now be free of the disease following bone marrow transplants, researchers at Brigham and Women’s Hospital in Boston announced Thursday.
The new research has some attendees at the XIX International AIDS Conference in Washington, D.C. hopeful for a cure.
Both patients were being treated for cases of cancer. One of the patients underwent a bone marrow transplant two years ago at the Dana-Farber/Brigham and Women’s Cancer Center in Boston, the other had the procedure done four years ago at the same hospital. NBCNews.com reports that one of the patients is in his 50s and has been infected since the early 1980s towards the beginning of the AIDS epidemic and the other man, in his 20s, was infected at birth.
Both stayed on their antiretroviral medication regimens, the standard treatment of HIV, following the transplants.
The researchers discovered that overtime as the patients’ cells were replaced by cells from the donor, evidence of HIV in the patients’ blood tests disappeared. The researchers also said both patients have no signs of HIV in their DNA or RNA and levels of their disease-fighting antibodies have also decreased. The researchers think the medications helped allow these cells to be replaced.
“This gives us some important information,” one of the researchers Dr. Daniel Kuritzkes, an infectious disease specialist at the hospital and Harvard Medical school said in a press release. “It suggests that under the cover of antiretroviral therapy, the cells that repopulated the patient’s immune system appear to be protected from becoming re-infected with HIV.”
The researchers themselves won’t call it a cure yet, saying they still need to check more tissues for traces of the disease. But they were surprised to see no signs of HIV beyond what’s seen in a blood test.
“We expected HIV to vanish from the patients’ plasma,but it is surprising that we can’t find any traces of HIV in their cells,” said co-resarcher Dr. Timothy Henrich, also of BWH and Harvard. “The next step is to determine if there are any traces of HIV in their tissue.”
The researchers’ announcement comes days after Timothy Ray Brown, the man known as the “Berlin Patient,” held a press conference in Washington, D.C., to say he’s still cured of AIDS five years after undergoing a bone marrow blood transplant…
It is important to note that the chemokine receptor-5 (CCR-5) antagonist prevents the cellular binding of the HIV-1 virus, as is explained in this video:
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And how do these prions effect disease states?
Let’s take for example Multiple Sclerosis:
“The etiology of Multiple Sclerosis (MS) is unknown. Existing epidemiologic data suggests that MS can be an infectious disease. MS used to be classified as one of the ‘slow infections‘–many of these are caused byprions. Prions are small, proteinaceous, infectious particles–distinguished from viruses by the absence of intrinsic nucleic acids. In a contrast to the ‘classic’ prional diseases (Kuru, Scrapie or Creutzfeldt-Jacob Disease) that in CNS affect primarily neurons, the ‘target’ cell in MS is an oligodendrocyte. This may explain differences in disease presentation. This paper presents a pathophysiological model of MS based on the assumption that MS is a prional disease. Processes leading to the demyelination in Multiple Sclerosis seem also to involve lymphocytes, astrocytes and macrophages as well as the interferon system…”
NOTE: The protein that prions are made of (PrP) is found throughout the body, even in healthy people and animals, and necessarily protects cells from infections. However, PrP found in infectious material has a different structure and is resistant to proteases, the enzymes (proteins) in the body that can normally break down other proteins. The normal form of the protein is called PrPC, while the infectious form is called PrPSc — the C refers to healthy ‘cellular‘ PrP, while the Sc refers to infectious ‘scrapie‘, the prototypic prion disease, occurring in sheep. The infectious isoform of PrP, known as PrPSc, is able to convert normal PrPC proteins in humans into this infectious isoform by changing their conformation, or shape. This, in turn, alters the way the proteins interconnect, creating symptoms like transmissible spongiform encephalopathy (holes in the human brain like mad cow disease). PrPSc always causes prion disease. In the end, no cellphone call can be made if the interferon protein is infected and mis-folded before it is able to reach its receiving protien that would activate T-Cells or other immune responses. Another word for mis-fold might be easier to understand as to misinform. The immune system is being lied to in a strange, chemically unbalanced way due to prion protein infections (mis-folding). Sheep blood (serum) is a popular vaccine substrate to grow vaccines for humans upon, and the protein and DNA cannot be filtered out of the final vaccine product. There are no other viable explanations why infectious prions from animals would intermingle within a human body (xenotransplantaion/xenografting).
This interference that infectious prions cause to interferon and other protein-based signaling and transcription cells is shown in the research studies below. For those with the gumption, let’s play a biological game of connect the dots.
Continued…
RESULTS
Prion infection is accelerated in (interferon type 3) IRF3-deficient mice…
The IRF3-dependent pathway is protective against prion infection in cell culture.
We tested whether over-expression of IRF3 (interferon) could affect the production of PrPSc (infectious/mis-folded prions) in the cell culture models. The level of PrPC (healthy prions) was not affected by the transient expression of the genes in uninfected N2a58 cells (data not shown). PrPSc was significantly decreased by overexpression of IRF3 in the 22L-N2a58 cells (Fig. 5A). We confirmed that the activated form of IRF3 (phosphorylated at Ser396 of IRF3) increases in a dose-dependent manner after transfection of the IRF3 gene in both 22L-N2a58 cells (Fig. 5A) and uninfected N2a58 cells (data not shown), indicating that the upregulation of IRF3 phosphorylation seen in the Fig. 5A is most likely due to an increase in the level of IRF3 protein after transfection.
To investigate the effect of downregulation of IRF3 in the 22L-N2a58 cells, we performed knockdown experiments using small interferingRNAs (siRNAs). IRF3 expression was significantly decreased by two types of siRNAs against IRF3, whereas β-actin expression, as the internal standard, was not changed (Fig. 5B)… These data suggest that IRF3 has an inhibitory effect on the production of PrPSc in the 22L-N2a58 cells.
To further evaluate the protective effect of IRF3… After incubation with 22L-infected BH (22L-BH), the cell clones were subcultured for five passages and analyzed by Western blotting with anti-PrP antibodies. The values of the PrPSc/PrPC ratio were inversely correlated with the values of the IRF3/beta-actin ratio (Fig. 5C), indicating that enhanced expression of IRF3 effectively blocks new prion infection.
DISCUSSION
In the present study, we found that a geneticdeficiency of IRF3 accelerates the progression of TSE(transmissable prion disease) following i.p. transmission in mice and that the accumulation rate of PrPSc in the spleen is increased in the IRF3−/− mice. Furthermore, we demonstrated that IRF3 has an inhibitory effect on PrPSc accumulation and that the levels of IRF3 are inversely correlated withresistance to prion infection in cell culture.
IRF3 is known to be constitutively expressed in many tissues and cells (6, 22, 45). Indeed, we confirmed the expression of IRF3 in brains (data not shown) and N2a58 cells (Fig. 5). Furthermore, not only glial cells but also neurons express most innate immunity-related genes and produce type I IFN in response to virus infection (11). Although the role of IRF3 in prion propagation into the CNS is still unclear, we speculate that an absence of IRF3 signaling leads to increased prion replication not only in peripheral tissues but also in the CNS. It would be of great value to examine this further using neuron-specific IRF3-disrupted mice or neuron-specific IRF3-expressing mice.
It was reported in prion infection that genetic disturbance of TLR4 (36) or interleukin-10 (IL-10) (41) leads to shorter incubation periods of prion infection. Since these, respectively, are an upstream and a downstream factor of the IRF3-mediated pathway, the findings may be due in part to functional changes in IRF3-mediated signaling.
Based on these results, two hypothetical models are proposed to explain the inhibitory effect of IRF3 on the prion infection. The first is that MyD88-independent pattern recognition receptors (PRRs), such as TLR3, TLR4, or RIG-I/MDA5, might recognize prion, and the resulting activation of IRF3 could induce various IRF3-responsive genes that may participate in the protective effect. The fact that the in vivo administration of IFNs (interferons), a representative of the IRF3-responsive genes,previously failed to show inhibitory effects on TSE (13, 16) suggests that IRF3-responsive genes other than IFNs may be important for the inhibitory effect of IRF3 on prion infection. Of note, the protective effect of IRF3 against several viruses has been suggested to be largely independent of the production of type I IFN and is probably responsible for the antiviral actions of specific IRF3-responsive genes (10, 18, 21). Peritoneal macrophages from wild-type mice moderately induced tumor necrosis factor alpha (TNF-α) or IL-6 following exposure to PrPSc-mimicking PrP peptides (PrP residues 106 to 126 or PrP residues 118 to 135), whereasTLR4 signaling-mutant mice were impaired in their ability to produce these cytokines (36), supporting in part the hypothesis that some PRRs may sense PrPSc as a sort of PAMP. On the other hand, it should be noted that the MyD88-independent pathway activates both NF-κB and IRF3. Although the induction of proinflammatory cytokines essentially depends upon NF-κB, it was unclear whether the activation of IRF3 was induced by these PrP peptides. In fact, the hallmarks of IRF3 activation, such as phosphorylation, dimerization, and cytoplasm-to-nucleus translocation of IRF3 in 22L-N2a58 cells, were not detected (data not shown). Moreover, it was previously reported that IFNs were not detected in the serum, spleens, or brains of mice infected with scrapie (44). In addition, IFN-β mRNA does not increase in the brains of CJD (human prion disease) patients (7) or mice infected with ME7 prion strain (14). Hence, these results argue against the notion that the IRF3-mediated signaling is activated by prion infection, but it remains to be determined whether transient and weak responses are evoked at an early phase in the infection. The question as to whether IRF3-mediated signaling directly suppresses the production of PrPSc or increases its degradation also remains open.
Another explanation is that prion infection itself may have little effect on the pathway but that the basal activity of IRF3 may have some degree of inhibitory effect on prion propagation. It has been reported that IRF3 can be activated not only by viruses but also by multiple activators such as cellular stress and DNA damage (24, 34). Accordingly, it is possible that constitutive activation of IRF3, albeit at a low level, occurs in the brain even in the absence of a pathogen. This notion is further supported by the fact that constitutive,weak IFN signaling in the absence of viral infection plays a role in modifying cellular responsiveness in the immune and other biological systems (38, 40). Accumulating evidence indicates that many viruses have evolved to evade the innate immune system, including IRF3-mediated signaling (15, 23). For instance, an active mutant of IRF3 has been reported to exert a markedly suppressive effect on cellular HIV-1 infection, and administration of poly(I·C) potently inhibits HIV-1 replication in microglia through a pathway requiring IRF3. Nonetheless, HIV-1 itself does not activate IRF3 but, rather, decreases IRF3 protein in HIV-1-infected cells (12, 37). Likewise, prion infection might disturb the activation of IRF3 even though prion is considered to be largely composed of PrPSc. We are currently investigating this possibility. Furthermore, an analogy can be made between the role of IRF3 in prion infection and that of IL-10. The levels of IL-10 are not increased in the brains of scrapie-infected mice (14, 42), whereas IL-10 knockout mice are highly susceptible to the development of scrapie (41).
In conclusion, we have shown that IRF3, a key transcription factor of the MyD88-independent pathways, operates in the host defense machinery against prion infection. The findings provide new insight into understanding of the innate immunity to prion infection.
Interleukin-10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, IL-10 is encoded by the IL10 gene.[1]
Gene and protein structure
The IL-10 protein is a homodimer; each of its subunits is 178-amino-acid long.[2]
IL-10 is classified as a class-2 cytokine, a set of cytokines including IL-19, IL-20, IL-22, IL-24 (Mda-7), and IL-26, interferons (IFN-alpha, -beta, -epsilon, -kappa, -omega, -delta, -tau, and -gamma)and interferon-like molecules (limitin, IL-28A, IL-28B, and IL-29).[3]
Expression and synthesis
In humans, IL-10 is encoded by the IL10 gene, which is located on chromosome 1 and comprises 5 exons,[1] and is primarily produced by monocytes and, to a lesser extent, lymphocytes, namelytype 2 T helper cells (TH2), mastocytes, CD4+CD25+Foxp3+regulatory T cells, and in a certain subset of activated T cells and B cells.
In biochemistry, a dimer is a macromolecular complex formed by two, usually non-covalently bound, macromolocules like proteins or nucleic acids. It is a quaternary structure of a protein.
A homo-dimer would be formed by two identical molocules (a process called homodimerization). A hetero-dimer would be formed by two different macromolecules (called heterodimerization).
Most dimers in biochemistry are not connected by covalent bonds. An example of a non-covalent heterodimer would be the enzyme reverse transcriptase, which is composed of two different amino acid chains.[1] An exception is dimers that are linked by disulfide bridgessuch as the homodimeric protein NEMO.[2]
Some proteins contain specialized domains to ensure dimerization (dimerization domains).
Examples of Homodimer include anti-bodies and Factor VII.
Microglia are a type of glial cell that are the resident macrophages of the brain and spinal chord,and thus act as the first and main form of active immune defense in the central nervous system (CNS).
Microglia constitute 10-15% of the total glial cell population within the brain.[1] Microglia (and astrocytes) are distributed in large non-overlapping regions throughout the brain and spinal cord.[2][3]Microglia are constantly scavenging the CNS for plaques, damaged neurons and infectious agents.[4]The brain and spinal cord are considered “immune privileged” organs in that they are separated from the rest of the body by a series of endothelial cells known as the blood-brain barrier, which prevents most infections from reaching the vulnerable nervous tissue. In the case where infectious agents are directly introduced to the brain or cross the blood–brain barrier, microglial cells must react quickly to decrease inflammation and destroy the infectious agents before they damage the sensitive neural tissue. Due to the unavailability of antibodies from the rest of the body (few antibodies are small enough to cross the blood brain barrier), microglia must be able to recognize foreign bodies, swallow them, and act as antigen-presenting cells activating T-cells. Since this process must be done quickly to prevent potentially fatal damage, microglia are extremely sensitive to even small pathological changes in the CNS.[5] They achieve this sensitivity in part by having unique potassium channels that respond to even small changes in extracellular potassium.
Microglial cells differentiate in the bone marrow from hematopoietic stem cells, the progenitors of all blood cells. During hematopoiesis, some of these stem cells differentiate into monocytes and travel from the bone marrow to the brain, where they settle and further differentiate into microglia.[6]
Monocytes can also differentiate into myeloid dendritic cells and macrophages in the peripheral systems. Like macrophages in the rest of the body, microglia use phagocytic and cytotoxic mechanisms to destroy foreign materials. Microglia and macrophagesboth contribute to the immune response by acting as antigen presenting cells, as well as promoting inflammation and homeostatic mechanisms within the body by secreting cytokines and other signaling molecules.
In their downregulated form, microglia lack the MHC class I/MHC class II proteins, IFN-γ cytokines, CD45 antigens, and many other surface receptors required to act in the antigen-presenting, phagocytic, and cytotoxic roles that hallmark normal macrophages. Microglia also differ from macrophages in that they are much more tightly regulated spatially and temporally in order to maintain a precise immune response.[7]
Another difference between microglia and other cells that differentiate from myeloid progenitor cells is the turnover rate. Macrophages and dendritic cells are constantly being used up and replaced by myeloid progenitor cells which differentiate into the needed type. Due to the blood brain barrier, it would be fairly difficult for the body to constantly replace microglia. Therefore, instead of constantly being replaced with myeloid progenitor cells, the microglia maintain their status quo while in their quiescent state, and then, when they are activated, they rapidly proliferate in order to keep their numbers up. Bone chimera studies have shown, however, that in cases of extreme infection the blood-brain barrier will weaken, and microglia will be replaced with haematogenous, cart-marrow derived cells, namely myeloid progenitor cells and macrophages. Once the infection has decreased the disconnect between peripheral and central systems is reestablished and only microglia are present for the recovery and regrowth period.
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Transport of prion protein across the blood–brain barrier
Abstract
The cellular form of the prion protein (PrPc) is necessary for the development of prion diseases and is a highly conserved protein that may play a role in neuroprotection. PrPc is found in both blood and cerebrospinal fluid and is likely produced by both peripheral tissues and the central nervous system (CNS). Exchange of PrPc between the brain and peripheral tissues could have important pathophysiologic and therapeutic implications, but it is unknown whether PrPc can cross the blood–brain barrier (BBB). Here, we found that radioactively labeled PrPccrossed the BBB in both the brain-to-blood and blood-to-brain directions. PrPc was enzymatically stable in blood and in brain, was cleared by liver and kidney, and was sequestered by spleen and the cervical lymph nodes. Circulating PrPc entered all regions of the CNS, but uptake by the lumbar and cervical spinal cord, hypothalamus, thalamus, and striatum was particularly high. These results show that PrPc has bidirectional, saturable transport across the BBB and selectively targets some CNS regions. Such transport may play a role in PrPc function and prion replication.
Introduction
Cellular prion protein (PrPc) is perhaps best known as a source for the misfolded protein PrPsc (Prusiner, 1997) and as a prerequisite for the development of prion diseases (Mallucci et al., 2000). However, PrPc itself likely has important biological functions. It is found circulating in blood (Volkel et al., 2001) and is found in even higher levels in the cerebrospinal fluid (CSF) (Picard-Hagen et al., 2006). After ischemic events, PrPc levels increase in blood (Mitsios et al., 2007) and in neurons and brain endothelial cells in the peri-infarct region (Mitsios et al., 2007; Weise et al., 2004). These increases may reflect cytoprotective and neuroprotective roles for PrPc as recently reviewed (Roucou & LeBlanc, 2005). PrPc null mice have larger infarct volumes after ischemic events (Weise et al., 2006; Nasu-Nishimura et al., 2008) and more neuronal apoptosis after viral infections (Nasu-Nishimura et al., 2008) than wild type mice. In comparison, mice that overexpress PrPc have smaller infarcts and better neurological outcomes than wild type mice after ischemic events (Shyu et al., 2005). These protective events are likely mediated by PrPc through activation of anti-apoptotic (Spudich et al., 2005) and anti-oxidant pathways (White et al., 1999).
Sources of circulating PrPc likely include platelets (Robertson et al., 2006), endothelial cells (Simak et al., 2002), and lymphocytes (Politopoulou et al., 2000). Among lymphocytes, CD3 and CD8 lymphocytes have especially high levels which increase with aging (Politopoulou et al., 2000). All these cells have membrane bound PrPc that apparently can be released into the circulation. Platelet activation (Robertson et al., 2006) or endothelial apoptosis (Simak et al., 2002), for example, results in release of PrPc from those cells.
Thus, PrPc occurs in both blood and in CSF with levels that are likely responsive to disease states. This raises the question of whether PrPc can cross the blood–brain barrier (BBB). Such passage could link the two pools of PrPc and the events that control their levels. Here, we examined the ability of PrPc to cross the BBB in both the blood-to-brain and the brain-to-blood directions.
Capillary depletion
Capillary depletion as modified for use in the mouse (Triguero et al., 1990; Gutierrez et al., 1993) was used to determine the degree to which PrPc was sequestered and retained by the vascular bed of the brain.
I-PrPc was also taken up by the peripheral tissues of spleen, liver, kidney and cervical lymph nodes (Table 2)… there was a statistically significant decrease in the Ki for brain: F(1,8) = 7.97, p <0.05. This demonstrates that transport of PrPc across the BBB involves a saturable transport system.
Fig. 4 shows values for brain and spinal cord regions. Statistical comparison of the whole brain value to brain regions and olfactory bulb (spinal cord regions excluded) showed a statistically significant variation: F(22,62) = 18.3, p <0.001. The hypothalamus, thalamus, and striatum showed statistically (p <0.01) greater uptake in comparison to whole brain. The highest uptake, however, was into the lumbar region of the spinal cord. Inhibition of uptake by unlabeled PrPc (Table 3; p <0.05) was found for whole brain, olfactory bulb, 4 of the 10 brain regions (occipital cortex, thalamus, striatum, and midbrain) and two of the spinal cord regions (cervical and lumbar)…
Fig. 5 Brain-to-blood efflux of PrPc after icv injection. Half-time clearance from brain was 15.7 min. Inset shows that inclusion of unlabeled PrPc in the icv injection increased retention of radioactively labeled PrPc by brain, demonstrating a saturable component…
Does aluminum in vaccines have a more sinister plot that is stated?
Differential effect of aluminum on the blood-brain barrier transport of peptides, technetium and albumin.
Abstract
Aluminum is a neurotoxin capable ofaltering membrane structure and function. We investigated whether aluminum also can affect saturable transport across membranes using the blood-brain barrier as our model. Mice were given i.p. or i.v. aluminum (up to 100 mg/kg) as the chloride salt and the disappearance from the brain of several centrally administered substances was measured. We found that aluminum rapidly and profoundly inhibited the saturable system that transports the small, N-tyrosinated peptides Tyr-MIF-1 and the enkephalins from the brain to the blood by acting as a noncompetitive inhibitor. In contrast, the disappearance from the brain of technetium pertechnetate (a substance also transported out of the brain by a different saturable system), albumin or D-Tyr-MIF-1 (a stereoisomer of Tyr-MIF-1 that was confirmed not to be transported by the carrier system) was not affected by aluminum. Aluminum also did not alter either the saturable or nonsaturable component of the uptake of Tyr-MIF-1 by erythrocytes. These findings suggest that one mechanism by which aluminum may induce neurotoxicity is byselective alteration of the transport systems of the blood-brain barrier.
An enkephalin is a pentapeptide involved in regulating nociception in the body. The enkephalins are termed endogenous ligands, as they are internally derived and bind to the body’s opioid receptors. Discovered in 1975, two forms of enkephalin were revealed, one containing leucine (“leu”), and the other containing mathione (“met”). Both are products of the proenkephalin gene.
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Endogenous opioid peptides
There are three well-characterized families of opioid peptides produced by the body: enkephalins, endorphines, and dynorphins. The met-enkephalin peptide sequence is coded for by the enkephalin gene; the leu-enkephalin peptide sequence is coded for by both the enkephalin gene and the dynorphin gene.[3] The proopiomelanocortin gene (POMC) also contains the met-enkephalin sequence on the N-terminus of beta-endorphin, but the endorphin peptide is not processed into enkephalin.
Enkephalin receptor
Main article: Opioid recepter
The receptors for enkephalin are the delta opioid receptors. Opioid receptors are a group of G-protein-coupled receptors, with other opioids as ligands as well. The other endogenous opioids are dynorphins (that bind to kappa receptors), endorphines (mu receptors), endomorphins, and nociceptin/orphanin FQ. The opioid receptors are ~40% identical to somatostatin receptors (SSTRs).
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Endomorphins, Met-Enkephalin, Tyr-MIF-1, and the P-glycoprotein Efflux System
Abstract
The P-glycoprotein (P-gp) transport system, responsible for the efflux of many therapeutic drugs out of the brain, recently has been shown to transport the endogenous brain opiate endorphin. We used P-gp knockout mice (Mdr1a) and their controls to determine where P-gp is involved in the saturable efflux systems of four other endogenous opiate-modulating peptides across the blood-brain barrier (BBB). After injection of endomorphin-1 (Tyr-Pro-Trp-Phe-NH2), endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), Met-enkephalin (Tyr-Gly-Gly-Phe-Met-OH), and Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) into the lateral ventricle of the mouse brain, residual radioactivity was measured at 0, 2, 5, 10, and 20 min later. The results showed no difference in the disappearance of any of these peptides from the brains of knockout mice compared with their controls. This demonstrates that unlike endorphin and morphine, P-gp does not seem to be required for the brain-to-blood transport of the endomorphins, Met-enkephalin, or Tyr-MIF-1 across the BBB.
Footnotes
This work was supported by the United States Army Medical Research Acquisition Activity (DAMD17-00-0113) and the Department of Veterans Affairs.
Endorphins (“endogenous morphine”) are endogenous opioid inhibitory neuropeptides. They are produced by the central nervous system and pituitary gland. The term implies a pharmacological activity (analogous to the activity of the corticosteroid category of biochemicals) as opposed to a specific chemical formulation. It consists of two parts: endo- and -orphin; these are short forms of the words endogenous and morphine, intended to mean “a morphine-like substance originating from within the body.”[1]
History
Opioid neuropeptides were first discovered in 1974 by two independent groups of investigators:
John Hughes and Hans Kosterlitz of Scotland isolated — from the brain of a pig — what some called enkephalins (from the Greek εγκέφαλος, cerebrum).[2][3]
Around the same time, in a calf brain, Rabi Simantov and Solomon H. Snyder of the United States found[4] what Eric Simon (who independently discovered opioid receptors in vertebral brains) later termed “endorphin” by an abreviation of of “endogenous morphine”, meaning “morphine produced naturally in the body”.[1] Importantly, recent studies have demonstrated that human and diverse animal tissues are in fact capable of producing morphine itself, which is not a peptide.[5][6]
Mechanism of action
Beta-endorphin (β-endorphin) is released into blood from the pituitary gland and into the spinal cord and brain from hypothalamic neurons. The β-endorphin that is released into the blood cannot enter the brain in large quantities because of the blood-brain barrier, so the physiological importance of the β-endorphin that can be measured in the blood is far from clear. β-endorphin is a cleavage product of pro-opiomelanocortin (POMC), which is also the precursor hormone for adrenocorticotrophic hormone (ACTH). The behavioural effects of β-endorphin is exerted by its actions in the brain and spinal cord, and it is presumed that the hypothalamic neurons are the major source of β-endorphin at those sites. In situations where the level of ACTH is increased (e.g., Cushing’s disease), the level of β-endorphin also increases slightly.
β-endorphin has the highest affinity for the μ1 opioid receptor, slightly lower affinity for the μ2 and δ opioid receptors, and low affinity for the κ1 opioid receptors. μ-Opioid receptors are the main receptor through which morphine acts. In the classical sense, μ opioid receptors are presynaptic, and inhibit neurotransmitter release. Through that mechanism, they inhibit the release of the inhibitory neurotransmitter GABA, and disinhibit the dopamine pathways, causing more dopamine to be released. By hijacking this process, exogenous opioids cause inappropriate dopamine release, and can lead to aberrant synaptic plasticity, which can cause dependency. Opioid receptors have many other and more important roles in the brain and periphery; however, modulating pain, cardiac, gastric and vascular function as well as possibly panic and satiation. Also, receptors are often found at postsynaptic locations as well as at presynaptic locations…
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Morphine preconditioning reduces lipopolysaccharide and interferon-γ-induced mouse microglial cell injury via δ1 opioid receptor activation
Abstract
Microglial cells play an important role in the inflammatory response of a broad range of brain diseases including stroke, brain infection and neurodegenerative diseases. However, there is very little information regarding how to protect microglial cells. Here, we showed that incubation of the C8-B4 mouse microglial cells with lipopolysaccharide (LPS) plus interferon-γ (IFNγ) induced cytotoxicity as assessed by the amount of lactate dehydrogenase (LDH) released from the cells. Preconditioning the cells with morphine for 30 min concentration-dependently reduced LPS plus IFNγ-induced cell injury. This morphine preconditioning effect was abolished by naloxone, a general opioid receptor antagonist, by naltrindole, a selective δ opioid receptor antagonist and by 7-benzylidenenaltrexone maleate, a selective δ1 opioid receptor antagonist. However, this protective effect was not affected by β-funaltrexamine, a selective μ opioid receptor antagonist, nor-binaltorphimine, a selective κ opioid receptor antagonist or naltriben, a selective δ2 opioid receptor antagonist. LPS plus IFNγ induced the expression of inducible nitric oxide synthase (iNOS), which was not affected by morphine preconditioning. Our results suggest that morphine induced a preconditioning effect in microglial cells. This effect may be mediated by δ1 opioid receptors and may not be through inhibiting the expression of iNOS, a potentially harmful protein.
Prion peptide PrP106-126 induces inducible nitric oxide synthase (iNOS) and proinflammatory cytokine gene expression through the activation of NF-kB in macrophage cells
The inflammatory response in prion diseases is dominated by microglia activation. The molecular mechanisms that lie behind this inflammatory process are not very well understood. In the present study, we examined the activation of nuclear factor-kappa B (NF-κB) upon exposure to PrP106-126 and its role in PrP106-126-induced upregulation of inducible nitric oxide synthase (iNOS) and proinflammatory cytokines (interleukin [IL]-1β, tumor necrosis factor [TNF]-α, IL-6) in Ana-1 macrophages. The results showed that iNOS and proinflammatory cytokine release was significantly elevated in Ana-1 macrophages upon exposure to PrP106-126; that PrP106-126 treatment led to a significant NF-κB activation; that proinflammatory cytokines gene expression was elevated in macrophages upon exposure to PrP106-126; and that NF-κB inhibition significantly abrogated PrP106-126-induced upregulation of iNOS and inflammatory cytokine mRNA expression. These results suggest that treatment with neurotoxic prion peptides leads to the activation of transcription factor NF-κB, which in turn stimulates gene expression of iNOS and proinflammatory cytokines in Ana-1 macrophages.
The Transcription Factor Nuclear Factor-kappa B and Cancer
Abstract
Since the discovery of nuclear factor-kappa B (NF-κB) in 1986, many studies have been conducted showing the link between the NF-κB signalling pathway and control of the inflammatory response. Today it is well known that control of the inflammatory response and apoptosis is closely related to the activation of NF-κB. Three NF-κB activation pathways exist. The first (the classical pathway) is normally triggered in response to microbial and viral infections or exposure to pro-inflammatory cytokines that activate the tripartite IKK complex, leading to phosphorylation-induced IκB degradation and depends mainly on IKKβ activity. The second (the alternative pathway), leads toselective activation of p52:RelB dimers by inducing the processing of the NF-κB2/p100 precursor protein, which mostly occurs as a heterodimer with RelB in the cytoplasm. This pathway is triggered by certain members of the tumour necrosis factor cytokine family, through selective activation of IKKα homodimers by the upstream kinase NIK. The third pathway is named CK2 and is IKK independent. NF-κB acts through the transcription of anti-apoptotic proteins, leading to increased proliferation of cells and tumour growth. It is also known that some drugs act directly in the inhibition of NF-κB, thus producing regulation of apoptosis; some examples are aspirin and corticosteroids. Here we review the role of NF-κB in the control of apoptosis, its link to oncogenesis, the evidence of several studies that show that NF-κB activation is closely related to different cancers, and finally the potential target of NF-κB as cancer therapy.
Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology
Highlights
• NF-κB signaling in MS patients and animal models of MS.
• NF-κB signaling controls peripheral immune activation at multiple levels.
• NF-κB controls inflammatory responses locally in the CNS.
• NF-κB as a therapeutic target for the treatment of MS.
The nuclear factor kappa B (NF-κB) signaling cascade plays a critical role in the regulation of immune and inflammatory responses and has been implicated in the pathogenesis of autoimmune demyelinating diseases such as multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), the main animal model of MS. NF-κB is essential for peripheral immune cell activation and the induction of pathology, but also plays crucial roles in resident cells of the central nervous system (CNS) during disease development. Here we review recent evidence clarifying the role of NF-κB in the different cell compartments contributing to MS pathology and its implications for the development of therapeutic strategies for the treatment of MS and other demyelinating pathologies of the CNS.
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet radiation, oxidized LDL, and bacterial or viral antigens.[1][2][3][4][5] NF-κB plays a key role in regulating the immune response to infection (k light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory, and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory.[6][7][8][9][10]
In brief, NF-κB can be understood to be a protein responsible for cytokine production and cell survival.
Structure
All proteins of the NF-κB family share a Rel homology domain in their N-terminus. A subfamily of NF-κB proteins, including RelA, RelB, and c-Rel, have a transactivation domain in their C-termini. In contrast, the NF-κB1 and NF-κB2 proteins are synthesized as large precursors, p105, and p100, which undergo processing to generate the mature NF-κB subunits, p50 and p52, respectively. The processing of p105 and p100 is mediated by the ubiquitin/proteasome pathway and involves selective degradation of their C-terminal region containing ankyrin repeats. Whereas the generation of p52 from p100 is a tightly regulated process, p50 is produced from constitutive processing of p105.[12][13] The p50 and p52 proteins have no intrinsic ability to activate transcription and thus have been proposed to act as transcriptional repressors when binding κB elements as homodimers.[14][15] Indeed, this confounds the interpretation of p105-knockout studies, where the genetic manipulation is removing an IκB (full-length p105) and a likely repressor (p50 homodimers) in addition to a transcriptional activator (the RelA-p50 heterodimer).
Members
NF-κB family members share structural homology with the retroviral oncoprotein v-Rel, resulting in their classification as NF-κB/Rel proteins.[1]
There are five proteins in the mammalian NF-κB family:[16]
Species distribution and evolution
In addition to mammals, NF-κB is found in a number of simple animals as well.[17] These include cnidarians (such as sea anemones, coral and hydra), porifera (sponges), the single-celled eukaryote Capsaspora owczarzaki and insects (such as moths, mosquitoes, and fruit flies). The sequencing of the genomes of the mosquitoes A. aegypti and A. gambiae, and the fruitfly D. melangaster has allowed comparative genetic and evolutionary studies on NF-κB. In those insect species, activation of NF-κB is triggered by the Toll pathway (which evolved independently in insects and mammals) and by the Imd (immune deficiency) pathway.[18]
Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single, membrane-spanning, non-catalytic receptors usually expressed in sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes. Once these microbes havebreached physical barriers such as the skin or intestinal tract mucosa, they are recognized by TLRs, which activate immune cell responses…
Signaling
Activation
NF-κB (green) heterodimerizes with RelB (cyan) to form a ternary complex with DNA (orange) that promotes gene transcription.[19]
NF-κB is important in regulating cellular responses because it belongs to the category of “rapid-acting” primary transcription factors, i.e., transcription factors that are present in cells in an inactive state and do not require new protein synthesis in order to become activated (other members of this family include transcription factors such as c-Jun, STATs, and nuclear hormone receptors). This allows NF-κB to be a first responder to harmful cellular stimuli. Known inducers of NF-κB activity are highly variable and include reactive oxygen species (ROS), tumor necrosis factor alpha (TNFa), interleukin 1-beta (IL1β), bacterial lipopolysaccharides (LPS), isoproterenol, cocaine, and ionizing radiation.[20]
Receptor activator of NF-κB (RANK), which is a type of TNFR, is a central activator of NF-κB. Osteoprotegerin (OPG), which is a decoy receptor homolog for RANK ligand, inhibits RANK by binding to RANKL, and, thus, osteoprotegerin is tightly involved in regulating NF-κB activation.[21]
Many bacterial products and stimulation of a wide variety of cell-surface receptors lead to NF-κB activation and fairly rapid changes in gene expression.[1] The identification of Toll-like receptors(TLRs) as specific pattern recognition molecules and the finding that stimulation of TLRs leads to activation of NF-κB improved our understanding of how different pathogens activate NF-κB. For example, studies have identified TLR4 as the receptor for the LPS component of Gram-negative bacteria.[22]TLRs are key regulators of both innate and adaptive immune responses.[23]
Unlike RelA, RelB, and c-Rel, the p50 and p52 NF-κB subunits do not contain transactivation domains in their C terminal halves. Nevertheless, the p50 and p52 NF-κB members play critical roles in modulating the specificity of NF-κB function. Although homodimers of p50 and p52 are, in general, repressors of κB site transcription, both p50 and p52 participate in target gene transactivation by forming heterodimers with RelA, RelB, or c-Rel.[24] In addition, p50 and p52 homodimers alsobind to the nuclear protein Bcl-3, and such complexes can function as transcriptional activators.[25][26][27]
Inhibition
In unstimulated cells, the NF-κB dimers are sequestered in the cytoplasm by a family of inhibitors, called IκBs (Inhibitor of κB), which are proteins that contain multiple copies of a sequence called ankyrin repeats. By virtue of their ankyrin repeat domains, the IκB proteins mask the nuclear localization signals (NLS) of NF-κB proteins and keep them sequestered in an inactive state in the cytoplasm.[28]
IκBs are a family of related proteins that have an N-terminal regulatory domain, followed by six or more ankyrin repeats and a PEST domain near their C terminus. Although the IκB family consists of IκBα, IκBβ, IκBε, and Bcl-3, the best-studied and major IκB protein is IκBα. Due to the presence of ankyrin repeats in their C-terminal halves, p105 and p100 also function as IκB proteins. The c-terminal half of p100, that is often referred to as IκBδ, also functions as an inhibitor.[29][30] IκBδ degradation in response to developmental stimuli, such as those transduced through LTβR, potentiate NF-κB dimer activation in a NIK dependent non-canonical pathway.[29][31]
Activation of the NF-κB is initiated by the signal-induced degradation of IκB proteins. This occurs primarily via activation of a kinase called the IκB kinase (IKK). IKK is composed of a heterodimer of the catalytic IKKα and IKKβ subunits and a “master” regulatory protein termed NEMO (NF-κB essential modulator) or IKK gamma. When activated by signals, usually coming from the outside of the cell, the IκB kinase phosphorylates two serine residues located in an IκB regulatory domain. When phosphorylated on these serines (e.g., serines 32 and 36 in human IκBα), the IκB inhibitor molecules are modified by a process called ubiquitination, which then leads them to be degraded by a cell structure called the proteasome.
With the degradation of IκB, the NF-κB complex is then freed to enter the nucleus where it can ‘turn on’ the expression of specific genes that have DNA-binding sites for NF-κB nearby. The activation of these genes by NF-κB then leads to the given physiological response, for example, an inflammatory or immune response, a cell survival response, or cellular proliferation. NF-κB turns on expression of its own repressor, IκBα. The newly synthesized IκBα then re-inhibits NF-κB and, thus, forms an auto feedback loop, which results in oscillating levels of NF-κB activity.[32] In addition, several viruses, including the AIDS virus HIV, have binding sites for NF-κB that controls the expression of viral genes, which in turn contribute to viral replication or viral pathogenicity. In the case of HIV-1, activation of NF-κB may, at least in part, be involved in activation of the virus from a latent, inactive state.[33]YopP is a factor secreted by Yersinia pestis, the causative agent of plague, that prevents the ubiquitination of IκB. This causes this pathogen to effectively inhibit the NF-κB pathway and thus block the immune response of a human infected with Yersinia.[34]
Inhibitors of NF-κB activity
Concerning known protein inhibitors of NF-κB activity, one of them is IFRD1, which represses the activity of NF-κB p65 by enhancing the HDAC-mediated deacetylation of the p65 subunit at lysine 310, by favoring the recruitment of HDAC3 to p65. In fact IFRD1 forms trimolecular complexes with p65 and HDAC3.[35][36]
Non-canonical
A select set of cell-differentiating or developmental stimuli, such as lymphotoxin-α, BAFF or RANKL, activate the non-canonical NF-κB pathway to induce NF-κB/RelB:p52 dimer in the nucleus. In this pathway, activation of the NF-κB inducing kinase (NIK) upon receptor ligation led to the phosphorylation and subsequent proteasomal processing of the NF-κB2 precursor protein p100 into mature p52 subunit in an IKK1/IKKa dependent manner. Then p52 dimerizes with RelB to appear as a nuclear RelB:p52 DNA binding activity and regulate a distinct class of genes.[37] In contrast to the canonical signaling that relies upon NEMO-IKK2 mediated degradation of IκBα, -β, -ε, the non-canonical signaling critically depends on NIK mediated processing of p100 into p52. Given their distinct regulations, these two pathways were thought to be independent of each other. However, recent analyses revealed that synthesis of the constituents of the non-canonical pathway, viz RelB and p52, is controlled by the canonical IKK2-IκB-RelA:p50 signaling.[38] Moreover, generation of the canonical and non-canonical dimers, viz RelA:p50 and RelB:p52, within the cellular milieu are also mechanistically interlinked.[38] These analyses suggest that an integrated NF-κB system network underlies activation of both RelA and RelB containing dimer and that a malfunctioning canonical pathway will lead to an aberrant cellular response also through the non-canonical pathway.
In immunity
NF-κB is a major transcription factor that regulates genes responsible for both the innate and adaptive immune response. Upon activation of either the T- or B-cell receptor, NF-κB becomes activated through distinct signaling components. Upon ligation of the T-cell receptor, protein kinase Lck is recruited and phosphorylates the ITAMs of the CD3 cytoplasmic tail. ZAP70 is then recruited to the phosphorylated ITAMs and helps recruit LAT and PLC-γ, which causes activation of PKC. Through a cascade of phosphorylation events, the kinase complex is activated and NF-κB is able to enter the nucleus to upregulate genes involved in T-cell development, maturation, and proliferation.[39]
In the nervous system
In addition to roles in mediating cell survival, studies by Mark Mattson and others have shown that NF-κB has diverse functions in the nervous system including roles in plasticity, learning, and memory. In addition to stimuli that activate NF-κB in other tissues, NF-κB in the nervous system can be activated by Growth Factors(BDNF, NGF) and synaptic transmission such as glutamate.[7] These activators of NF-κB in the nervous system all converge upon the IKK complex and the canonical pathway.
Recently there has been a great deal of interest in the role of NF-κB in the nervous system. Current studies suggest that NF-κB is important for learning and memory in multiple organisms including crabs,[9][10] fruit flies,[40] and mice.[7][8]NF-κB may regulate learning and memory in part by modulating synaptic plasticity,[6][41]synapse function,[40][42][43]as well as by regulating the growth of dendrites[44]and dendritic spines.[43]
Genes that have NF-κB binding sites are shown to have increased expression following learning,[8]suggesting that the transcriptional targets of NF-κB in the nervous system are important for plasticity. Many NF-κB target genes that may be important for plasticity and learning include growth factors (BDNF, NGF)[45] cytokines (TNF-alpha, TNFR)[46] and kinases (PKAc).[41]
Despite the functional evidence for a role for Rel-family transcription factors in the nervous system, it is still not clear that the neurological effects of NF-κB reflect transcriptional activation in neurons. Most manipulations and assays are performed in the mixed-cell environments found in vivo, in “neuronal” cell cultures that contain significant numbers of glia, or in tumor-derived “neuronal” cell lines. When transfections or other manipulations have been targeted specifically at neurons, the endpoints measured are typically electrophysiology or other parameters far removed from gene transcription. Careful tests of NF-κB-dependent transcription in highly purified cultures of neurons generally show little to no NF-κB activity.[47][48] Some of the reports of NF-κB in neurons appear to have been an artifact of antibody nonspecificity.[49] Of course, artifacts of cell culture—e.g., removal of neurons from the influence of glia—could create spurious results as well. But this has been addressed in at least two coculture approaches. Moerman et al.[50] used a coculture format whereby neurons and glia could be separated after treatment for EMSA analysis, and they found that the NF-κB induced by glutamatergic stimuli was restricted to glia (and, intriguingly, only glia that had been in the presence of neurons for 48 hours). The same investigators explored the issue in another approach, utilizing neurons from an NF-κB reporter transgenic mouse cultured with wild-type glia; glutamatergic stimuli again failed to activate in neurons.[51] Some of the DNA-binding activity noted under certain conditions (particularly that reported as constitutive) appears to result from Sp3 and Sp4 binding to a subset of κB enhancer sequences in neurons.[52]This activity is actually inhibited by glutamate and other conditions that elevate intraneuronal calcium. In the final analysis, the role of NF-κB in neurons remains opaque due to the difficulty of measuring transcription in cells that are simultaneously identified for type. Certainly, learning and memory could be influenced by transcriptional changes in astrocytes and other glial elements. And it should be considered that there could be mechanistic effects of NF-κB aside from direct transactivation of genes.
Clinical significance
Overview of signal transduction pathways involved in apoptosis.
Cancers
NF-κB is widely used by eukaryotic cells as a regulator of genes that control cell proliferation and cell survival. As such, many different types of human tumors have misregulated NF-κB: that is, NF-κB is constitutively active. Active NF-κB turns on the expression of genes that keep the cell proliferating and protect the cell from conditions that would otherwise cause it to die via apoptosis.
Defects in NF-κB results in increased susceptibility to apoptosis leading to increased cell death. This is because NF-κB regulates anti-apoptotic genes especially the TRAF1 and TRAF2 and, therefore, checks the activities of the caspase family of enzymes, which are central to most apoptotic processes.[53]
In tumor cells, NF-κB is active either due to mutations in genes encoding the NF-κB transcription factors themselves or in genes that control NF-κB activity (such as IκB genes); in addition, some tumor cells secrete factors that cause NF-κB to become active. Blocking NF-κB can cause tumor cells to stop proliferating, to die, or to become more sensitive to the action of anti-tumor agents. Thus, NF-κB is the subject of much active research among pharmaceutical companies as a target for anti-cancer therapy.[54]
However, caution should be exercised when considering anti-NF-κB activity as a broad therapeutic strategy in cancer therapy, even though convincing experimental data have identified NF-κB as a critical promoter of cancer development, creating a solid rationale for the development of antitumor therapy that suppresses NF-κB activity. Data have also shown that NF-κB activity enhances tumor cell sensitivity to apoptosis and senescence. In addition, it has been shown that canonical NF-κB is a Fas transcription activator and the alternative NF-κB is a Fas transcription repressor.[55] Therefore, NF-κB promotes Fas-mediated apoptosis in cancer cells, and thus inhibition of NF-κB may suppress Fas-mediated apoptosis to impair host immune cell-mediated tumor suppression.
Inflammation
Because NF-κB controls many genes involved in inflammation, it is not surprising that NF-κB is found to be chronically active in many inflammatory diseases, such as inflammatory bowel disease, arthritis, sepsis, gastritis, asthma, atherosclerosis[56] and others. It is important to note though, that elevation of some NF-κB inhibitors, such asosteoprotegerin(OPG), are associated with elevated mortality, especially fromcardiovascular diseases.[57][58] Elevated NF-κB has also been associated with schizophrenia.[59] Recently, NF-κB activation has been suggested as a possible molecular mechanism for the catabolic effects of cigarette smoke in skeletal muscle and sarcopenia.[60]
Non-drug inhibitors
Many natural products (including anti-oxidants) that have been promoted to have anti-cancer and anti-inflammatory activity have also been shown to inhibit NF-κB.[61][62] There is a controversial US patent (US patent 6,410,516)[63] that applies to the discovery and use of agents that can block NF-κB for therapeutic purposes. This patent is involved in several lawsuits, including Ariad v. Lilly. Recent work by Karin,[64] Ben-Neriah[65] and others has highlighted the importance of the connection between NF-κB, inflammation, and cancer, and underscored the value of therapies that regulate the activity of NF-κB.[66]
Extracts from a number of herbs and dietary plants are efficient inhibitors of NF-κB activation in vitro.[67][68][69]
The circumsporozoite protein of Plasmodium falciparum has been shown to be an inhibitor of NF-κB.[70]
As a drug target
Aberrant activation of NF-κB is frequently observed in many cancers. Moreover, suppression of NF-κB limits the proliferation of cancer cells. In addition, NF-κB is a key player in the inflammatory response. Hence methods of inhibiting NF-κB signaling has potential therapeutic application in cancer and inflammatory diseases.[71][72]
The discovery that activation of NF-κB nuclear translocation can be separated from the elevation of oxidant stress[73] gives an important hint to the development of strategies for NF-κB inhibition.
A new drug called denosumab acts to raise bone mineral density and reduce fracture rates in many patient sub-groups by inhibiting RANKL. RANKL acts through its receptor RANK, which in turn promotes NF-κB,[74] RANKL normally works by enabling the differentiation of osteoclasts from monocytes.
Disulfiram, olmesartan and dithiocarbamates can inhibit the nuclear factor-κB (NF-κB) signaling cascade.[75]
Anatabine’s antiinflammatory effects are claimed to result from modulation of NF-κB activity.[76] However the studies purporting its benefit use abnormally high doses in the millimolar range (similar to the extracellular potassium concentration), which are unlikely to be achieved in humans.
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NF-kB
Nuclear factor NF-kappa-B p105 subunit is a protein that in humans is encoded by the NFKB1 gene.[1]
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappaB (NF-kB) protein complex. NF-κB is a transcription factor that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NF-κB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions; over 200 known genes are targets of NF-κB in various cell types, under specific conditions. Inappropriate activation of NF-κB has been associated with a number of inflammatory diseases while persistent inhibition of NF-κB leads to inappropriate immune cell development or delayed cell growth.[2]
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Signal Transduction Through Prion Protein
The cellular prion protein PrPc is a glycosylphosphatidylinositol-anchored cell-surface protein whose biological function is unclear. We used the murine 1C11 neuronal differentiation model to search for PrPc-dependent signal transduction through antibody-mediated cross-linking. A caveolin-1–dependent coupling of PrPc to the tyrosine kinase Fyn was observed. Clathrin might also contribute to this coupling. The ability of the 1C11 cell line to trigger PrPc-dependent Fyn activation was restricted to its fully differentiated serotonergic or noradrenergic progenies. Moreover, the signaling activity of PrPc occurred mainly at neurites. Thus, PrPc may be a signal transduction protein.
Science 15 September 2000: Vol. 289 no. 5486 pp. 1925–1928 DOI:10.1126/science.289.5486.1925
A cellular gene encodes scrapie PrP 27-30 protein.
Abstract
A clone encoding PrP 27-30, the major protein in purified preparations of scrapie agent, was selected from a scrapie-infected hamster brain cDNA library by oligonucleotide probes corresponding to the N terminus of the protein. Southern blotting with PrP cDNA revealed a single gene with the same restriction patterns in normal and scrapie-infected brain DNA. A single PrP-related gene was also detected in murine and human DNA. PrP-related mRNA was found at similar levels in normal and scrapie-infected hamster brain, as well as in many other normal tissues. Using antisera against PrP 27-30, a PrP-related protein was detected in crude extracts of infected brain and to a lesser extent in extracts of normal brain. Proteinase K digestion yielded PrP 27-30 in infected brain extract, but completely degraded the PrP-related protein in normal brain extract. No PrP-related nucleic acids were found in purified preparations of scrapie prions, indicating that PrP 27-30 is not encoded by a nucleic acid carried within the infectious particles.
Identification of Chemoattractive Factors Involved in the Migration of Bone Marrow-Derived Mesenchymal Stem Cells to Brain Lesions Caused by Prions
ABSTRACT
Bone marrow-derived mesenchymal stem cells (MSCs) have been reported to migrate to brain lesions of neurodegenerative diseases; however, the precise mechanisms by which MSCs migrate remain to be elucidated. In this study, we carried out an in vitro migration assay to investigate the chemoattractive factors for MSCs in the brains of prion-infected mice. The migration of immortalized human MSCs (hMSCs) was reduced by their pretreatment with antibodies against the chemokine receptors, CCR3, CCR5, CXCR3, and CXCR4 and by pretreatment of brain extracts of prion-infected mice with antibodies against the corresponding ligands, suggesting the involvement of these receptors, and their ligands in the migration of hMSCs. In agreement with the results of an in vitro migration assay, hMSCs in the corpus callosum, which are considered to be migrating from the transplanted area toward brain lesions of prion-infected mice, expressed CCR3, CCR5, CXCR3, and CXCR4. The combined in vitro and in vivo analyses suggest that CCR3, CCR5, CXCR3, and CXCR4, and their corresponding ligands are involved in the migration of hMSCs to the brain lesions caused by prion propagation. In addition, hMSCs that had migrated to the right hippocampus of prion-infected mice expressed CCR1, CX3CR1, and CXCR4, implying the involvement of these chemokine receptors in hMSC functions after chemotactic migration. Further elucidation of the mechanisms that underlie the migration of MSCs may provide useful information regarding application of MSCs to the treatment of prion diseases.
INTRODUCTION
Prion diseases are fatal neurodegenerative disorders in humans and animals that are characterized by the accumulation of a disease-specific isoform of the prion protein (PrPSc), astrocytosis, microglial activation, spongiosis, and neuronal cell death in the central nervous system (CNS). Although the etiology of the diseases is not clear, conversion of the normal prion protein to PrPSc plays a key role in the neuropathological changes (44). Therefore, compounds that inhibit PrPSc formation are considered as therapeutic candidates of the diseases, and many compounds have been reported to inhibit PrPSc formation in cell cultures and cell-free systems (reviewed in reference 56). However, only a few of these inhibitors, such as amphotericin B and its derivative (13), pentosan polysulfate (14), porphyrin derivatives (27), certain amyloidophilic compounds (25), and FK506 (37) have been reported to prolong the survival of prion-infected mice even when administered in the middle-late stage of infection but still before clinical onset. We recently reported that intraventricular infusion of anti-PrP antibodies (50) slowed down the progression of the disease even when initiated just after clinical onset. However, in addition to inhibition of PrPSc formation, the protection of neurons or restoration of degenerated neurons is thought to be important for functional recovery.
Bone marrow-derived mesenchymal stem cells (MSCs) differentiate into cells of mesodermal origin such as adipocytes, osteoblasts, and endothelial and muscle cells (41, 43). In addition, MSCs are known to transdifferentiate into neuronal and glial cells. MSCs have been shown to migrate to damaged neuronal tissues and to alleviate the deficits in experimental animal models of cerebral ischemia (10), spinal cord injury (20), Parkinson’s disease (19, 33), and amyotrophic lateral sclerosis(59). MSCs also secrete various neurotrophic factors that may protect neuronal tissues from degradations, as well as stimulate the activity of endogenous neural stem cells (38). Therefore, despite their mesodermal origin, MSCs are considered to be a candidate for cell-mediated therapy for neurodegenerative diseases. One of the characteristics of MSCs is their migration to brain lesions caused by neurodegenerative diseases, including prion diseases (10, 19, 39, 51). This feature may be of further use for cell-mediated therapy of neurodegenerative diseases, particularly for prion diseases, Multiple sclerosis and Alzheimer’s disease, which have diffuse pathological lesions.
Since many cytokines, chemokines, and adhesion molecules are involved in the homing of immune cells (9, 36, 53), evidence that a variety of chemokines and growth factors, as well as their cognate receptors, have a pivotal role in the migration of MSCs has been accumulated. These factors include CXCL12 and its receptor CXCR4 (30, 40; reviewed in reference 52), CCL2 (15, 62, 66), CCL3 (62), interleukin-8 (48, 62), hepatocyte growth factor (16), platelet-derived growth factor AB (PDGF-AB), insulin-like growth factor 1 (IGF-1), CCL5 and CCL22 (42), and integrin β1 (23). Regarding the migration of MSCs to injury in the CNS, the involvement of CCL2 (61), CXCL12/CXCR4, and CX3CL1/CX3CR1 (24) has been reported. However, knowledge of the mechanism by which MSCs migrate to pathological lesions of neurodegenerative diseases is insufficient, and further efforts are required to elucidate this mechanism.
We recently reported that human MSCs (hMSCs) migrate to CNS lesions and prolong the survival of mice infected with prions (51). In the present study, we investigated factors that are involved in the migration of hMSCs to brain lesions of prion diseases.
To say that the body is one giant communication system is an understatement. The expression of genes and the ability for host cells to operate normally and to chemically call for help when faced with an antigen is esential to health. As discussed above, these prion interferors with the interferon and other defensive signaling processes must be injected to bypass the mucosus and the skin. This can only be accomplished through innoculation and vaccination.
The introduction of foreign proteins and DNA/RNA into the otherwise healthy body is certainly described here as the cause of most disease states in modern times. And from the time that this interferon was discovered, these psychopathic scientists have been working overtime to prevent our bodies from being able to fight what they inject.
What you have just read is the cause and cure for AIDS, cancers, dementias, and a host of other modern medically-induced disease states that revolve around prion infection and misfolding of the signal processing of the body. It is not so much a cure as an acknowledgement of the cause, for when disease is purposefully caused, the word cure seems trivial in practice, and allows the culprits to literally get away with murder.
It was caused by them…
Will we sit by helplessly and hope for a cure to these purposefully caused diseases by the very perpetrators of them?
Isn’t that the American way though?
For as we wait, they merely perfect their science of biological aggression and warfare…
(Note: all unlinked data as descriptions above from Wikipedia, which are well-sourced within that site.)
.
–Clint Richardson (realitybloger.wordpress.com)
–Thursday, December 4rth, 2014
A few months ago, I documented a speculative and fact-based op-ed that espoused my theory that most modern degenerative diseases referred to as “dementia” are at the very least partially caused by what are called prions – malformed or “folded” proteins that infectiously cause other proteins to fold and be rendered useless to the human body – causing disease states ranging from 50% of all cancers to AIDS as a protein “blood cancer” to mental disorders such as Alzheimer’s and ALS.
It is my sincere belief that these infectious prions are being spread either inadvertently or purposefully throughout the human and animal population through the use of animal and human DNA and proteins found after the growing and manufacture process for vaccines – the use of human diploid (aborted fetal) cells and animal organs, blood, and parts as cell substrate growth mechanisms for the culturing of vaccines. Prions are the cause of Mad-Cow Disease, as well as equivalent disease states in humans showing protein (prion) misfolding.
While a guy like me will never be considered for a Nobel Prize for such speculation and endless compiling of other people’s research, I will be chronicling any information that comes my way regarding this dyer theory.
Case in point…
On September 20, 2011, the Vancouver Coastal Health Research Institute posted the following article:
Dr. Neil Cashman PrioNet Canada researchers in Vancouver confirm prion-like properties in Amyotrophic Lateral Sclerosis (ALS)
September 20, 2011 – Vancouver, BC: A team of researchers from the University of British Columbia and the Vancouver Coastal Health Research Institute have found a key link between prions and the neurodegenerative disease ALS ( Amyotrophic Lateral Sclerosis), also known as Lou Gehrig’s disease. The discovery is significant as it opens the door to novel approaches to the treatment of ALS.
SOD-1 Dimer A pivotal paper published by the team this week in the Proceedings of the National Academy of Sciences (PNAS), demonstrates that the SOD1 protein (superoxide dismutase 1), which has been shown to be implicated in the ALS disease process, exhibits prion-like properties. The researchers found that SOD1 participates in a process called template-directed misfolding. This term refers to the coercion of one protein by another protein to change shape and accumulate in large complexes in a fashion similar to the process underlying prion diseases.
These findings provide a molecular explanation for the progressive spread of ALS through the nervous system, and highlight the central role of the propagation of misfolded proteins in the pathogenesis of neurodegenerative diseases, including ALS, Alzheimer’s and Parkinson’s.
“Our work has identified a specific molecular target, which when manipulated halts the conversion of the SOD1 protein to a misfolded, disease-causing form,” says Dr. Neil Cashman, Scientific Director of PrioNet Canada, Canada Research Chair in Neurodegeneration and Protein Misfolding at UBC, and academic director of the Vancouver Coastal Health ALS Centre. “This discovery is a first-step toward the development of targeted treatments that may stop progression of ALS.”
ALS is a progressive neuromuscular disease in which nerve cells die, resulting in paralysis and death. Approximately 2,500 to 3,000 Canadians currently live with this fatal disease, for which there is no effective treatment yet.
“For many years, ALS has remained a complex puzzle and we have found a key piece to help guide the research community to solutions,” says Dr. Leslie Grad, a co-first author of the project and current Manager of Scientific Programs at PrioNet Canada. “PrioNet is further exploring this discovery through newly-funded research projects.”
The work was completed by Dr. Neil Cashman’s lab at the Brain Research Centre based at the University of British Columbia and the Vancouver Coastal Health Research Institute, in collaboration with researchers at the University of Alberta. The research was supported by PrioNet Canada and in part by Amorfix Life Sciences and the Canadian Institutes of Health Research.
PrioNet Canada, based in Vancouver, has achieved international attention for scientific discoveries and risk management strategies directed at controlling prion diseases, and is now directing capacity into therapeutic solutions for prion-like diseases of aging, such as Alzheimer’s, Parkinson’s and ALS.
ABOUT:
One of Canada’s Networks of Centres of Excellence, PrioNet Canada (www.prionetcanada.ca) is developing strategies to help solve the food, health safety, and socioeconomic problems associated with prion diseases. The network brings together scientists, industry, and public sector partners through its multidisciplinary research projects, training programs, events, and commercialization activities. PrioNet is hosted by the University of British Columbia and the Vancouver Coastal Health Research Institute in Vancouver.
The University of British Columbia (UBC) is one of North America’s largest public research and teaching institutions, and one of only two Canadian institutions consistently ranked among the world’s 40 best universities. UBC is a place that inspires bold, new ways of thinking that have helped make it a national leader in areas as diverse as community service learning, sustainability and research commercialization. UBC offers more than 50,000 students a range of innovative programs and attracts $550 million per year in research funding from government, non-profit organizations and industry through 7,000 grants.
Vancouver Coastal Health Research Institute (VCHRI) (www.vchri.ca) is the research body of Vancouver Coastal Health Authority, which includes BC’s largest academic and teaching health sciences centres: VGH, UBC Hospital, and GF Strong Rehabilitation Centre. In academic partnership with the University of British Columbia, VCHRI brings innovation and discovery to patient care, advancing healthier lives in healthy communities across British Columbia, Canada, and beyond.
The Brain Research Centre (BRC) (www.brain.ubc.ca) comprises more than 200 investigators with multidisciplinary expertise in neuroscience research ranging from the test tube, to the bedside, to industrial spin-offs. The centre is a partnership of UBC and Vancouver Coastal Health Research Institute.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig ‘s disease in the United States and motor neurone disease (MND) in Europe, is a fatal neurodegenerative disease caused by deterioration of motor neurons in the brain and spinal cord. Individuals living with the disease experience progressive paralysis, as well as difficulty breathing or swallowing. At this time, no cure or effective treatment exists.
According to the ALS Society of Canada: ALS is the most common cause of neurological death Every day two or three Canadians die of ALS Eighty per cent of people with ALS die within two to five years of diagnosis; ten per cent of those affected may live for 10 years or longer Approximately 2,500 – 3,000 Canadians currently live with this fatal disease The World Health Organization predicts that neurodegenerative diseases will surpass cancer as the second leading cause of death in Canada by 2040
BACKGROUND:
Recent research highlights links between the biological mechanisms of common neurological disorders, such as ALS, Alzheimer’s and Parkinson’s disease with prion disease. While each of these diseases manifests itself in a different way, the hallmark of each is a progressive accumulation of misfolded protein aggregates in the central nervous system.
Correctly-folded proteins adopt one particular structure in order to carry out their intended function. A protein’s failure to adopt this correct structure is what threatens the health of cells. Prions are “misfolded” proteins – the infectious, aggregating agents in diseases such as Creutzfeldt-Jakob disease (CJD) in humans, chronic wasting disease (CWD) in deer and elk and bovine spongiform encephalopathy (BSE), also known as “mad cow” disease in cattle. In ALS, Alzheimer’s and Parkinson’s, the misfolded proteins are SOD1, amyloid-B and a-synuclein, respectively.
Key Finding:
“Intermolecular transmission of SOD-1 misfolding in living cells” – Published in the Proceedings of the National Academy of Sciences (PNAS), September 2011. The paper shows that superoxide dismutase 1 (SOD1) participates in template-directed misfolding, in other words, the coercion of one protein by another protein to change shape and aggregate such as prion diseases do. The results will be significant to the ALS field because it connects prion mechanisms behind the biological progression of ALS, and provides a molecular explanation for the linear and temporal spread of ALS through the nervous system. Furthermore, the research has identified a specific molecular target, which when manipulated, halts the conversion of SOD1 to a misfolded, disease-causing form. This is a first-step towards the development of targeted treatments that may stop ALS, which PrioNet is further exploiting through newly-funded research. This research was supported by PrioNet Canada and in part by Amorfix Life Sciences and the Canadian Institutes of Health Research.
Other Research:
Studies showing how “seed” misfolded protein induce aggregation of other protein, which provide evidence for prion-like spread: Lary Walker’s group at Emory University in Atlanta, in collaboration with Matthias Jucker and others at the Universities of Tübingen in Germany and Basel in Switzerland, discovered that aggregates of amyloid-β protein from the brain of people with Alzheimer’s disease could be transmitted to the brain of healthy mice. Another study by Patrik Brundin’s group in Sweden demonstrated that healthy tissue surgically implanted into the brain of people with Parkinson’s disease acquired the aggregates of α-synuclein protein characteristic of the disease. Eliezer Masliah of the University of California San Diego and others discovered that aggregates of a-synuclein can travel from cell to cell, forming the aggregates in human neurons that are characteristic of Parkinson’s disease and certain types of dementia. Anne Bertolotti from the University of Cambridge discovered that neuronal cells spontaneously and efficiently take up misfolded mutant SOD1 from their environment. The internalized mutant SOD1 triggers a change in shape of the normally soluble mutant SOD1 protein, which causes its aggregation, and is then transferred to neighbouring cells in a prion-like fashion.
Folks, you will not hear of this on the nightly news, and the doctors and nurses I’ve talked to have never even heard of a “prion”. But you can bet that they have heard of Merck, Astrazeneca, Sanofi Aventis, and Glaxo-Smithkline, because they get paid to sell their pharmaceutical drugs and vaccines!
The most logical and easiest to explain transmissible quality of prions is by far the vaccinations received by humans and animals, which again have been admitted by the vaccine manufacturers to contain DNA and proteins too small and numerous to filter out of the final vaccine product. Thus, we have over 100 million Americans and billions worldwide receiving a direct bodily injection of human and foreign animal proteins through vaccination. This is not a conspiracy theory, but fact – and this consideration of possible prion infection and transmission through vaccination is very likely just one of many dangers already known to the vaccine industry, but ignored due to the profit potential of vaccines. And since the direct blood-to-blood and blood-to-intramuscular transmission of prions in general is only possible under surgery conditions, the only logical transmission agents that would cause such wide-spread prion-based disease states and neuro-degenerative issues in both aging and prematurely young populations (early onset dementia) are the either the food supply and/or the vaccination process – which bypasses the stomach and digestive system’s natural defenses and disposal process.
Like the banking, automobile, and other corporate structures in America, the pharmaceutical industry that manufactures these vaccines may very well be considered “too big to fail” by government – and is certainly one of the most profitable. And these facts alone place a tremendous conflict of interest in seeing justice done by way of recognizing, prosecuting, and suing this industry as being the cause of this wide-spread dementia outbreak among humans – the end result being this industry’s and its shareholders inevitable financial ruin.
I alone cannot force an investigation to take place, and in its stead will be the same medical and pharmaceutical corporations creating drug “symptom-relievers” and “treatments” for the very prion-based diseases that they are now spreading, meaning profitable returns for these corporations and for government institutional investment funds – the main investor in these vaccine manufacture corporations.
I may not be recognized by future generations as the guy who yelled foul, but let this writing stand as a testament to the squashing of information that would literally cure the most profitable of diseases if only the people would participate in their collective quandary.
We stand upon a threshold of immense possibilities in the realm of curing most modern disease, including cancers and degenerative disease states. But without an outcry and outpouring from the people who have suffered by this debacle, nothing will ever be done to halt what I consider to be the greatest man-made plagues of our history. And the rates of suffering and profits will continue to rise, as this information will stay within the medical associations and corporations without publicity.
We are victims of our own ignorance and willful consent and compliance to the tyranny and oppression of deadly pseudo-science.
The following information is based solely on fact and sourced within.
This essay is an addendum to my documentary film, “Lethal Injection: The Story Of Vaccination“. It is of utmost importance that you read this entire article and spread it indefatigably.
What you are about to read may very well be the largest combined cover-up of the confederated government, ranching, meat-packing, medical, and pharmaceutical industry’s history – a collaborative effort to hide the true nature of what can only be called the human race’s modern plague of neurological and other degenerative diseases, from Alzheimer’s to AIDS.
This is not about the dead coming back to life. On the contrary, death is the only sweet release from this disease… a final cure that is always certain, and which never comes soon enough.
This is the real story of an apocalyptic peril that, as it turns out, very likely already lies dormant in us all.
This is not a zombie genre fiction, but is instead the real-life story of what are called “prions“.
The following essay affects anyone and everyone who may be reading this, without exception. This research is not an attempt to scare you or to promote science fiction. It is instead my personal attempt to save the world; to warn the entire planet of what “zombie” fans and fanatics could only before both dream about and dread, and in the end offer what I believe with all of my soul to potentially be the proverbial cure and end of prion-related diseases for ever.
But I digress… for most people – including many nurses and doctors – have never even heard of a prion, let alone considered them as the cause of such conditions that I now believe to be purposefully and falsely diagnosed as Alzheimer’s, Lou Gehrig’s Disease (Amyotrophic lateral sclerosis – ALS), Parkinson’s Disease, and many other debilitating conditions that most medical “professionals” will to this day admit – they do not know the cause of!
Dismiss this information at your own peril…
Or embrace it and fight for your life and your right to live it well!
–≈– What Is A Zombie?
–≈–
Sorry folks, but you’ll have to come down to Earth for this presentation! Please place all pre-conceived notions securely in the overhead bins and place all tray-tables in their upright and locked positions. It’s time to get real…
For the purposes of this essay, the term “zombie” is defined by the World English Dictionary as:
1. a person who is or appears to be lifeless, apathetic, or totally lacking in independent judgment; automation
And by Dictionary.com as:
2. Informal. a. a person whose behavior or responses are wooden, listless, or seemingly rote; automaton. b. an eccentric or peculiar person.
And Wikipedia gives this alternative description:
The term (zombie) is often figuratively applied to describe a hypnotized person bereft of consciousness and self-awareness, yet ambulant and able to respond to surrounding stimuli.
With the following descriptions in mind, and the Hollywood death worship, gore, and fanfare safely tucked away, we can now safely proceed with what I feel may be some of the most important information you may read in your lifetime.
And anyone who knows of me, certainly knows that I don’t say something like this lightly…
–≈– Cannibalism As Medicine –≈–
The virtually unknown and under-discussed scientific and medical topic of what is called “xenotransplantation“, as well as human protein ingestion – including injection (vaccination) of other animals and human cells into the human body – is now a practice as prevalent as the consumption of aspirin. From flavor enhancers labeled as “natural ingredients” or “natural flavors” to oral and inject-able pharmaceutical drugs ranging from insulin to human growth hormone to anti-blood clotting drugs to seasonal vaccines, the human race has unsuspectingly been transformed into a species that consumes itself “for medicinal purposes“.
Be it consumed orally, injected (vaccinated) through the skin to bypass the body’s natural defenses, or purposefully “xeno”-transplanted via surgical procedure, the deadly zombie-creating prion we are about to expose is officially undetectable, ineradicable, untreatable, irreversibly fatal, and unless good people take immediate action and demand public exposure and immediate research, unstoppable!!!
There is a distinct difference between animal and human consumption, both in application and in function. But the dangers in both cases are equally deadly – as in always deadly, without exception, meaning 100% fatal! The reasons for this fact will become inescapably apparent and self-evident as we read on…
–≈– What is Xenotransplantation?
–≈–
The FDA explains Xenotransplantation as:
Xenotransplantation is any procedure that involves the transplantation, implantation or infusion into a human recipient of either (a) live cells, tissues, or organs from a nonhuman animal source, or (b) human body fluids, cells, tissues or organs that have had ex vivo contact with live nonhuman animal cells, tissues or organs. The development of xenotransplantation is, in part, driven by the fact that the demand for human organs for clinical transplantation far exceeds the supply.
Currently ten patients die each day in the United States while on the waiting list to receive lifesaving vital organ transplants. Moreover, recent evidence has suggested that transplantation of cells and tissues may be therapeutic for certain diseases such as neurodegenerative disorders and diabetes, where, again human materials are not usually available.
Although the potential benefits are considerable, the use of xenotransplantation raises concerns regarding the potential infection of recipients with both recognized and unrecognized infectious agents and the possible subsequent transmission to their close contacts and into the general human population. Of public health concern is the potential for cross-species infection by retroviruses, which may be latent and lead to disease years after infection. Moreover, new infectious agents may not be readily identifiable with current techniques.
The FDA also has this information page regarding xenotransplantation:
Information and recommendations for Physicians Involved in the Co-Culture of Human Embryos with Non-Human Animal Cells
The U.S. Food and Drug Administration (FDA) wants you to know that the co-culture of human embryos with nonhuman animal cells raises health concerns for the recipients of such embryos, the offspring resulting from such embryos, and the general public. The use of nonhuman animal cells, tissues or organs in the treatment of human medical conditions is called xenotransplantation…
Co-culture of human embryos with nonhuman animal cells fits the second part of this definition (xenotransplantation, defined above). During co-culturing, human embryos and nonhuman animal cells are maintained together outside the body, in ex vivo contact. Thus, the woman into whom the co-cultured embryos are transferred is a recipient of a xenotransplantation product.
A serious concern regarding the clinical use of xenotransplantation is the potential for the transmission of infectious disease from nonhuman animals to humans. Scientists believe that the potential for transmission of an infectious disease from the animal source to a human is of concern either when live nonhuman animal cells, tissues or organs are implanted directly into a human, or when human cells are exposed to live nonhuman animal cells by ex vivo contact. Experience with organ allotransplantation has shown that diseases such as human immunodeficiency virus (HIV) infection, Creutzfeldt-Jakob disease, hepatitis B virus infection and hepatitis C virus infection can be transmitted from the human donor to the recipient. Similarly, xenotransplantation poses concerns for infection with recognized, or as yet unrecognized, infectious agents from nonhuman animals. These concerns may extend beyond the recipient to the general public because of the potential for subsequent transmission of an infectious agent to the recipient’s contacts and to the general population. Infections originating from animals that have been known to infect and be transmitted from human to human include, for example, HIV and swine influenza. Many viruses exhibit latency, so that the lack of symptoms at the time of the embryo transfer, or in the short term, does not alleviate all concern.
The U.S. Public Health Service has published guidelines on infectious disease issues in xenotransplantation. These guidelines, as well as FDA guidance documents, can be found at the website http://www.fda.gov/cber/xap/xap.htm, or obtained from FDA. They recommend, for example, that:
You should inform recipients of xenotransplantation products that they and their intimate contacts should defer from donation of blood and other tissues.
You should inform patients that they have been treated with a xenotransplantation product and of the risks involved.
You should archive patient samples, such as blood, to allow future monitoring for potential infections.
You should follow patients for their lifetimes and counsel them to be alert to any unusual symptoms.
You should archive samples of the xenotransplantation product. In this case, the nonhuman animal cells used for the co-culture process should be archived.
We would be happy to discuss any questions you might have about these recommendations. The nature and level of our concerns may vary depending on the species of nonhuman animal used in the co-culture technique and the source of the culture cells. We plan to have further public discussion of this topic with an appropriate federal advisory committee. At this time, FDA plans to enforce investigation new drug application (IND) requirements for investigations involving further production of embryos co-cultured with live nonhuman animal cells. However, currently it is not our intent to take enforcement action based on the transfer of already existing embryos created by co-culture with live nonhuman animal cells.
Has anybody considered that the growing of human body parts on animals is a gateway for new and more dangerous mutation of prion development and transmission? After all, the animal circulatory system will be directly fused during growth, and transferred during xenotransplantation into or onto the human host.
–≈–
In my film, “Lethal Injection: The Story Of Vaccination”, I covered in great detail the disturbing fact that cloned DNA from human aborted fetuses and other animal proteins are used in the production of vaccines and in the growth of cell substrates for vaccine cell growth (free to view on YouTube, –> here). Some viewers mistook this information as an attempt to promote a “pro-life” political standpoint, indeed missing the very real point that we are literally being forced into eating, injecting, and applying as cosmetics ourselves (other humans) with our unborn aborted children in the name of “medical science” and “beauty”. Thus, to say that “Soylent Green is people” is truly an understatement in modern medicine, food, and cosmetics. Indeed, everything is a choice.
Before we proceed, we must understand exactly what it is that gets directly injected into the human body via the vaccination process. Here is an incomplete list of human and non-human animal proteins and ingredients that are used in the vaccine and other inject-able drug markets. Note that these are listed as “ingredients” of different vaccines:
-residual MRC5 proteins – human diploid cellsfrom aborted fetal tissue – including DNA and proteins
-human albumin, albumin from human blood
-sucrose human albumin
-chicken embryo
-chick embryonic fluid
-chicken protein
-monkey kidney cells
-phenol red rhesus monkey fetal lung cells
-rhesus monkey fetal diploid cells
-rhesus monkey rotavirus
-3 rhesus-human reassortant live viruses
-guinea pig embryo cells
-mouse serum proteins
-gelatin (collogen – animal proteins, especially flesh and connective tissues. Aborted human fetal material also used in cosmetics)
-lactose (animal milk derived – also added to pills as a cheap “filler”)
-vesicle fluid from calf skins
–calf serum
–bovine fetal serum
–bovine extract, US sourced
–bovine gelatin and serum “from source countries known to be free of bovine spongioform encephalopathy” (Note: this is an impossible claim to prove.)
-Mycobacterium bovis
-polysaccharide from Salmonella typhi Ty2 strain
-recombinant protein (OspA) from the outer surface of the spirochete Borrelia burgdorferi kanamycin – a tick-borne pathogen that causes Lyme disease
(Older) List of vaccines with aborted fetal tissue (cloned):
These human and other animal proteins are all but impossible to filter out of the final inject-able product (vaccines), and are being introduced at an alarming rate into the human and animal population of the world with the advent of the popularity and profit-potential of vaccination on a world (United Nations) scale. While the moral implications of this barbarous and unethical practice are more than obvious and should seemingly be enough to defeat the ego when choosing whether or not to vaccinate ones self or ones children, there is a much more sinister and unknown danger in this practice that needs a bit of light shown upon it…
Introducing, the prion…
–≈– The Indefatigable Prion
–≈–
pri·on
noun \ˈprē-ˌän\ (Medical Dictionary)
Any of various infectiousproteins that are abnormal forms of normal cellular proteins, that proliferate by inducing the normal protein to convert to the abnormal form, and that in mammals include pathogenic forms which arise sporadically, as a result of genetic mutation, or by transmission (as by ingestion of infected tissue) and which upon accumulation in the brain cause a prion disease.
prion
noun(Concise Encyclopedia)
Disease-causing agent, discovered by Stanley Prusiner, responsible for various fatal neurodegenerative diseases called transmissible spongiform encephalopathies. An abnormal form of a normally harmless protein found in mammals and birds, the disease-causing prion can enter the brain through infection, or it can arise from a mutation in the gene that encodes the protein. Once present in the brain it causes normal proteins to refold into the abnormal shape. As prion proteins multiply, they accumulate within nerve cells, destroying them and eventually causing brain tissue to become riddled with holes. Diseases caused by prions include Creutzfeldt-Jakob disease, mad cow disease, and scrapie. Prions are unlike all other known disease-causing organisms in that they appear to lack nucleic acid (DNA or RNA).
–≈– Deadly Feasts
–≈–
I am seldom one to promote a book or movie, and yet I feel compelled to share this one with you – a 15 year old warning that has gone unheeded by the corporate and government profit machine, ignored by the media and medical community and as a result the conditioned and ignorant people, and brushed aside out of public view in an effort led by the WHO and the U.S. FDA and CDC.
“Deadly Feasts: Tracking The Secrets Of A Terrifying New Plague” was written and researched by Pulitzer prize winning author and researcher Richard Rhodes, published in 1997. I recomend that this book be on your “to read” list, if only to understand what is potentially the worst continuing outbreak of avoidable, man-induced disease in the history of the world.
If you’ve ever been vaccinated or eaten any type of meat or dairy products, you should really pay attention here…
The Introduction to the book, entitled “To The Reader”, states:
“The threat of Ebola virus has haunted our nightmares since Richard Preston published his “terrifying true story” The Hot Zone in 1994. Ebola hides in the African rain forest, but a deadlier disease than Ebola has begun killing young people in Britain and France. Ebola is a terrorist: it sickens people quickly and spares at least one out of ten. The new disease is a stealth agent: it incubates silently for years and kills every last victim it infects. Ebola is a sickness of fever and bleeding, no worse than cholera, a quick if not a merciful death. The new disease is an atrocity of destruction – a headache, a stumble, and then hallucination, palsy, seizure and coma drawn out horribly for months. Victims’ brains go spongy; their minds dim; they lose the ability to walk, to talk, to see, to swallow; they die slowly, drowning in pneumonia, or they starve to death.
Ebola can survive outside of the body for a few days at best. Sunlight kills it. Ultraviolet light kills it. The new disease agent refuses to die. Assault with pressurized, superheated steam in the autoclaves that hospitals use to sterilize instruments for surgery barely slows it. It remains deadly after hours of intense bombardment with hard radiation, months of soaking in formaldehyde, years of burial, decades of freezing. It survives even the fiery furnace of a seven-hundred-degree oven.
How Ebola spreads is still uncertain, but scientists know it’s a virus. In time, a vaccine will protect us from its threat (author’s note: I disagree with this vaccine statement, as is self evident in my film and research). The new disease turns up no virus in victims’ brains. It creeps past the barriers of species and immunity. Evidence accumulates that it’s a bad seed, a mistake of protein, a misshapen crystal that forces the brain to poison itself. If so, it’s a new kind of disease agent that can never be eradicated.
How the new disease spreads is known: it spreads in the cannibalism of animals by animals, it spreads in the industrial cannibalism of animal remains fed to animals, it spreads by the eating of beef…”
Deadly Feasts then discusses the cannibalistic rituals of the Fore tribal people who lived in New Guinea. More specifically, the “revenge” of the female members of the tribes who consumed (ate) the parts of their husbands and menfolk together with vigor and ritualistic joy – the result of the less than loving matrimonial customs of the Fore people. Each internal organ was extracted with care and precision, and then served with various plant sides, sweet potatoes, and other forest condiments.
A tradition that was started by the women of the tribes in the 1930’s, this cannibalism resulted in mass outbreaks of disease locally called “Kuru”. Kuru was thought by the women of the Fore tribes to be nothing short of witchcraft by the menfolk, whom were thought of as “sorcerers” in many Fore tribes. The native word “Kuru” literally meant shivering- in cold or from fear. And once the sorcery of Kuru took hold, the “bewitchment” would, without exception, lead to death.
Kuru’s symptoms are described as if taken straight of Night Of The Living Dead:
The symptoms of Kuru are broken down into three specific stages. The first, ambulant stage, exhibits unsteady stance and gait, decreased muscle control, tremors, deterioration of speech and dysarthria (slurred speech). In the second stage, sedentary stage, the patient is incapable of walking without support, suffers ataxia (loss of muscle coordination) and severe tremors. Furthermore, the victim is emotionally unstable, depressed, yet having uncontrolled sporadic laughter. Interestingly, the tendon reflexes are still normal at this point. In the final, terminal stage, the patient is incapable of sitting without support, suffers severe ataxia (no muscle coordination), is unable to speak, is incontinent (unable to restrain natural discharges/evacuations of urine or feces), has dysphagia (difficulty swallowing), is unresponsive to their surroundings, and acquires ulcerations (sores with pus and necrosis). An infected person usually dies within 3 months to 2 years after the first symptoms, often because of pneumonia or pressure sores infection.
Please note that the symptom called “necrosis” is defined as:
Necrosis:The death of living cells or tissues. Necrosis can be due, for example, to ischemia (lack of blood flow). From the Greek “nekros” meaning dead body.
Now, despite the fact that the hairs on your back of your neck may be standing up in fibrous nervousness about now, we haven’t yet begun to uncover the zombification of the world yet.
“Deadly Feasts” begins its story in Papa New Guinea with the true story of cannibalism and its cost:
“Men lived separately from the women and children, following their wives into their gardens to copulate, sharing the big men’s lodge with the older boys. Men believed contact with women weakened them. They resented the fecundity of women. Men seldom ate the dead and then only the red meat, surreptitiously…”
“The women at their mortuary feast butchered and cooked down in the garden, but they ate in private, carrying the steaming bamboo tubes back to their separate woman’s houses, sharing the feast with their children…”
“They ate every part of the body, even the bones, which they charred at the open fires to soften them before crumbling them into the (bamboo shoot) tubes. The dead woman’s brother’s wife received the vulva as her special portion. If the dead had been a man, his penis, a delicacy, would have gone to his wife…”
“Eating the dead was not a primordial Fore custom. it had started within the lifetime of the oldest grandmothers among them, at the turn of the century (1900) or not long before…”
“Women bewitched with Kuru staggered to walk, walked with a stick and then could no longer walk at all. Before losing the ability to swallow they got fat and the flesh of those who died early of pneumonia was rich meat…”
“Nevertheless, the damage Kuru caused to the brain was similar to the damage caused by the rare condition known as Creutzfeldt-Jakob disease(CJD).
Towards the end of the book, Mr. Rhodes discusses the phenomenon and likely scientific folly of xenotransplantation in an interview with Dr. David White, the cofounder and medical director of a company called Imutran:
“Pioneer xenotransplantation has already begun: in 1984 in the U.S., a baboon heart kept Baby Fae alive for twenty days: a baboon liver was transplanted in 1994; San Francisco AIDS patient Jeff Getty received a baboon-marrow graft in 1995 to shore up his immune system. Advanced biotechnology that may make xenotransplantation routine is under development in the United States and in Britain. Lines of transgenic pigs are being bred for use initially for hearty transplants. Pig blood types are more like human types than those of other animals, but a strong immune response known as hyperacute rejection normally destroys pig tissue grafted into primates in a matter of hours.
I investigated Imutran, a company based in Cambridge, England, that leads the world in xenotransplantation technology, and learned that it has cloned human genes that defeat hyperacute rejection and inserted them into pig embryos. Imultran has bred hundreds of pigs carrying these human genes. Rejection of transgenic pig hearts still has to be controlled with drugs, just as rejection of transplanted human hearts has to be controlled with drugs. In 1995, Imutran demonstrated that even without such immunosuppressive drugs, monkeys implanted with its transgenic pig hearts survived for five days – well past the time when hyperacute rejection would have destroyed an ordinary pig-heart implant. Implanted monkeys treated with immunosuppressive drugs survived up to sixty days. That achievement led Dr. David White, Imutran’s cofounder and medical director, to predict routine pig-heart transplants in humans before the turn of the century. “The big debate now,” White told the media, “is, do we currently have the skills to keep the hearts functioning in people for a long time; and the only way to answer that question is to put them into people and find out.”
I interviewed White at Imutran’s headquarters in Cambridge in April 1996. He was enthusiastic about his work. “Right from the beginning,” he explained, “our approach was to ask how can we genetically engineer the pig, not how can we treat the patient. From there, we realized that a possible approach would be to put these human regulators into a pig. And the smartest thing I ever did was to take out a patent on the process. Because that’s what pays all the bills.” Although I didn’t know it at the time, White had just sold Imutran to Sandoz Pharma, Ltd., a major drug company.
I will put my career on the line,” he told me, “and say that hyperacute rejection as we know it is dead, gone, finished. You take an organ from one of our pigs and transplant it into a primate and it will go for days without any treatment at all, routinely. We’ve done kidneys, islets [i.e. pancreatic tissue which secretes insulin, to correct diabetes], hearts – I don’t even know the number now, sixty or seventy. Now all we have to do is immunosuppress the monkey in order to achieve long-term survival. We did our first baboon transplant a couple of weeks ago, and on the same day that we successfully transplanted a baboon with a pig heart, one of our patients died waiting for a human heart.”
I came to the point of my visit: “Are you concerned with BSE?”
***Note that BSE stands for bovine spongiform encephalopathy (i.e. Mad Cow Disease).
“Fortunately,” White countered, “pigs don’t get BSE.”
“I think there’s evidence they do.”
“If you take contaminated brain from a mad cow and inject(vaccinate) the neural tissue directly into the brain of the pig it will get spongiform encephalopathy. But they’ve been feeding infected brain to pigs for five years no and none of the pigs has the disease.”
That was true.
“You have to appreciate that BSE is not an infection. It’s a very curious toxicity really.”
I told Dr. White I’d looked into it.
“Well,” he responded, “then perhaps you can tell me how the hell the bloody thing works. I don’t understand it.”
I tried to explain abnormal protein crystallization (caused by prions).
He listened. “Yes, that could work,” he said finally.
“Your pigs are isolated and presumably not fed meat-and-bone meal,” I prompted him.
“Oh no,” he confirmed. “Disease transmission is an area of considerable concern.” He left his desk and returned with a proprietary study as thick as a telephone book. “We put together a group of the world’s leading experts on pig disease and on the diseases that transplant patients get.” He opened the book. “I’ll just read you some of the headings. ‘Microorganisms Known To Be Pathogenic.’ ‘Microorganisms Pathogenic In Humans.’ ‘Microorganisms Known To Be Pathogenic In Pigs Bt Not Pathogenic In Humans.’ Microorganisms Not Known To Be Pathogenic But Similar To Microorganisms Pathogenic.” And so on. Porcine RNA viruses, porcine DNA viruses, exotic porcine RNA viruses, exotic porcine DNA viruses, a special section on the human measles viruses. Porcine bacteria – the gram negatives, the gram positives – and it goes on and on. A basic risk assessment of them all. A list of pathogens of most concern.” He closed the book. “So when you’ve done all that, you’re left with one problem, which is the retroviruses. We’re currently doing research on our primates to answer the question, will these pig retroviruses jump across the species barrier and recombine with human retroviruses? We haven’t finished, but we think the probability is extremely remote.”
***Author’s note: In my film Lethal Injection: The Story of Vaccination, we see various patents for using Porcine Zona Pellucida (pig ovaries) as inject-able vaccination birth control methods, for use in both animals and humans. The foreign ovary proteins cause an “immune response” in the vaccinated patient and the body’s natural defenses develop “antibodies” inadvertently for the body’s own (human) reproductive functions, while attempting to fight the foreign reproductive ovary or other proteins. This is but one example of xenotransplantation designed to control population growth in animals and humans…
“The pigs wont go to the hospital, White continued, The patient will come somewhere near the pigs. “That is,” he explained, “you will have a few dedicated specialist centers which do xenotransplantation. Those centers will have a sterile pig-production unit nearby. The patients will come there. It is ludicrous that you have to wait for fit, healthy people to die so that you can treat sick people. With a pig, you can come in and the physician will say, ‘I think you’re going to need a heart transplant. ‘You wouldn’t be at the end of the road. Maybe three months, maybe six months away. And we would modify your immune system so that you won’t reject pigs.
It occurred to me that we might be talking about more than hearts. “Are you planning to transplant other organs and tissues from the pig?”
“The heart, the lungs – all those former smokers, the market is huge – the kidney. Possibly the intestine. The substantia nigra is an area of great interest.”
I said: “What?”
“Bit of the brain,” White said. “For the treatment of Parkinson’s disease.”
I knew what substantia nigra was, I just couldn’t believe that a brilliant and innovative physician-businessman who had admitted he didn’t understand what causes spongiform encephalopathy (who does?) was planning to implant pig brain directly into the brains of humans.
In July of 1996, the Committee on Xenograft Transplantation of the U.S. Institute of Medicine, part of the National Academy of Sciences, endorsed xenografting on the grounds that the potential benefits outweigh the risks. “When the science base for specific types of xenotransplants is judged sufficient,” the committee concluded, “and the appropriate safeguards are in place, well-chosen human xenotransplantation trials using animal cells, tissues and organs would be justified and should proceed.” The committee cited “ample evidence,” however, that infectious agents could be transmitted from animals to humans, which indicated a danger “unequivocally greater than zero” that xenotransplantation could transfer new and deadly viruses across the species barrier. And it specifically mentioned transmissible spongiform encephalopathy (Mad Cow Disease).“
Most importantly, in analyzing the age-specific incidence of both bovine BSE and sporadic human CJD, Dr. Richard Kimberlin states:
“The shape of the age-specific incidence curve… implies that infection with a common strain [of CJD] occurs in childhood or adolescence, and that the median incubation period is 40 to 50 years.” German researcher Dr. Heino Diringer similarly defends and infectious cause: “It seems more than likely that… the sporadic cases of CJD always originate from direct or indirect transmission from animals to man.” In 1996, Deringer reported finding small virus-like particles in scrapie hamster brain…”
“Carleton Gajduserown freeze-dried a sample of scrapie brain, sealed the sample into a glass ampule and baked it in an oven for one hour at 360 degrees Celsius (nearly 700 degrees Fahrenheit). Reconstituted, the sample still transmitted scrapie to a hamster.”
At the end of his book, Richard Rhodes leaves us with these words (note: there are no spoilers here, just facts):
“I remember something he (Nobel-laureate virologist D. Carleton Gajdusek) asked me at our first meeting, late in 1995, before the British reported out the beginnings of what may be their new Black Death.
“You know the bone meal that people use on their roses?” Gajdusek asked me then. “It’s made from downer cattle. Ground extremely fine. The instructions on the bag warn you not to open it in a closed room. Gets up your nose.” The Nobel-laureate virologist who knows more than anyone else in the world about transmissible spongiform encephalopathy looked at me meaningfully. “Do you use bone meal in your roses?”
I told him I did.
He nodded. “I wouldn’t if I were you.”
The final blurb of Deadly Feasts is an article from the London Daily Telegraph, dated April 4, 1996:
“Gardeners have been reminded by the Royal Horticultural Society to wear gloves and a dust-excluding mask to avoid any risk of BSE when applying a spring dressing of blood and bonemeal to roses and shrubs.
Demand for beef is recovering steadily. At London’s Smithfield wholesale market, the trade in better quality cuts of British beef has recovered from zero a week ago to just over half the normal .
–≈– Creutzfeldt-Jakob Disease(CJD)
–≈–
Before we read the following report from the Mayo Clinic on CJD, and as we will see once again this clinic reiterating the fact that very few cases of CJD have been reported throughout the world (as has the FDA, CDC, WHO, etc…), we must begin to consider that on an international scale, “prion diseases” are being covered up – quite simply by means of diagnosing them as other diseases such as “Alzheimer’s Disease” – of which these same “organizations” claim not to know the origins or causes of.
In fact, on page 133 of “Deadly Feasts”, Dr. Carlton Gajdusek and Joe Gibbs are quoted as such:
“Gajdusek and Gibbs prepared a technical note for the Journal of Neurosurgery. They reviewed CJD transmissibility. They advised that it was reasonable to assume that the CJD agent was at least as resistant as the scrapie agent to heat, formaldehyde and ultra-violate light. “In particular,” the wrote, “one must assume the agent is not killed by boiling.” They pointed out that physicians often misdiagnosed CJD as Alzheimer’s disease,as the form of cerebral atrophy known as Pick’s disease, or as many other conditions including brain tumors and strokes. They recommended sterilizing instruments used on such patients in an autoclave – a machine used in hospitals that kills even hardy microorganisms with hot steam under pressure – for at least thirty minutes, twice the standard autoclaving time. They recommended treating all organs as infectious, even those fixed in formaldehyde. They had found only one chemical, chlorine bleach, that reliably killed the scrapie agent and they recommended using it to decontaminate floors and other surfaces where tissue might have fallen.
But before this technical note was published… from Deadly Feasts:
“Diseases doctors unintentionally cause are called iatrogenic, Greek for “physician-born”. The first known human-to-human transmission of spongiform encephalopathy outside the Fore was iatrogenic (by Dr. Arthor DeVoe, eye surgeon and chairman of the department of ophthalmology at the College of Physicians and Surgeons of Columbia University in New York)…
A donor became available, a middle aged man with a two-month history of memory loss and involuntary tremors who died of pneumonia. Down in the hospital morgue, an ophthalmologist harvested one of the man’s eyeballs, immersed it in sterile saline in a small jar and delivered it to surgery…
Holding the donor cornea like a contact lens, DeVoe lowered it over the hole in his patient’s eye. It fit perfectly. Meticulously, across the next hour, DeVoe joined the edges of the cornea and the woman’s eyeball together with stitches of fine nylon thread, burying the knots in the wound…
The eye healed. The woman could see again clearly through the dead man’s cornea and the operation seemed a success. But the optic nerve connects the eye directly to the brain, providing a channel for infection, and the brain of the man who died of pneumonia, who had not been autopsied until after his cornea was harvested, showed the characteristic damage of Creutzfeldt-Jakob Disease. A year and a half after her operation, the woman began feeling nauseated, had difficulty swallowing, came to drool and stumble and jerk, went spastic, went mute, gradually introverted into vegetable oblivion. Two years beyond her surgery, emaciated and bedsore, she mercifully died. On autopsy her brain looked like the brain of the man who had donated his cornea – like a sponge. If Arthor DeVoe had only known before the transplant operation. A sickness had oozed from the cornea he’d implanted and eaten holes in his patient’s brain.”
–≈–
Now, when we look at the description for “Alzheimer’s Disease”, which according to the preeminent Spongiform Encephalitis expert is actually a prion disease such as CJV, we see virtually the same symptoms listed.
Alzheimer’s Disease is the most common form of a whole class of diseases generically called “dementia”. There is no stated or listed cure for Alzheimer’s Disease, which worsens as it progresses, and it eventually leads to death without exception from one of the direct or indirect “symptoms”.
Like AIDS, Alzheimer’s is not a disease in and of itself within the medical books, but rather a description for the symptoms of a particular disease state that is not understood – and this is the case with thousands of disease states and their symptoms.
The NINCDS-ADRDA Alzheimer’s Criteria specify eight cognitive domains that may be impaired in AD: memory, language, perceptual skills, attention, constructive abilities, orientation, problem solving and functional abilities.)
Sound familiar?
Now let us consider the number of cases of Alzheimer’s worldwide, and the predictions for humanity’s future.
In 2006 the worldwide prevalence of Alzheimer’s disease was 26.6 million. By 2050, prevalence will quadruple by which time 1 in 85 persons worldwide will be living with the disease. We estimate about 43% of prevalent cases need a high level of care equivalent to that of a nursing home. If interventions could delay both disease onset and progression by a modest 1 year, there would be nearly 9.2 million fewer cases of disease in 2050 with nearly all the decline attributable to decreases in persons needing high level of care.
Interpretation: We face a looming global epidemic of Alzheimer’s disease as the world’s population ages. Modest advances in therapeutic and preventive strategies that lead to even small delays in Alzheimer’s onset and progression can significantly reduce the global burden of the disease.
(Source:“FORECASTING THE GLOBAL BURDEN OF ALZHEIMER’S DISEASE” – Johns Hopkins University, Dept. of Biostatistics Working Papers, Year 2007, Paper 130)
Suddenly, by taking into consideration only the Alheimer’s diagnosis’ worldwide as being an actual “prion disease”, the 1 in one million figure listed as supposedly confirmed worldwide cases of CJV becomes instead a true epidemic – the true black plague of humanity – of prion disease.
And Alzheimer’s is just one of the listed dementia diseases.
Dementia includes many disease descriptions, including the symptoms of this partial list:
Now what happens to all of these classifications/descriptions of disease states and their symptoms when we place them all into the same category of disease – prion disease? What indeed…? What if one thing is responsible for all of the above descriptions of the same disease?
The Mayo Clinic published this report on October 23, 2012:
–Begin report–
.
Creutzfeldt-Jakob Disease
By Mayo Clinic staff
Definition
Creutzfeldt-Jakob (KROITS-felt YAH-kobe) disease is a degenerative brain disorder that leads to dementia and, ultimately, death. Symptoms of Creutzfeldt-Jakob disease (CJD) sometimes resemble those of other dementia-like brain disorders, such as Alzheimer’s, but Creutzfeldt-Jakob disease usually progresses much more rapidly.
Creutzfeldt-Jakob disease captured public attention in the 1990s when some people in the United Kingdom developed a form of the disease — variant CJD (vCJD) — after eating meat from diseased cattle. However, “classic” Creutzfeldt-Jakob disease has not been linked to contaminated beef.
Although serious, CJD is rare, and vCJD is the least common form. Worldwide, there is an estimated one case of Creutzfeldt-Jakob disease diagnosed per million people each year, most commonly in older adults.
Symptoms
Creutzfeldt-Jakob disease is marked by rapid mental deterioration, usually within a few months. Initial signs and symptoms of CJD typically include:
Personality changes
Anxiety
Depression
Memory loss
Impaired thinking
Blurred vision
Insomnia
Difficulty speaking
Difficulty swallowing
Sudden, jerky movements
As the disease progresses, mental symptoms worsen. Most people eventually lapse into a coma. Heart failure, respiratory failure, pneumonia or other infections are generally the cause of death. The disease usually runs its course in about seven months, although a few people may live up to one or two years after diagnosis.
In people with the rarer vCJD, psychiatric symptoms may be more prominent in the beginning, with dementia — the loss of the ability to think, reason and remember — developing later in the course of the illness. In addition, this variant affects people at a younger age than classic CJD does, and appears to have a slightly longer duration — 12 to 14 months.
***Author’s note: Does this list of “symptoms” sound like a zombie to you? Sudden, Jerky movements with lack of reason or ability to think; an anxious monster unrecognizable as your mother, father, sibling, or friend due to “personality changes”, who when questioned can only utter guttural sounds due to “difficulty speaking and swallowing”?
Causes
Creutzfeldt-Jakob disease and its variants belong to a broad group of human and animal diseases known as transmissible spongiform encephalopathies (TSEs). The name derives from the spongy holes, visible under a microscope, that develop in affected brain tissue.
The cause of Creutzfeldt-Jakob disease and other TSEs appears to be abnormal versions of a kind of protein called a prion. Normally, these proteins are harmless, but when they’re misshapen they become infectious and can wreak havoc on normal biological processes.
How CJD is transmitted
The risk of CJD is low. The disease can’t be transmitted through coughing or sneezing, touching, or sexual contact. The three ways it develops are:
Sporadically. Most people with classic CJD develop the disease for no apparent reason. CJD that occurs without explanation is termed spontaneous CJD or sporadic CJD and accounts for the majority of cases.
By inheritance. In the United States, about 5 to 10 percent of people with CJD have a family history of the disease or test positive for a genetic mutation associated with CJD. This type is referred to as familial CJD.
By contamination. A small number of people have developed CJD after being exposed to infected human tissue during a medical procedure, such as a cornea or skin transplant. Also, because standard sterilization methods do not destroy abnormal prions, a few people have developed CJD after undergoing brain surgery with contaminated instruments. Cases of CJD related to medical procedures are referred to as iatrogenic CJD. Variant CJD is linked primarily to eating beef infected with bovine spongiform encephalopathy (BSE), the medical term for mad cow disease.
Risk factors
Most cases of Creutzfeldt-Jakob disease occur for unknown reasons, and no risk factors can be identified. However, a few factors seem to be associated with different kinds of CJD.
Age. Sporadic CJD tends to develop later in life, usually around the age of 60. Onset of familial CJD occurs only slightly earlier. On the other hand, vCJD has affected people at a much younger age, usually in their late 20s.
Genetics. People with familial CJD have a genetic mutation that causes the disease. The disease is inherited in an autosomal dominant fashion, which means you need to inherit only one copy of the mutated gene, from either parent, to develop the disease. If you have the mutation, the chance of passing it on to your children is 50 percent. Genetic analysis in people with iatrogenic and variant CJD suggest that inheriting identical copies of certain variants of the prion gene may predispose a person to developing CJD if exposed to contaminated tissue.
Exposure to contaminated tissue.People who’ve received human growth hormone derived from human pituitary glands or who’ve had dura mater grafts may be at risk of iatrogenic CJD. The risk of contracting vCJD from eating contaminated beef is difficult to determine. In general, if countries are effectively implementing public health measures, the risk is virtually nonexistent.
***Author’s note: For anyone that is familiar with FDA standards and the meat packing and dairy industries, as well as the use of beef bone meal and other beef products to feed cattle (cow cannibalism) along with the use of inject-able bovine growth hormone (cow to cow vaccination) as a standard of practice by factory farms, and of course we mustn’t ignore the abhorrent health conditions of these beasts while kept in piles of their own excrement and infectious dung, this last sentence is no reassurance with regards to “public health measures” and the risk being “virtually nonexistent” from the FDA, especially with food now imported from China and other developing countries.
Complications
As with other causes of dementia, Creutzfeldt-Jakob disease profoundly affects the brain as well as the body, although CJD and its variants usually progress much more rapidly. People with CJD usually withdraw from friends and family and eventually lose the ability to recognize or relate to them in any meaningful way. They also lose the ability to care for themselves, and many eventually slip into a coma. The disease ultimately is fatal.
Physical complications, all of which may become life-threatening, include:
Infection
Heart failure
Respiratory failure
…
Tests and diagnosis
Only a brain biopsy or an examination of brain tissue after death (autopsy) can confirm the presence of Creutzfeldt-Jakob disease. But doctors often can make an accurate diagnosis based on your medical and personal history, a neurological exam, and certain diagnostic tests.
The exam is likely to reveal such characteristic symptoms as muscle twitching and spasms, abnormal reflexes, and coordination problems. People with CJD also may have areas of blindness and changes in visual-spatial perception.
In addition, doctors commonly use these tests to help detect CJD:
Electroencephalogram (EEG). Using electrodes placed on your scalp, this test measures your brain’s electrical activity. People with CJD and vCJD show a characteristically abnormal (brain) pattern.
Magnetic resonance imaging (MRI). This technique uses radio waves and a magnetic field to create cross-sectional images of your head and body. It’s especially useful in diagnosing brain disorders because of its high-resolution images of the brain’s white matter and gray matter.
Spinal fluid tests. Cerebral spinal fluid surrounds and cushions your brain and spinal cord. In a test called a lumbar puncture — popularly known as a spinal tap — doctors use a needle to withdraw a small amount of this fluid for testing. The presence of a particular protein in spinal fluid is often an indication of CJD or vCJD.
Treatments and drugs
No effective treatment exists for Creutzfeldt-Jakob disease or any of its variants. A number of drugs have been tested — including steroids, antibiotics and antiviral agents — and have not shown benefits. For that reason, doctors focus on alleviating pain and other symptoms and on making people with these diseases as comfortable as possible.
Prevention
There is no known way to prevent sporadic CJD. If you have a family history of neurological disease, you may benefit from talking with a genetics counselor, who can help you sort through the risks associated with your particular situation.
Preventing iatrogenic CJD
Hospitals and other medical institutions follow explicit policies to prevent iatrogenic CJD. These measures have included:
Exclusive use of synthetic human growth hormone, rather than the kind derived from human pituitary glands
Destruction of surgical instruments used on the brain or nervous tissue of someone with known or suspected CJD
Single-use kits for spinal taps (lumbar punctures)
To help ensure the safety of the blood supply, people with a risk of exposure to CJD or vCJD aren’t eligible to donate blood. This includes people who:
Have a biological relative who has been diagnosed with CJD
Have received a dura mater brain graft
Have received human growth hormone
Spent a total of at least three months in the United Kingdom from 1980 to 1996
Spent five years or more in France from 1980 to the present
Received a blood transfusion in the U.K. between 1980 and the present
Have injected bovine insulin at any time since 1980
***Author’s note: The American Diabetes Association lists the total number of official diabetics in the United States, as of January 2011, at 25.8 million people, or 8.3% of the population, with approximately 7 million of those listed as “undiagnosed”, and with 1.9 million new cases diagnosed in people aged 20 or older in 2010. It also lists an estimated 79 million more cases of “prediabetes”, the precursor symptoms to diabetes. This represents a whole lot of inject-able insulin shots.
Preventing vCJD
The risk of contracting vCJD in the United States remains extremely low. So far, only three cases have been reported in the U.S. According to the Centers for Disease Control and Prevention, strong evidence suggests that these cases were acquired abroad — two in the United Kingdom and one in Saudi Arabia.
In the United Kingdom, where the majority of vCJD cases have occurred, fewer than 200 cases have been reported. After its first appearance in 1995, CJD incidence peaked between 1999 and 2000, and has been declining since.
Regulating potential sources of vCJD
Most countries have taken steps to prevent BSE-infected tissue from entering the food supply, including tight restrictions on importation of cattle from countries where BSE is common; restrictions on animal feed; strict procedures for dealing with sick animals; surveillance and testing methods for tracking cattle health; and restrictions on which parts of cattle can be processed for food.
The risk of vCJD from the following sources is estimated to be extremely low:
Vaccines.Some parts of cows, including blood, enzymes and amino acids, are used to grow the bacteria and viruses needed to make certain vaccines. Not all vaccines are grown in cattle parts, however, and the Food and Drug Administration (FDA) recommends that companies producing such vaccines use cattle parts only from low-risk countries. These recommendations apply to cosmetics as well. The FDA keeps a listing on its website of companies that use cattle from countries that aren’t classified as low-risk.
Insulin. Insulin sold in the United States isn’t derived from cattle, but you’re allowed to import beef insulin from other countries if you follow specific guidelines. Because there’s no way to guarantee the safety of imported insulin, talk to your doctor about the best way to obtain insulin from sources outside the United States.
–End Mayo Clinic report–
–=– “Woman with Mad Cow Disease donated her eyes”
–=–
The Associated Press reported in December of 1997 that:
LONDON – Scottish health authorities are investigating how tissue from the eyes of a woman who had suffered from the human form of `mad cow disease” was transplanted into three other people.
“We are aware there is a potential infection risk from tissue retrieved from a patient in Scotland,” a spokesman for the government Scottish Office said Saturday on customary condition of anonymity. “We do not know the full facts, but we are making urgent inquiries into how this could have occurred,” he said.
The 53-year-old woman suffered from lung cancer, but after she died a post-mortem examination showed she also had Creutzfeldt Jakob Disease. The brain-destroying disease is the human form of bovine spongiform encephalopathy, which afflicts cattle and is known as ‘mad cow disease’.”
No further details were given on the grounds of patient confidentiality. But the tabloid Sunday Mail said the post-mortem findings were not passed on to officials handling organ donor arrangements, and parts of her eyes, including the corneas, were transplanted into two men and a woman in her eighties.
Remember what the FDA stated from above?
“Currently ten patients die each day in the United States while on the waiting list to receive lifesaving vital organ transplants…”
Is it at all reasonable to assume that the FDA, Red Cross, AMA, ADA, or any other “association” out there can screen body parts for prions, including these CJD and other variants of “Transmissible spongiform encephalopathies (TSEs)”, also known as prion diseases, considering that they are undetectable without the victim being dead first?
The Red Cross blood donation guidelines website states:
Creutzfeldt-Jakob Disease (CJD)
If you ever received a corneal (eye) transplant, a dura mater (brain covering) transplant or human pituitary growth hormone, you are not eligible to donate. Those who have a close blood relative who had Creutzfeld-Jacob disease or who is in a family that has been told they have a genetic risk for Creutzfeld-Jacob disease are also not eligible to donate. Learn more about CJD.
Interestingly, the supplied links to learn more information about CJD and vCJD do not link to anything, and a search on this Red Cross website for CJD turns up no search results.
Prion related disease is not limited to brain functions, and is a virtually unknown field of research when it comes to the rest of the human body.
Science Daily reported in August of 2009:
Prion Protein Identified As Novel Early Pancreatic Cancer Biomarker
ScienceDaily (Aug. 18, 2009) — Mad cow disease is caused by the accumulation of an abnormal protein, the prion, in the brain of an affected patient. Outside of the brain, very little is known about prions. Case Western Reserve University School of Medicine, researchers have, for the first time, identified the prion as a biomarker for pancreatic cancer. Pancreatic cancer is one of the most deadly cancers in humans; the five year survival rate is less than 10 percent.
Chaoyang Li, Ph.D., Wei Xin, M.D., and professor of pathology, Man-Sun Sy, Ph.D., discovered the mechanism by which prions causes tumors to grow more aggressively. They published these findings in the September issue of the Journal of Clinical Investigation.
Unlike normal cells, in human pancreatic cancer cells the prion is incompletely processed and binds to a molecule inside the cell known as filamin A. Filamin A is an important regulator of the cell’s skeleton and its signaling machineries. The binding of the incompletely processed prion to filamin A disrupts the cell’s organization and signaling. As a result, the tumor cells grow more aggressively. On the other hand, when the prion level is reduced, the tumor cell loses its ability to grow in tissue culture and in animals. Most importantly, Dr. Li, et al. found that a subpopulation of patients had incompletely processed prion protein in their pancreatic cancer. This subgroup of patients had significantly shorter survival compared to patients whose tumors do not have prion.
According to Dr. Sy, “Currently there is no early diagnostic marker for pancreatic cancer. Detection of the incompletely processed prion may provide such a marker. Preventing the binding of prion to filamin A may open new avenues for therapeutic intervention of this deadly disease.”
Next, Drs. Li and Sy will look to determine if this type of prion protein expression is seen in other types of cancer.
There are other examples of truth seeping its way into the public’s eye…
Prions and cancer: A story unfolding
Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles. They are proteins in which the complex molecular three-dimensional folding process just went astray. For reasons not yet understood, the misfolding nature of prions is associated to their ability to sequester their normal counterparts and induce them to also adopt a misfolding conformation. The ever-growing crowd of misfolded proteins form the aggregates seen in diseases such as Parkinson’s and Alzheimer’s. Once misfolded, a protein can no longer exert its normal functions in the cell.
Now, a group led by Dr Jerson Lima Silva at the Federal University of Rio de Janeiro, Brazil, presents some new evidence that p53, a protein with the daunting task of suppressing tumor formation in the body, may show a typical prion-like behavior when mutated.
It has been known for some time that the buildup of p53 in the cell impairs the protein in preventing tumor growth. This has been observed in neuroblastoma, retinoblastoma, breast, and colon cancers. In a paper entitled “Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: Implications for cancer” and published in the Journal of Biological Chemistry, the group shows that in breast cancer cell lines carrying the most common p53 mutation, the formation of amyloid-like aggregates of p53 proteins may explain the protein’s lack of function.
Whether this prionoid behavior in fact represents a relevant cancer-related mechanism remains to be shown. Development of novel and ingenious strategies to prevent p53 misfolding and aggregation may be just one way to find out.
“We are planning pre-clinical tests with synthesized nucleic acids in an attempt to prevent the changing in conformation of normal p53, and avoid aggregates of misfolded protein,” says Dr. Silva.
If successful, the strategy may help unveil unforeseen molecular mechanisms leading to tumor development. Considering that more than half of the cancers lose p53 function, this prionoid behavior may serve as a potential novel target for cancer therapy, dramatically transforming our way of thinking of cancer and treating cancer patients.
(Source: “Prions and cancer: A story unfolding”)
The good news about prions
By Nancy Shute
Posted 1/11/04
Last month’s discovery of mad cow disease in the U.S. food supply has elevated prions from an obscure biological curiosity to topic A on the talk shows. But just as these villainous, twisted proteins are becoming notorious, researchers are saying: Hold up; they might not be so bad after all. Indeed, prions and their cousin proteins may prove to be benign–even helpful–in normal mental functions like memory.
The same biological tenacity that can devastate the brain, it turns out, may also guard the memory of that first day in kindergarten or that first kiss. And although mad cow and its human version are rare, an understanding of why prions go bad could lead to treatments for diseases as common as cancer and diabetes.
No one really knows why prions exist. And no one knows how memories persist through time. So Nobel laureate Eric Kandel and Susan Lindquist, a prion expert at the Whitehead Institute in Cambridge, Mass., combined a protein involved in learning and memory with yeast prions. The experiment, published last month in Cell, revealed that the memory protein worked while in a stable, prionlike form, suggesting that it could be the mechanism needed for storing memories in brain synapses for decades on end. “We’ve shown for the first time that a prion in its self-perpetuating mode could have a normal physiological function,” Kandel says. His lab is now testing this startling hypothesis in flies and mice. If it proves true, it could illuminate a key mystery of the brain.
Origami. Prions may also hold clues to combating common diseases, because they are simply normal proteins that are misfolded. Misfolded proteins, it turns out, cause a host of major ailments, from cancer and diabetes to Alzheimer’s and Parkinson’s. Proteins are the workhorses of living things; the human body makes at least 50,000 different ones for tasks from building bones and muscle to digesting food and thinking.
As proteins form within cells, their long chains of amino acids fold up like fiendishly intricate origami. Since the 1930s, scientists have known that a protein’s folded shape is key to its function, making it possible for hemoglobin to carry oxygen or for collagen to bind together skin. But figuring out how and why proteins fold the way they do has become one of the great, enduring challenges in biochemistry.
It’s easy for proteins to get corrupted while folding in the crowded confines of a cell, and misfolded proteins can cause all sorts of trouble. One example is the P53 protein, the body’s frontline warrior against cancer. Misfolded P53s lose their tumor-suppressing power, an error that causes about half of all cancers. Cystic fibrosis, too, is caused by misfolded proteins, as is diabetes. Prions are more malevolent, forcing nearby proteins to misfold, too, unleashing a destructive chain reaction. Although Alzheimer’s and Parkinson’s are not known to be caused by prions, the disease process, in which brain proteins glom together into plaques, looks remarkably like that of mad cow and other prion diseases. “We’re starting to think there may be similarities between many diseases of misfolding,” says Jonathan Weissman, a prion researcher at the University of California-San Francisco, “including infectious prion diseases like mad cow and noninfectious diseases like Alzheimer’s.”
Cellular prion protein promotes invasion and metastasis of gastric cancer
Abstract
Cellular prion protein (PrPc) is a glycosylphosphatidylinositol (GPI) -anchored membrane protein that is highly conserved in mammalian species. PrPc has the characteristics of adhesive molecules and is thought to play a role in cell adhesion and membrane signaling. Here we investigated the possible role of PrPc in the process of invasiveness and metastasis in gastric cancers. PrPc was found to be highly expressed in metastatic gastric cancers compared to nonmetastatic ones by immunohistochemical staining. PrPc significantly promoted the adhesive, invasive, and in vivo metastatic abilities of gastric cancer cell lines SGC7901 and MKN45. PrPc also increased promoter activity and the expression of MMP11 by activating phosphorylated ErK1/2 in gastric cancer cells. MEK inhibitor PD98059 and MMP11 antibody (Ab) significantly inhibited in vitro invasive and in vivo metastatic abilities induced by PrPc. N-terminal fragment (amino acid 24–90) was suggested to be an indispensable region for signal transduction and invasion-promoting function of PrPc. Taken together, the present work revealed a novel function of PrPc that the existence of N-terminal region of PrPc could promote the invasive and metastatic abilities of gastric cancer cells at least partially through activation of MEK/ERK pathway and consequent transactivation of MMP11.—Pan, Y., Zhao, L., Liang, J., Liu, J., Shi, Y., Liu, N., Zhang, G., Jin, H., Gao, J., Xie, H., Wang, J., Liu, Z., Fan, D. Cellular prion protein promotes invasion and metastasis of gastric cancer.
State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, the Fourth Military Medical University, Xi’an, Shaanxi Province, P. R. China
Correspondence: State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, the Fourth Military Medical University, 17 Changle Western Rd., Xi’an, Shaanxi Province, 710032, P. R. China. E-mail: fandaim@fmmu.edu.cn
–≈– A Conclusion, Rife With Controversy
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So what about the zombie apocalypse, you ask?
Well my friends, you are currently living through it!
Chances are you were born with the gift of transferred dormant prions from your parents – the gift that keeps on giving.
And the chance that you were, at some time in your life, vaccinated with prion cells is more than likely.
And even if you’ve been a vegetarian your whole life, you have certainly ingested or inhaled animal proteins, such as by taking vitamins in “gelatin” capsules.
You are the walking dead…. you just don’t know it yet; cursed with dormant, brain-eating, mutant prions that will eventually be stimulated and awakened by some “environmental” cause only to subsume and convert other innocent prions into folded crystal zombies – better to devour your brain, my pretty. In short, your brain and body is a prion zombie apocalypse just waiting to happen.
I have no doubt that one of the many prion diseases will take your life; but not before your friends and family watch as you zombify before them, your children visiting you in the west wing of George Bush Memorial Hospital wondering where the old mom or dad went to, and who is this zombie laying there with “Alzheimer’s Disease”? After all, nurses have descriptively nicknamed Alzheimer’s and other dementia patients as “hitters”, “kickers”, “wanderers”, and of course, we can’t forget “biters“.
But let’s steer clear of these horrible zombie-like thoughts, and let’s try not to think about the government’s weapons labs around the country experimenting on different prions, causing them to predictably and unpredictably mutate, and of course, just for fun, seeing if they can be transferred through a bite without dormancy, and attaching them to such things as nano-technologies.
No reason to revolt against the establishment… Nothing to see here…
–=–
It is my belief that the suppressed work and technology of Royal Raymond Rife and of those before and after him even today are the key to ending this prion induced zombification of the people of Earth, and to ending the profitable suffering of generations to come.
While radiation, heat, time, and chemicals will not destroy the infections nature of mutated prions, I believe that this most suppressed of technologies is the one thing not available or known about to those doing the testing.
Here’s the thing…
“The newspaper article provided here was included in a newspaper called The Planet and published February 1986 in Washington, D.C. It was delivered to every member of the U.S. House of Representatives and every member of the United States Senate. Not one representative, senator or staff assistant was motiviated sufficiently to investigate further.
The newspaper was also provided free to the George Washington University Medical School students and professors. Again, not one was motivated to investigate further. All while 7,000 to 10,000 Americans died weekly from cancer!
Good examples of public irresponsibility from people in positions of public trust or professions with public trust implied! Shame!
–Barry Lynes, September 25, 1999
The Cancer Cure That Worked: The Rife Report was published in April 1987, 14 months after the U.S. Congress turned its back on Rife and ignored an incredible opportunity to “jump start” the Rife revival.”
Barry Lynes wrote in 1999 what I am writing here, now in the end of 2012… a pleading for the people of the United States and the world to stand up and demand action, to demand research, and to demand an end to the zombie black death machine that is prion disease in its many hundreds of forms, all separately diagnosed and treated with purposeful ignorance and massive profits.
Barry Lynes article as posted in “The Planet” breifly explained the life and work of Royal Rife:
A mobilization is required, for not only cancer, but AIDS and many other diseases threatening us are potentially capable of being eradicated if we, the people of the United States, get off our collective asses.
In the 1920s a scientist-inventor named Royal Raymond Rife invented a new kind of microscope. In an article in New Age Journal March produced little from New readers), the story of Rife’s cancer cure was detailed. Since then, Rife has been nominated for the “Alternative Nobel Prize” which is annually awarded in Europe as a protest to the more established, less risk taking Swedish honor. Yet, little notice of Rife and his miraculous discovery has infiltrated the establishment consciousness.
Rife’s microscope was a stunning advance. Unlike the electron microscope, Rife’s microscope made it possible to study “living” bacteria, viruses, and so forth. An electron microscope kills its specimens. Rife’s remarkable breakthrough used a new approach to bend light. As a result, Rife was able to prove that bacteria could change their form. In effect, they could become cancer causing viruses.
Rife then implanted his cancer-causing bacteria into rats. Tumors subsequently developed. From here, Rife made the startling discovery that the bacteria could change into a completely different form if the “medium on which they were living” was slightly altered. In other words, Rife’s cancer causing substance was, in some forms and in association with some environments within the body, deadly. But in other forms and in other environments, benign. His cancer causing substance could be changed back and forth from one to the other. The implications of this discovery are obvious. Cancer cells might be transformed to healthy cells again!
Rife then began beaming different frequencies of light on these microorganisms. Up until the early 1950s, Rife perfected this method. As Christopher Bird reported in the NewAge article, “tuberculosis, typhoid, leprosy. . . appeared to disintegrate or ‘bIow up’ in the field of his microscope.” This “death ray” was applied to cancers in rats. It worked!
The next step was humans. The result? Here is Rife’s report: “The first clinical work on cancer was completed under the supervision of Milbank Johnson, M.D., which was setup under a special medical research committee of the University of Southern California. Sixteen cases were treated at the clinic for many types of malignancy. After three months, fourteen of these so-called hopeless cases were signed off as clinically cured by a staff of medical doctors and Alvin G. Foord, M. D., pathologist for the group.
Throughout the 1930’s, Rife and associates continued their work. In 1940, Arthur W. Yale, M.D. reported that Rife’s discoveries were an entirely new theory of the origin and cause of cancer, and the treatment and results have been so unique and unbelievable” that we’ may be able to “eliminate the second largest cause of deaths in the United States.“
But it was not to be!
There were powerful doctors whose careers were based on the theory that bacteria could not change its form. Rife’s discovery threatened their status and their own research. (It was like the invention of the automobile for a horse-drawn carriage driver.)
One of these “authorities” was Dr. Thomas Rivers of the Rockefeller Institute. Another was Harvard microbiologist Dr. Hans Zinsser. The cancer cure was killed by the powerful.
One of Rife’s supporters, Dr. Edward C. Rosenow, a pioneer bacteriologist, sadly commented at the end of his life, “They simply won’t listen.“
Others have followed Rife and have confirmed different aspects of his theory, but since they are few in number and are promoting a cause contrary to the medical establishment’s approved philosophy, they are not supported. Even publishing their findings is difficult if not impossible because of the dominant medical orthodoxy which has reigned since the 1930s!
Christopher Bird’s 1976′ New Age Journal article contained a summation of the political coverup as perceived by the Lee Foundation of Nutritional Research in Milwaukee. According to Bird, the Lee Foundation “maintains that Rife, his microscope and his life work were tabooed by leaders in the U.S. medical profession and that any medical doctor who made use of his practical discoveries was stripped of his privileges as a member of the local medical society.“
The Food and Drug Administration (FDA) still bans treatments similar to those of Rife.“
–=–
Now, we must realize that Royal Raymond Rife’s frequency research and suppressed technologies took place before the discovery of prions as mutated proteins in the 1960’s. It is my belief that Rife’s research would have eventually located and destroyed the mutated form of prions which cause disease today.
Like Royal Raymond Rife, someone like myself – who is shunned by the mainstream medical (for-profit) profession – can only rely on you the reader of this information to spread, disseminate, and demand that this information be made public and that this prion disease plague that is now killing our elderly, our young adults, and our youngest of children be stopped and prevented.
Currently, the pharmaceutical drug industry is not interested in developing curative or preventative medicines, as that would be anti-corporation in that it would lower profits and take away from shareholder dividends and returns on investments.
Case in point:
The New York Times reported this article in 2008. Note that this was posted not in the health and wellness section… but in the “business” section:
Pfizer to focus on more profitable diseases
Published: Tuesday, September 30, 2008
NEW YORK — Pfizer, the world’s largest drug maker, is ending early-stage development of treatments for a range of illnesses from obesity to heart disease to focus on more profitable diseases.
Pfizer expects to spend $7.2 billion to $7.5 billion on research and development this year, a huge budget for the industry. “Even though it is very large, it is finite,” a Pfizer spokeswoman, Liz Power, said Tuesday.
The changes will not affect drugs in the last of three stages of testing needed for U.S. approval, including the anti-clotting drug apixaban being developed with Bristol-Myers Squibb, Pfizer said in a Sept. 25 memo to employees and confirmed Tuesday. Development will end on at least 11 drugs, including 6 studied for obesity and heart disease and three for digestive disorders.
In a recent interview, Jeffrey Kindler, chief executive of Pfizer, said the company would focus its research budget on medicines for cancer, pain, Alzheimer’s disease and diabetes. Pfizer’s cholesterol pill, Lipitor, the world’s best-selling drug, with $12.7 billion in 2007 revenue, is set to lose patent protection in 2011. Products for cancer and pain are typically more profitable because the makers can charge a higher price, and there is less competition.
Pfizer has identified six high-priority areas for research: cancer, pain, inflammation, diabetes, Alzheimer’s disease and schizophrenia.
“These large markets, with rapidly advancing science, are the areas where Pfizer can take a leading position,” the memo said.
Kindler said Pfizer would look to make more acquisitions to fill its pipeline of experimental medicines. Analysts say the company may consider buying ImClone Systems, which makes the cancer drug Erbitux. ImClone has said it received a $70 a share bid by a large drug maker it would not identify. Ray Kerins, a spokesman for Pfizer, said it would not comment on market rumors or speculation.
The memo said Pfizer would also stop early-stage research in anemia, bone health, liver disease, muscle, obesity and some osteoarthritis compounds. Pfizer had 102 drugs in development, including 47 in the first stage of testing and 37 in the second phase, according to the company’s most recent pipeline list, which was updated on Feb. 28. About 20 percent of Pfizer’s research financing now goes toward cancer.
The restructuring will not result in facility closings, and many employees will be shifted to other areas of research, the company said.
Pfizer began reorganizing its research operations in 2007 after halting development on its most promising experimental drug, the cholesterol pill torcetrapib, which was projected to have more than $13 billion in annual sales.
$100 bucks says “Viagra” isn’t on the list of research or patented products to be cut…
Now, besides the blatantly inhuman undertones of this report, stating or at the very least alluding to the fact that profits are of paramount precedent over cures and “promising” drugs, did you notice that the most profitable areas of research and drug development are for the very ailments caused by prion related diseases? Cancer, Alzheimer’s, diabetes, and dementia-related diseases such as schizophrenia… Phizer is not creating preventatives or cures here, but is instead creating symptom relief drugs in order to profit from the ongoing disease. Healing the symptoms is not healing the disease, but is instead profiting from the disease by temporarily treating and relieving only the symptoms caused by the profitable disease.
And this is how our medical and pharmaceutical industry operates as business as usual – symptom relief in lieu of disease prevention and cure.
This unavoidable fact should be quite clear to anyone reading this, straight from the Pfizer horses mouth.
And with this fact in mind, isn’t it time to break the stranglehold and monopoly that this government protected trust of drug and medical associations and corporations has upon the treatment of disease?
The problem is, as Mr. Jeffrey Kindler, chief executive of Pfizer confirmed above, is that in order for this to happen, the American people must “get off of their collective asses” and overthrow this profit-driven medical monopoly that all but promotes prion disease related illnesses for the simple reason and greed of shareholder returns.
It would mean that the people (currently and collectively on their posteriors) would actually have to support someone like me or the many proponents of Rife, Tesla, and so many others who have perfected this technology, which is illegal to utilize publicly as “practicing medicine without a license”, according to the FDA.
But someone like me or someone like Rife will not be embraced by the medical, scientific, or educational “establishment”, and so my research and their discoveries will never reach the people… unless the people say no to the establishment or demand with threat of violence that prion diseases are immediately treated as such.
Will this happen? Will a revolution in the governance of medicine and science take place within my lifetime? As I contemplate my current financial situation, the lack of support, the seemingly hopeless uphill battle to simply inform people without help from a for-profit media… I suppose I can only think about that now famous ad campaign which states that, “A mind is a terrible thing to waste.”
Please, don’t let my efforts here and those of the few suppressed people out there who can actually heal and prevent these profitable diseases (and who would gladly do so without a profit margin) go to waste. Share this information with all you know; with your parents who are reaching the 50 year incubation mark of prion dormancy, with your children who are falling pray to early-onset Alzheimer’s and other prion caused diseases and 1 in 3 with prion related cancers, and with doctors, nurses, and scientists who believe they know what disease is, but really only know what the pharmaceutical and corporate sponsored and written textbooks tell them they know.
The suffering and death on this planet can be halted, prevented, and so much pain can be avoided. But only if the people finally revolt and stop supporting the “establishment”.
To those who blindly invest in the stock of these corporations, I can only ask why? Profit at your own expense? Support of your own enslavement to the medical and pharmaceutical industries?
Are the people so clueless that they would invest in something irregardless of that investments consequences simply because there are dollar signs and investment returns on the other side? This is certainly what government and its pension and other investment fund schemes do. Profit and expansion of profit-making disease is what keeps these companies profitable.
Why do we consent to the federal government “granting” 100’s of billions of dollars to these corporations for “research and development”, placing the bill for that grant on the taxpayers, when we know that those pharmaceutical companies are not out to cure disease, and in fact cause more profitable diseases and symptoms that they help, insuring more profit and more diseases?
And to those who have made fortunes off of this medical and pharma industrial toxic waste production, how can you live knowing that your fortunes were made off causing disease in other people and suppressing the cure for that disease?
How can you live with your fortune when it relies on the suffering of others, and likely yourself in the future?
–≈–
If this writing and research has opened up your eyes or has given you a fragment of hope in an otherwise dark and hopeless world, and you would like to see this information turned into a documentary film, please consider making a donation to myself at the following link:
Without the support of the people, I am dead in the water – just like so many who would change and heal the world if only they were given the chance without such organized supression.
If you would like to start an organization or non-governmental research trial for the use of frequency in the treatment of and curing of infectious prions, please contact me and let’s do it! It is doubtful that I will ever receive a research grant in a for-profit world. Perhaps you know somebody who can? Whatever the case, this should be priority number 1!!!